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Compound Summary for: CID 2724385     Try the new version summary page


Also known as: 12beta-Hydroxydigitoxin; 20830-75-5; CHEBI:4551; Lanoxicaps; Lanoxin; NCGC00090797-03; ST069334; DSSTox_CID_2934
Molecular Formula: C41H64O14   Molecular Weight: 780.93846   InChIKey: LTMHDMANZUZIPE-PUGKRICDSA-N
A cardiotonic glycoside obtained mainly from Digitalis lanata; it consists of three sugars and the aglycone DIGOXIGENIN. Digoxin has positive inotropic and negative chronotropic activity. It is used to control ventricular rate in ATRIAL FIBRILLATION and in the management of congestive heart failure with atrial fibrillation. Its use in congestive heart failure and sinus rhythm is less certain. The margin between toxic and therapeutic doses is small. (From Martindale, The Extra Pharmacopoeia, 30th ed, p666)   From: MeSH
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