Molecular Formula: C
10H
16N
6S
Molecular Weight: 252.33924
InChIKey: AQIXAKUUQRKLND-UHFFFAOYSA-N
A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRINS output. It also blocks the activity of CYTOCHROME P-450 which might explain proposals for use in NEOADJUVANT THERAPY.
From: MeSH