24770228 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 16 16 16 16 16 16 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 8 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 4 5 5 6 7 8 9 9 10 11 12 13 13 14 15 16 17 18 19 20 21 22 23 23 24 25 26 27 28 29 30 31 32 32 33 33 34 35 36 37 38 38 39 40 41 42 43 44 45 45 46 47 47 48 48 49 50 50 51 52 53 54 54 54 55 55 55 56 56 56 57 57 57 58 58 58 59 59 59 60 60 60 61 61 61 62 62 62 63 63 63 64 64 64 65 65 65 66 66 66 67 67 67 68 68 68 69 69 69 70 70 70 71 71 71 72 72 72 73 73 73 74 74 74 75 75 75 76 76 76 77 77 77 78 78 78 79 79 79 80 80 80 81 81 81 82 82 82 83 83 83 84 84 84 85 85 85 86 86 86 87 87 87 88 88 88 89 89 89 90 90 90 90 91 91 92 92 92 93 93 93 95 95 95 96 96 96 98 98 98 99 99 99 100 100 102 102 103 103 103 104 104 104 105 106 106 106 107 107 108 108 109 109 109 109 110 110 112 112 112 113 113 114 114 114 114 115 115 116 116 116 117 117 118 118 119 119 119 120 120 120 121 122 122 122 123 123 123 127 127 127 129 129 129 130 130 130 131 131 131 132 132 134 134 134 135 135 136 136 136 137 137 137 139 140 140 140 141 141 142 142 142 144 145 145 146 146 147 147 147 148 148 148 150 150 152 152 153 153 154 154 154 155 155 157 157 157 158 158 159 159 160 160 161 161 161 162 163 163 163 164 164 164 165 168 168 168 169 169 169 172 172 172 174 174 174 175 175 175 177 177 179 179 180 180 181 181 182 182 182 183 183 184 184 185 185 185 186 186 187 187 188 190 190 190 191 191 192 192 192 193 193 193 194 194 196 197 197 197 198 198 198 199 199 199 200 200 201 201 202 202 203 203 205 205 205 206 206 206 207 207 207 208 211 211 212 212 213 213 217 217 218 218 220 220 220 222 222 223 223 225 225 226 228 228 228 229 229 4 132 3 141 160 190 6 153 202 94 97 100 258 101 105 111 126 323 124 125 126 128 133 138 139 143 144 150 372 149 151 156 166 167 170 171 173 183 404 184 405 176 178 189 195 203 416 204 208 209 210 214 215 219 421 216 221 422 225 423 219 230 424 224 226 227 91 97 238 94 95 240 96 105 248 101 103 249 111 120 271 110 125 272 113 144 290 115 139 291 119 138 293 128 131 296 124 140 297 143 147 311 133 163 313 142 151 316 145 149 317 136 167 320 134 170 319 148 156 326 154 166 339 162 165 340 161 176 347 164 178 348 155 189 350 172 173 353 171 198 365 168 208 367 182 204 376 192 210 387 195 207 390 191 226 395 197 216 396 206 209 397 213 215 400 224 229 415 214 417 418 227 419 420 91 92 93 231 94 232 98 233 234 235 236 237 99 101 239 97 100 241 242 243 244 102 245 246 104 247 107 108 106 111 250 251 252 253 113 126 254 255 117 256 118 257 110 112 259 260 124 261 122 123 262 263 264 115 116 265 266 128 267 129 130 268 121 269 121 270 125 127 273 132 133 274 275 276 277 278 279 280 281 135 282 283 284 285 286 287 288 289 141 143 292 294 295 137 149 298 158 159 138 153 299 146 300 301 145 151 302 303 304 305 150 156 306 155 307 308 152 165 157 171 309 160 166 310 175 312 162 179 314 315 169 173 318 321 322 177 324 325 180 327 181 328 329 330 167 183 331 186 178 332 333 174 176 334 