Debrisoquin - Compound Summary (CID 2966)
Also known as: Debrisoquine, Debrisochinum, Isocaramidine, Tendor, Declinax, Equitonil, Debrisoquina, Debrisoquinum, Debrisoquinum [INN-Latin]
Molecular Formula: C10H13N3   Molecular Weight: 175.23032   InChIKey: JWPGJSVJDAJRLW-UHFFFAOYSA-N
An adrenergic neuron-blocking drug similar in effects to GUANETHIDINE. It is also noteworthy in being a substrate for a polymorphic cytochrome P-450 enzyme. Persons with certain isoforms of this enzyme are unable to properly metabolize this and many other clinically important drugs. They are commonly referred to as having a debrisoquin 4-hydroxylase polymorphism.   From: MeSH
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