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Compound Summary for: CID 2756

Cimetidine

Also known as: Tagamet, Cimetag, Eureceptor, Cimetidina, Cimetidinum, Cimetum, Tametin, Ulcedine, Ulcimet
Molecular Formula: C10H16N6S   Molecular Weight: 252.33924   InChIKey: AQIXAKUUQRKLND-UHFFFAOYSA-N
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRINS output. It also blocks the activity of CYTOCHROME P-450 which might explain proposals for use in NEOADJUVANT THERAPY.   From: MeSH
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