335 170 185 336 187 337 338 184 195 341 193 342 343 344 345 346 200 201 194 349 188 351 188 352 189 199 354 355 356 205 357 214 358 359 196 360 211 212 361 191 362 363 209 364 203 204 366 219 368 369 196 370 371 202 215 373 210 374 375 227 377 378 217 379 218 380 381 382 220 383 384 385 386 216 225 388 224 228 389 213 222 391 223 392 393 394 221 398 221 399 401 402 403 230 406 230 407 408 409 229 410 411 412 413 414 1 1 1 1 1 1 1 1 1 2 2 1 1 2 2 2 1 1 2 2 2 2 2 2 2 2 2 1 1 2 2 2 2 2 2 2 2 1 1 1 1 2 2 2 2 1 1 2 2 2 2 2 2 1 1 2 1 1 1 1 2 1 1 2 2 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 1 1 1 2 1 1 1 1 1 1 2 1 1 1 1 1 1 1 1 1 1 1 90 91 93 92 231 2 1 91 54 90 94 232 1 1 95 55 99 101 239 1 1 96 56 100 97 241 2 1 100 9 96 104 247 1 1 103 57 106 111 250 1 1 110 59 109 124 261 1 1 115 61 114 128 267 1 1 119 62 127 125 273 2 1 120 58 132 133 274 1 1 131 63 141 143 292 1 1 134 70 137 149 298 1 1 136 69 153 138 299 2 1 142 67 150 156 306 1 1 147 65 157 171 309 1 1 148 71 160 166 310 1 1 150 23 142 175 312 1 1 154 72 169 173 318 1 1 161 74 183 167 331 2 1 164 75 174 176 334 1 1 168 79 185 170 336 2 1 172 77 184 195 341 1 1 182 80 199 189 354 2 1 184 33 172 205 357 1 1 191 83 190 209 364 1 1 192 81 203 204 366 1 1 197 84 202 215 373 1 1 203 38 192 220 383 1 1 206 85 225 216 388 2 1 207 82 228 224 389 2 1 1 5 255 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424 53.9467 19.5839 20.5179 54.4436 26.6777 25.8437 34.2875 25.2412 21.0372 42.7387 16.6642 49.6004 49.439 29.7158 30.3358 48.6 15.7908 51.2428 29.4724 14.6886 14.8447 9.5656 27.0275 15.062 27.7296 24.7528 25.1878 33.3589 16.8402 8.2189 34.2345 36.618 40.9974 39.9825 45.9656 4.7806 42.6923 2.6092 2.8723 19.6871 49.0696 4.0652 19.0647 23.0643 44.213 33.651 6.6107 37.504 42.5316 34.838 49.5661 54.047 4.7865 28.294 36.9195 19.7787 44.6401 50.5475 29.3 12.3753 15.8643 28.9742 17.2263 28.3382 13.0423 48.7558 26.2708 15.7555 30.4317 16.9205 23.4886 28.2421 15.8864 37.1718 43.3022 6.955 36.8699 7.3894 19.1389 4.1555 4.3062 44.5988 53.9349 28.9301 44.1074 21.9913 50.5193 17.4624 3.0545 31.0252 31.208 30.0824 31.7853 34.0958 39.6417 22.5414 25.3924 29.8997 40.274 22.0372 42.2266 41.2611 46.8503 22.533 17.1405 47.7073 41.8934 41.6158 29.9874 29.1183 48.8282 30.8504 14.6619 15.2668 16.1872 14.4679 42.8805 42.6029 29.2271 51.9857 43.2352 31.7194 30.8443 28.7955 29.3365 48.5821 30.224 16.6444 13.5476 14.5894 17.9203 53.1238 50.4127 16.3995 30.7909 28.0621 15.5102 28.5831 15.6826 27.7564 18.7118 25.3987 15.3901 10.311 15.6461 15.4615 10.908 22.4913 16.0084 26.0431 27.0623 14.6293 27.4225 31.1561 8.4963 24.4647 10.0316 30.3609 31.7878 21.494 34.9893 14.8933 47.017 41.3308 16.2369 25.341 32.7417 18.3049 31.232 17.5601 9.0154 39.5943 34.0448 42.0514 25.703 39.2865 9.1764 45.1984 13.662 30.9278 32.3547 4.7702 35.6335 40.0027 17.6937 14.19 32.1335 31.9247 5.7075 54.608 54.4377 3.922 43.0121 12.9587 42.1819 13.2227 23.9807 6.0515 3.9083 8.3 9.1976 24.9383 2.9394 3.8715 39.4164 38.9996 46.8129 20.0444 