311494
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
17
8
8
8
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
5
-1
8
1
1
2
2
3
3
4
5
6
7
7
7
8
9
9
10
10
11
11
11
12
12
13
13
14
14
15
15
16
16
16
17
17
19
19
20
20
22
22
23
24
18
11
15
12
21
21
8
8
9
21
31
22
10
13
14
16
12
25
26
27
28
17
29
18
30
19
20
32
33
34
18
35
23
36
24
37
23
24
38
39
1
1
1
1
1
2
1
2
1
1
1
1
2
1
1
1
1
1
1
1
1
2
1
2
1
2
1
1
1
1
1
1
1
1
2
1
2
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
8.055
-2.0469
0.564
2.574
-7.2417
-6.4859
2.4231
-6.3897
3.7503
4.0679
-1.594
-0.0994
4.7641
5.399
-3.115
3.0023
6.0953
6.4126
-4.0675
-3.2354
1.9285
-5.2828
-5.155
-4.3227
-1.7615
-2.1159
0.2635
0.1196
4.6026
5.6497
1.7149
2.3085
2.4494
3.4213
6.8759
-4.0211
-2.4896
-5.887
-4.3893
-1.5332
1.7359
1.4948
2.5567
-1.2466
-2.6831
0.2261
-1.6007
-0.2051
-1.5605
2.546
2.7632
0.7394
-1.9715
0.9154
-2.5939
0.3285
-1.027
1.2936
-0.2876
1.5249
-0.7503
0.4581
-1.1231
2.054
3.5086
3.4033
3.2299
1.8051
-3.0276
-0.4926
-2.5769
-2.4257
-3.6049
1.0746
2.2386
-0.5814
0.7836
-2.0568
-0.1252
-0.7736
0.2199
-0.0308
1.0987
-0.3793
0.1787
0.2482
0.1089
0.1986
0.3043
0.1662
-0.0526
0.1259
-0.5224
0.371
-0.125
-0.0359
0.4173
-1.209
0.108
-0.0121
0.6731
-0.953
1.2712
0.2804
0.9778
-0.8012
-0.1299
0.1951
0.2964
-0.4761
1.3012
0.424
-0.251
0.9498
-1.9421
1.408
-1.5055
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0004C0C600000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
74.3358
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
40.679
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10299344 5 18412268337065274932
11089746 13 8718537303618060368
117089 54 18119255201851808267
11963148 33 18336820884835724690
12107183 9 18270692970117888697
12166972 35 17967535670892648612
12592606 108 18341046402915944351
12596602 18 17561081427533866920
12633257 1 15769770303829617137
12760667 363 18343014498290378565
13103583 49 17847067670694848385
13402501 40 18335422378452502115
13533116 47 18341050838747034961
13631057 29 18410854322510643160
13685833 64 18409730681387268017
13690498 29 18113611271094955789
14123256 34 18410858762968574919
14251764 30 18410291436965751081
14420673 8 18410295835423939571
14931854 50 17894904122905202643
15183329 4 17967813838660333770
15510800 12 17895482552448046291
15537594 2 18272365395041342174
16110190 28 18131067155766339277
17134984 74 17312820498317876098
17492 89 18194681463108904150
17780758 139 17917992737823290857
19246450 95 18129118753719213593
20028762 73 18341612595053112094
20165401 70 18196933499694878279
21054139 6 18260830342189275418
21197605 99 18413108373272586062
21267235 1 18410859866822779220
21774942 28 12180109961340499406
22149856 69 18272376352104560968
22950370 63 18412263921686439929
23424784 1240 18130231441510457974
23522609 53 18122659177438674941
23569917 315 18265618681433725634
25269216 80 16298387964140350685
2748736 6 9007062344311454479
3004659 81 18113614599135427472
351380 3 18412542106733642908
4107672 100 17604422999903191021
439807 62 18333731303898885775
4461854 278 17989212572404404278
46194498 28 17386283306691771228
465052 167 18272653446193361516
474113 269 18058719347807297279
5104073 3 17988925582831798385
54039377 194 18411141325115577710
59682541 35 18272641373509609288
59682541 52 13623798398539679480
636775 8 18341339903679836422
6431902 208 18409728443661918415
7970288 3 18410571803709316259
999808 66 18187937200713011907
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
456.47
21.63
3.06
0.82
1.65
0.44
-0.07
-16.48
1.28
-1.04
0.17
-0.86
-0.1
-0.24
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
956.603
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
259
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
128
152
31
198
85
2
117
229
288
137
285
242
114
47
90
263
52
84
240
245
130
129
13
283
258
190
251
123
215
221
72
225
255
259
193
227
122
150
262
39
252
248
246
95
10
247
212
206
124
238
151
181
166
8
116
74
100
277
132
223
87
182
34
264
69
146
94
64
162
256
126
3
112
183
230
163
75
66
4
208
234
133
80
141
266
167
109
204
22
54
191
287
278
184
187
218
18
249
136
155
148
156
125
24
197
89
273
19
58
172
134
127
96
145
203
49
107
62
73
160
165
173
115
284
108
186
241
26
161
175
171
257
40
202
149
92
261
228
179
254
180
219
164
194
38
201
244
253
220
43
81
36
281
217
222
14
211
213
239
147
279
143
41
144
207
60
260
50
7
16
57
6
45
195
118
214
102
71
170
78
65
9
120
272
83
44
79
111
20
188
37
70
63
216
157
174
275
91
189
101
30
140
59
200
177
56
168
154
138
176
93
235
158
119
185
42
33
86
105
121
77
55
51
196
271
21
169
61
270
12
99
32
135
265
233
27
159
82
286
236
280
25
250
28
205
274
267
48
131
269
276
268
88
97
104
17
106
226
5
142
113
46
192
224
98
178
53
210
15
209
243
67
23
237
35
139
282
199
231
68
232
76
29
103
153
11
110
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
32
1 -0.18
10 -0.14
11 0.28
12 0.28
13 -0.15
14 -0.15
15 0.08
16 0.14
17 -0.15
18 0.18
19 -0.15
2 -0.36
20 -0.15
21 0.78
22 0.13
23 -0.15
24 -0.15
29 0.15
3 -0.43
30 0.15
31 0.37
35 0.15
36 0.15
37 0.15
38 0.15
39 0.15
4 -0.57
5 -0.52
6 -0.52
7 -0.55
8 0.91
9 0.12
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 2 acceptor
1 4 acceptor
1 5 acceptor
1 5 anion
1 6 acceptor
1 7 donor
6 15 19 20 22 23 24 rings
6 9 10 13 14 17 18 rings
24
0
0
0
0
0
0
0
1
2