Molecular Formula: C
30H
34O
13 Molecular Weight: 602.58316
InChIKey: VJKUPQSHOVKBCO-SHBYWDFQSA-N
A noncompetitive antagonist at GABA-A receptors and thus a convulsant. Picrotoxin blocks the GAMMA-AMINOBUTYRIC ACID-activated chloride ionophore. Although it is most often used as a research tool, it has been used as a CNS stimulant and an antidote in poisoning by CNS depressants, especially the barbiturates.
From: MeSH