2812356 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 8 8 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 3 4 4 4 5 5 5 6 6 7 8 8 8 8 9 9 10 10 11 11 11 12 12 13 15 15 16 16 17 17 18 18 19 20 20 21 21 23 23 24 24 26 26 26 27 27 28 28 29 29 30 30 31 31 32 14 25 26 9 11 13 10 12 14 14 16 43 13 18 22 9 10 33 34 35 36 37 38 12 39 40 41 42 15 17 22 20 21 19 44 19 45 46 23 47 24 48 25 49 25 50 27 51 52 28 29 30 53 31 54 32 55 32 56 57 2 1 1 1 1 1 1 1 1 1 1 1 1 2 3 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 2 1 2 1 1 1 1 1 1 2 1 2 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 1 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 3.4767 3.3016 5.4078 4.9078 5.0372 6.2738 2.8097 6.5312 6.3087 5.9078 4.5068 4.2843 5.4078 4.4739 4.5417 4.6033 4.5417 6.2738 5.4078 5.1666 3.6061 3.6757 4.7327 3.1722 3.7355 3.865 3.4311 3.9944 2.4339 3.5605 2 2.5633 7.0898 6.9178 6.4467 6.9287 6.4664 5.7698 3.8868 4.3688 3.8977 3.7257 5.6554 4.0048 6.8107 5.4078 5.7849 3.2568 5.082 2.554 4.3088 4.3684 4.6127 2.0846 3.9098 1.3817 2.2943 -0.8591 3.4963 -4.0254 -1.8348 -0.1076 -5.5254 -4.5254 -2.6166 -3.5916 -1.8348 -3.5916 -2.6166 -5.0254 -0.9338 -5.5254 0.7934 -6.5254 -6.5254 -7.0254 1.6196 0.8681 -5.0254 2.5206 1.7691 2.5953 4.3225 5.2235 6.0497 5.2982 6.9507 6.1992 7.0254 -2.8856 -2.1319 -4.196 -3.5916 -1.5658 -1.2303 -3.5916 -4.196 -2.1319 -2.8856 -0.1539 -6.8354 -6.8354 -7.6454 1.5733 0.3558 3.0329 1.8154 3.8896 4.6844 6.0034 4.786 7.463 6.2455 7.584 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 6 6 13 15 16 16 17 18 20 21 23 24 27 27 28 29 30 31 13 18 15 17 20 21 19 19 23 24 25 25 28 29 30 31 32 32 0 Compound Canonicalized 5 2011.04.04 1 Compound Complexity 7 E_COMPLEXITY 3.402 Cactvs xemistry.com 2012.05.21 636 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.402 Cactvs xemistry.com 2012.05.21 5 Count Hydrogen Bond Donor 5 E_NHDONORS 3.402 Cactvs xemistry.com 2012.05.21 1 Count Rotatable Bond 5 E_NROTBONDS 3.402 Cactvs xemistry.com 2012.05.21 5 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.402 Cactvs xemistry.com 2012.05.21 00000371E07BB0000000000000000000000000000000000000003C608000058000000001D000001E00100000000C0CE19A063DF693C81400B80636677400A2882931222009D8203E6C988CE6E2C4F99B963828ECD613C8E82FB0C0200E00400000000000000080000000000000000000000000 IUPAC Name Allowed 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(4-benzyloxyphenyl)-4-(3-cyano-2-pyridyl)-1,4-diazepane-1-carboxamide IUPAC Name CAS-like Style 1 2.1.0 LexiChem openeye.com 2012.05.21 4-(3-cyano-2-pyridinyl)-N-(4-phenylmethoxyphenyl)-1,4-diazepane-1-carboxamide IUPAC Name Preferred 1 2.1.0 LexiChem openeye.com 2012.05.21 4-(3-cyanopyridin-2-yl)-N-(4-phenylmethoxyphenyl)-1,4-diazepane-1-carboxamide IUPAC Name Systematic 1 2.1.0 LexiChem openeye.com 2012.05.21 4-(3-cyanopyridin-2-yl)-N-(4-phenylmethoxyphenyl)-1,4-diazepane-1-carboxamide IUPAC Name Traditional 1 2.1.0 LexiChem openeye.com 2012.05.21 N-(4-benzoxyphenyl)-4-(3-cyano-2-pyridyl)-1,4-diazepane-1-carboxamide InChI Standard 1 1.0.4 InChI iupac.org 2012.05.21 InChI=1S/C25H25N5O2/c26-18-21-8-4-13-27-24(21)29-14-5-15-30(17-16-29)25(31)28-22-9-11-23(12-10-22)32-19-20-6-2-1-3-7-20/h1-4,6-13H,5,14-17,19H2,(H,28,31) InChIKey Standard 1 1.0.4 InChI iupac.org 2012.05.21 MLZSFSOSEMZUJD-UHFFFAOYSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2012.05.21 3.5 Mass Exact 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 427.200825 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 C25H25N5O2 Molecular Weight 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 427.4983 SMILES Canonical 1 1.7.6 OEChem openeye.com 2012.05.21 C1CN(CCN(C1)C(=O)NC2=CC=C(C=C2)OCC3=CC=CC=C3)C4=C(C=CC=N4)C#N SMILES Isomeric 1 1.7.6 OEChem openeye.com 2012.05.21 C1CN(CCN(C1)C(=O)NC2=CC=C(C=C2)OCC3=CC=CC=C3)C4=C(C=CC=N4)C#N Topological Polar Surface Area 7 E_TPSA 3.402 Cactvs xemistry.com 2012.05.21 81.5 Weight MonoIsotopic 7 2.1 PubChem ncbi.nlm.nih.gov 2012.05.21 427.200825 32 0 0 0 0 0 0 0 1 2