Bookmark and Share

Compound Summary for: CID 3002190

telithromycin

Also known as: Ketek, HMR-3647, DSSTox_CID_26455, DSSTox_RID_81629, DSSTox_GSID_46455, Levviax, HMR3647, HMR 3647, 191114-48-4
Molecular Formula: C43H65N5O10   Molecular Weight: 812.0037   InChIKey: LJVAJPDWBABPEJ-PNUFFHFMSA-N
Telithromycin, a semi-synthetic erythromycin derivative, belongs to a new chemical class of antibiotics called ketolides. Ketolides have been recently added to the macrolide-lincosamide-streptogramin class of antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering with bacterial protein synthesis. Telithromycin binds to the 50S subunit of the 70S bacterial ribosome and blocks further peptide elongation. Binding occurs simultaneously at to two domains of 23S RNA of the 50S ribosomal subunit, domain II and V, where older macrolides bind only to one. It is used to treat mild to moderate respiratory infections.   From: DrugBank
Show subcontent titlesTable of Contents
Identification
Related Records
show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)
Use and Manufacturing
Pharmacology
Biomedical Effects and Toxicity
Environmental Fate and Exposure Potential
Exposure Standards and Regulations
Literature
Patents
Biomolecular Interactions and Pathways
Biological Test Results
Classification
Chemical and Physical Properties
_ _