49.2555 5.0192 32.9591 32.2094 21.002 18.0736 22.9913 33.9385 7.4447 8.3423 43.2522 2.2871 7.4659 33.8606 33.1109 48.7951 38.504 53.1062 3.9164 47.5057 51.9627 33.9365 30.9119 31.4913 29.4624 29.9804 32.1882 32.2565 31.3824 28.2712 39.7411 37.1073 22.5373 30.5092 29.7864 29.2901 40.4781 39.7329 21.7299 19.5478 45.0166 47.1507 23.0714 22.8404 21.9945 48.0972 47.3003 41.6735 41.2238 20.7246 29.5918 30.3888 29.7383 30.8541 14.6193 15.0178 14.8136 15.6047 15.6211 14.3926 43.2725 42.8229 51.0683 29.9163 29.7869 52.4473 43.8472 31.4127 32.2582 32.0261 31.4643 30.8405 30.2243 30.0684 30.788 13.3051 12.977 13.7901 15.2048 14.6647 13.974 11.9636 15.2644 17.3531 29.561 53.7315 52.54 16.7497 28.8674 16.2318 27.3709 14.8951 15.3268 27.9565 27.2798 18.1505 19.0539 25.548 15.129 16.2657 10.5867 22.4913 12.6469 26.4426 49.2581 28.0276 26.9761 26.6129 15.1458 30.7389 16.4162 30.7971 8.2472 9.0028 49.4279 9.6231 10.42 23.5789 29.7429 32.0543 21.0974 21.5843 35.6075 47.247 46.5277 41.9505 16.8349 18.4064 30.615 31.0648 28.2179 16.2278 39.2684 41.5505 42.3242 25.1199 25.4921 26.286 37.5875 43.7637 13.4983 6.4108 30.6613 32.9727 37.0565 4.1502 35.0972 35.8467 40.2559 17.1698 17.2763 14.3537 32.2762 55.1386 53.988 55.2755 6.8559 3.1197 18.8355 43.0781 43.6307 12.359 12.7867 27.427 23.7958 5.4362 6.6177 3.543 3.2986 3.6915 8.2868 9.741 25.429 24.7168 3.3439 38.9141 39.0528 39.9186 3.6974 39.0028 46.7827 44.9742 32.912 31.6976 21.2022 21.1368 54.5384 28.7313 43.9709 6.9013 8.3555 21.9461 1.8172 1.8827 2.757 37.0174 41.2506 34.3724 33.158 39.0877 38.3994 47.0586 47.9353 47.9528 52.2959 51.4073 51.0394 2 17.698 16.848 2.5151 3.0596 44.6598 6.0673 37.1967 34.885 6.2812 -23.2945 -23.6517 3.4094 -11.6708 -11.119 26.4145 26.6007 25.8655 23.1822 23.7189 17.2841 19.336 -20.1624 -16.8057 17.8207 -21.1816 8.7705 -13.5031 -17.9509 -21.5856 18.1082 -23.8836 -14.5578 -22.9386 -24.6093 -25.5415 -10.4802 -11.644 -15.4237 -25.3738 -8.4556 -23.6555 -4.7005 1.74 10.4287 -22.1589 -0.2404 1.584 -9.7606 -2.3143 -7.3853 -9.8207 -9.2636 -1.0981 -6.0761 -15.4441 -4.7366 -0.6822 -27.5081 -16.2748 -8.4141 9.2935 25.8867 24.7108 24.0785 20.6893 14.2954 -17.8415 19.4991 -18.8249 -14.8807 -21.474 -20.6607 -19.0204 6.9523 -22.805 -15.8482 -11.4409 -13.1068 -23.8691 -24.8338 -10.9519 -5.9619 0.1917 12.6873 -23.6756 -12.4003 -11.119 4.4445 -4.2594 -19.6699 -5.281 -8.6333 -4.364 -10.2609 -13.2881 -9.1628 9.3076 26.8099 25.8267 27.1432 27.4597 25.433 23.6697 25.0068 25.6122 28.1264 24.4444 25.8704 22.3232 24.2841 18.7895 26.7388 22.8396 19.3049 25.0588 23.3491 -19.3196 -18.8249 16.6488 -18.8143 21.3064 -20.1624 -19.7713 -19.5609 24.8985 23.1889 -15.8482 11.7604 23.9636 -19.3091 -17.8144 -19.7713 -16.8422 18.8205 -15.9273 -20.6607 -19.9521 -18.5684 -22.1939 9.0772 9.3282 -13.9604 -15.1035 -13.1068 -13.5031 -13.9604 -17.8415 -21.474 -22.805 -23.2945 -20.7474 17.4416 -16.8422 -12.5043 -17.0355 -23.9421 -14.8807 -24.0592 -22.1939 -11.9606 -12.3381 -24.7798 15.161 -23.6517 -17.5171 -14.2006 -15.1825 -23.8691 -7.8663 -10.9961 4.6358 -1.9304 -11.8822 -24.5533 -9.6934 -11.6708 -25.7769 -12.3381 -14.8191 -22.64 -24.392 -2.6237 -24.9996 -3.9824 -16.9988 2.3813 -12.2142 -13.3769 -14.3588 7.2935 -8.6311 -23.5528 -10.8793 -10.2851 -26.2097 -13.4559 10.0533 0.4995 -2.4101 -1.3702 -2.3463 -11.5033 -21.2989 -10.5388 -10.4065 -9.811 7.8006 -17.4804 -15.9991 -10.6946 -1.1843 1.5439 -24.3629 -5.6102 -17.7746 -10.6946 -3.2969 -7.0854 -25.6454 -27.2068 -10.4065 -9.9543 -10.2609 -7.0338 -16.9621 -15.4808 -1.3755 -1.9423 -15.9624 -26.0782 -27.6396 -15.6379 -4.7417 -8.0752 8.8005 -18.4957 -10.7561 -27.0753 27.4194 26.6281 27.1375 26.5316 26.9884 27.8626 27.9309 26.5063 24.2816 25.3017 25.8568 28.2396 28.7359 28.0131 25.0298 24.747 25.3319 24.6539 21.1819 19.3319 26.4315 27.2773 27.0462 19.7869 19.7727 25.6385 22.8688 26.4009 -19.797 -19.7921 -18.8211 -19.4343 21.925 20.7987 -20.5855 -20.6823 -19.5185 -20.1764 25.3789 22.6092 14.6318 -17.9093 -15.5816 12.4741 23.8642 -19.8479 -19.6158 -18.7703 -17.8106 -17.1944 -17.8181 -16.5274 -16.1847 -19.3814 -20.1945 -20.5227 -18.6437 -17.9529 -18.493 19.9627 -18.9817 -22.8269 -14.6805 8.9546 8.8683 -21.8706 -20.9837 -13.3635 -13.6013 -13.4253 -14.0954 -22.0608 -21.0774 -23.0682 -22.288 -24.1312 -16.5001 -16.8648 -17.5658 -24.7921 -19.4979 -24.5333 6.5889 -12.2033 -12.7684 -23.3221 -15.7356 -25.2384 -12.746 -11.9418 15.7288 14.8034 19.9559 -17.9835 -18.0004 -24.4825 -14.1516 -15.7423 -24.3457 -23.2557 -7.9138 4.06 5.0166 -1.913 -12.0459 -11.0592 -25.7159 -26.3739 -25.4533 -10.4344 -23.4251 -2.9891 -3.1805 -24.7887 -25.5826 -25.2105 -6.4218 -0.2223 -12.8122 12.9844 -12.8171 -14.4078 -24.2668 7.2986 -8.9421 -9.2133 -24.1188 -10.5478 -11.3377 -9.6872 -12.9452 0.1787 0.5001 -2.2667 -12.7161 -1.651 -10.5784 -2.9628 -2.3884 -11.6605 -10.098 -24.3577 -11.2361 -9.7348 -9.5585 4.5403 7.9132 7.2197 -18.1002 -15.7005 -10.3157 -11.2737 -0.7144 -23.9994 -24.8652 -24.7264 -4.3763 -4.9902 -18.3939 -20.1633 -25.0272 -27.5567 -9.8197 -11.0116 -5.4228 -8.046 -3.7592 -17.2607 -14.861 -9.6425 -1.5378 -2.4122 -2.3467 -8.9298 -24.2215 -25.7283 -28.2578 -4.5325 -4.1305 -18.9253 -18.9428 -18.0661 -11.2789 -10.4804 -13.6256 -0.1251 -8.5892 -9.2456 9.002 9.9276 -1.5279 -15.7427 -4.1981 -28.1264 8 8 6 6 5 6 6 8 8 5 8 8 5 6 8 8 5 6 6 6 8 8 5 6 8 8 5 5 6 8 8 6 8 8 5 8 5 6 5 8 8 8 8 8 5 6 8 8 8 5 6 8 6 8 8 5 6 6 8 8 8 8 8 8 73 73 90 91 95 96 100 102 102 103 107 108 110 115 117 118 119 120 131 134 135 135 136 142 146 146 147 148 150 152 152 154 158 159 161 162 164 168 172 177 177 179 180 181 182 184 186 187 187 191 192 194 197 200 201 203 206 207 211 212 217 218 222 223 162 165 93 232 99 241 9 107 108 106 117 118 109 114 121 121 127 274 292 137 158 159 299 306 152 165 157 310 23 162 179 169 180 181 183 186 174 185 341 200 201 194 188 188 199 33 196 211 212 364 366 196 373 217 218 38 225 228 222 223 221 221 230 230 0 Compound Canonicalized 5 2021.05.07 1 Compound Complexity 7 E_COMPLEXITY 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 7820 Count