258201
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
17
8
8
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
4
4
5
5
6
6
6
7
7
7
8
8
8
9
9
10
10
10
11
11
11
5
8
9
28
5
6
7
12
13
14
10
15
16
17
18
19
9
20
21
11
22
23
24
25
26
27
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
4
5
6
7
12
3
1
9
3
8
11
22
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
-2.5937
0.1168
-3.5035
2.5412
1.2169
2.6452
2.7394
-1.1216
-2.2544
2.5347
-2.3211
3.3548
1.2289
1.0973
1.8729
3.6124
1.9801
3.722
2.6863
-1.1588
-1.2245
-2.1216
3.2526
1.5289
2.7439
-3.1561
-1.3996
-4.1985
2.0398
-0.6249
-0.9054
-0.4705
-0.6836
0.9119
-1.5631
-0.7719
-0.674
2.0733
0.6685
-0.5588
-1.6691
0.0661
1.0201
0.9861
-1.508
-1.4675
-2.5578
-1.7525
-0.0164
-1.4615
1.969
2.1484
3.0165
0.6773
0.8688
-0.8843
-0.071
-0.0249
-0.3412
-0.1764
-0.9219
0.4963
0.8804
-0.7066
0.3109
-0.481
1.0354
-0.908
-1.4045
-1.7119
1.2675
1.0092
1.6677
1.355
0.4254
-1.1977
-1.4941
1.0626
-1.3004
-0.9046
0.0341
1.743
1.5903
0.3386
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0003F09900000016
Energy
MMFF94 NoEstat
7
1.6.0
Szybki
openeye.com
2012.01.18
13.8417
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.01.18
25.371
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
12162725 195 18412825780728210923
12696612 119 18408889529338455140
12932764 1 18335434430051177967
13618510 140 18341618100673619364
15775835 57 18272380809716189224
17041 49 18263360279220220850
17041 50 18199481960834472404
170605 34 18269279130796026420
17802600 8 18272364308509762776
17834069 15 18190178992630235852
19973954 147 18412549786071981533
201361 129 18260272949628064444
20279233 1 14851605487808109146
20671657 1 18336270149683838436
21028194 46 17989208152739714974
21524375 3 18054231200786285748
22959321 28 18267316510697896713
230 275 18340486763643621896
3248919 1 17632297822209600327
Shape
Multipoles
8
1.8.1
OEShape
openeye.com
2012.01.18
216.51
5.99
2.04
0.97
1.29
1.13
-0.06
0.62
-0.68
-0.37
0.06
-0.08
-0.09
-0.56
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.01.18
383.771
Shape
Volume
7
1.8.1
OEShape
openeye.com
2012.01.18
142.2
Conformer
RMSD
7
2009.12.11
0.6
Diverse Conformer
ID List
6
2012.02.08
22
312
83
336
352
305
60
324
286
84
73
256
319
157
368
261
330
345
1
17
259
74
343
89
348
316
370
28
192
226
292
199
63
304
178
350
338
53
299
317
64
377
104
384
8
272
375
131
172
173
335
36
372
318
18
376
82
373
309
75
360
242
314
244
49
289
135
175
174
322
69
380
323
102
279
291
47
138
43
193
328
195
65
161
263
275
85
371
48
361
366
236
105
268
251
369
169
205
181
378
187
357
4
79
342
106
280
77
58
255
327
11
76
180
253
170
379
347
346
30
3
203
247
208
306
266
140
143
144
332
269
355
21
362
112
171
270
46
297
51
155
156
230
367
108
308
101
245
354
277
310
118
258
225
38
356
204
16
252
113
250
262
152
298
72
382
337
163
26
94
166
260
218
359
2
12
326
265
23
344
383
201
35
159
227
274
114
237
210
293
374
148
107
93
198
130
341
177
91
333
56
162
287
86
214
234
220
273
133
41
246
119
151
71
381
139
243
248
37
329
211
45
271
24
209
116
120
358
88
239
167
365
142
33
313
194
42
6
202
231
240
97
57
117
302
137
134
325
223
98
340
191
126
50
300
363
132
109
219
19
301
276
229
31
311
267
334
103
197
233
212
364
127
34
122
123
196
87
189
183
96
200
307
39
149
213
190
283
52
67
145
154
351
13
295
61
224
331
92
15
110
100
257
254
7
353
90
206
288
216
182
70
158
9
264
281
176
238
164
125
40
217
284
115
128
282
80
20
146
241
68
186
285
32
165
62
185
339
179
10
81
124
25
349
14
232
235
221
278
29
27
215
129
66
121
168
55
249
141
44
207
150
136
78
228
303
188
99
59
320
321
160
5
290
95
184
296
294
111
153
315
54
222
147
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
8
1 -0.29
11 0.29
2 -0.56
28 0.4
3 -0.68
5 0.28
8 0.28
9 0.28
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
5
1 10 hydrophobe
1 2 acceptor
1 3 acceptor
1 3 donor
1 7 hydrophobe
11
2
0
2
0
0
0
0
1
1