2803334 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 8 8 8 8 8 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 4 5 6 6 6 7 7 7 7 8 8 9 9 10 10 11 11 12 12 12 13 15 16 17 18 19 19 20 20 21 22 22 22 23 23 23 24 24 24 25 25 25 13 22 15 23 17 24 18 25 14 8 14 30 8 9 26 27 28 29 10 11 13 31 16 32 14 17 18 15 16 33 19 20 21 34 21 35 36 37 38 39 40 41 42 43 44 45 46 47 48 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 2 1 2 1 1 1 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 2.2874 4.2295 -0.4105 -3.6164 -0.2204 -1.1268 1.0047 -0.2741 1.8654 1.6754 2.8307 -1.9897 2.471 -1.0413 3.4464 3.6262 -1.6364 -3.2504 -2.5438 -4.1577 -3.8043 1.2696 3.7538 -0.1384 -4.2499 0.7534 1.5818 -0.8549 -0.0365 -1.7881 0.9068 2.9764 4.384 -2.3403 -5.1411 -4.5113 1.4958 0.2771 1.2578 3.0805 4.612 3.2426 0.8629 -0.1204 -0.8234 -3.6361 -5.2332 -4.3852 -1.4238 -1.3365 -1.8892 1.4634 0.6619 2.0649 3.1831 3.2005 1.9728 0.8244 2.0309 -0.1873 -0.2945 0.8563 -0.2506 0.9121 -1.5302 0.1574 -2.5283 -0.8407 -2.1836 -1.3864 -2.2693 -3.2853 2.0779 3.2208 4.0948 4.0994 3.2194 2.1595 0.8514 2.931 0.9531 -3.591 -0.5799 -2.9599 -0.6505 -1.238 -2.3684 -2.9807 -2.8184 -1.7699 -3.39 -3.7631 -3.7835 1.986 1.6286 3.1397 1.6135 -0.3727 -0.8616 0.3691 -1.5378 0.0706 0.6359 -0.1979 0.3683 1.1208 -0.6247 -0.2545 0.874 -0.6266 -0.1221 -0.8714 -0.3868 0.2332 -0.0317 0.5885 0.456 2.6119 -1.341 -0.9622 -0.7507 1.7041 0.4356 0.0337 -1.2676 0.8349 1.8852 -1.215 -1.6492 -0.1029 0.9699 0.7339 3.391 2.174 3.0962 -0.8564 -1.7381 -2.1708 -1.3885 0.0231 -1.657 -1.6524 -0.9218 -0.5273 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 002AC6860000002C Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 106.5735 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 40.612 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 12011746 2 18267863878789666589 12553582 1 18268985552475089644 12596599 1 18412270506007942194 12633257 1 18191298291441311803 13140716 1 18338222804408269841 13224815 77 17822561819547587699 13583140 156 14189034322618547967 14178342 30 17765415926876115464 14223421 5 18050845817031401853 14866123 147 17479187366245306906 16752209 62 18270385205155118183 17093844 170 18127127468618738262 17349148 13 17917428783137269797 19078846 21 18262221266667479978 19591789 44 18411985766898569983 19930381 70 18341057384076785990 20442098 301 18125434473819647465 20600515 1 18199484189601577228 20691752 17 17167857595139890422 23559900 14 18341615850004670550 7097593 13 18124596633253988173 7832392 63 18053946431221291646 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 480.16 7.62 3.91 1.42 1.89 0.47 -0.66 -1.39 0.65 0.25 0.56 -0.91 -0.67 0.52 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1014.023 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 269.4 Conformer RMSD 7 2009.12.11 1 Diverse Conformer ID List 6 2012.02.08 44 18 30 40 26 33 8 38 43 29 2 27 10 57 48 19 46 6 1 51 47 56 15 21 7 9 45 20 4 42 16 13 3 17 49 5 11 55 32 54 39 36 41 24 52 37 25 34 28 31 14 50 58 23 53 22 35 12 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 32 1 -0.36 10 -0.15 11 -0.15 12 0.09 13 0.08 14 0.54 15 0.08 16 -0.15 17 0.08 18 0.08 19 -0.15 2 -0.36 20 -0.15 21 -0.15 22 0.28 23 0.28 24 0.28 25 0.28 3 -0.36 30 0.37 31 0.15 32 0.15 33 0.15 34 0.15 35 0.15 36 0.15 4 -0.36 5 -0.57 6 -0.73 7 0.14 8 0.3 9 -0.14 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 9 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 8 1 1 acceptor 1 2 acceptor 1 3 acceptor 1 4 acceptor 1 5 acceptor 1 6 donor 6 12 17 18 19 20 21 rings 6 9 10 11 13 15 16 rings 25 0 0 0 0 0 0 0 1 2