Hydrogen Bond Acceptor 5 E_NHACCEPTORS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 53 Count Hydrogen Bond Donor 5 E_NHDONORS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 46 Count Rotatable Bond 5 E_NROTBONDS 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 31 Fingerprint SubStructure Keys 16 extended 2 E_SCREEN 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 00000371F07FFE007000000000000000000000000001600000003060C183000000005801F400001E04100800000D3CE5DE06BECEF2C99200A80335F75C0082802031222008D9A1BE6C980A76FEC2D1B394700866F611D8D807BFDFE28EA0000000000200004000000000040000000000000000 IUPAC Name Allowed 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1R,4S,7R,13S,16S,22S,25R,28S,34S,37S,46S,49S,52S,55S,58R,64S,67S,70R,73S,76S,82S,85R,88S,91S,94S)-13,37-bis(2-amino-2-oxo-ethyl)-52,73-dibenzyl-55-(carboxymethyl)-34,46,82,91-tetrakis[(1R)-1-hydroxyethyl]-4,67-bis(hydroxymethyl)-28,88-bis[(4-hydroxyphenyl)methyl]-16-(1H-indol-3-ylmethyl)-22,76-diisobutyl-94-methyl-49-[(1S)-1-methylpropyl]-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontaoxo-1a,2a,5a,6a,9a,10a-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.47,70.425,85]hendecahectan-64-yl]propanoic acid IUPAC Name CAS-like Style 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1R,4S,7R,13S,16S,22S,25R,28S,34S,37S,46S,49S,52S,55S,58R,64S,67S,70R,73S,76S,82S,85R,88S,91S,94S)-13,37-bis(2-amino-2-oxoethyl)-49-[(2S)-butan-2-yl]-55-(carboxymethyl)-34,46,82,91-tetrakis[(1R)-1-hydroxyethyl]-4,67-bis(hydroxymethyl)-28,88-bis[(4-hydroxyphenyl)methyl]-16-(1H-indol-3-ylmethyl)-94-methyl-22,76-bis(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontaoxo-52,73-bis(phenylmethyl)-1a,2a,5a,6a,9a,10a-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.47,70.425,85]hendecahectan-64-yl]propanoic acid IUPAC Name Markup 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1<I>R</I>,4<I>S</I>,7<I>R</I>,13<I>S</I>,16<I>S</I>,22<I>S</I>,25<I>R</I>,28<I>S</I>,34<I>S</I>,37<I>S</I>,46<I>S</I>,49<I>S</I>,52<I>S</I>,55<I>S</I>,58<I>R</I>,64<I>S</I>,67<I>S</I>,70<I>R</I>,73<I>S</I>,76<I>S</I>,82<I>S</I>,85<I>R</I>,88<I>S</I>,91<I>S</I>,94<I>S</I>)-13,37-bis(2-amino-2-oxoethyl)-52,73-dibenzyl-49-[(2<I>S</I>)-butan-2-yl]-55-(carboxymethyl)-34,46,82,91-tetrakis[(1<I>R</I>)-1-hydroxyethyl]-4,67-bis(hydroxymethyl)-28,88-bis[(4-hydroxyphenyl)methyl]-16-(1<I>H</I>-indol-3-ylmethyl)-94-methyl-22,76-bis(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontaoxo-1<I>a</I>,2<I>a</I>,5<I>a</I>,6<I>a</I>,9<I>a</I>,10<I>a</I>-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.4<SUP>7,70</SUP>.4<SUP>25,85</SUP>]hendecahectan-64-yl]propanoic acid IUPAC Name Preferred 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1R,4S,7R,13S,16S,22S,25R,28S,34S,37S,46S,49S,52S,55S,58R,64S,67S,70R,73S,76S,82S,85R,88S,91S,94S)-13,37-bis(2-amino-2-oxoethyl)-52,73-dibenzyl-49-[(2S)-butan-2-yl]-55-(carboxymethyl)-34,46,82,91-tetrakis[(1R)-1-hydroxyethyl]-4,67-bis(hydroxymethyl)-28,88-bis[(4-hydroxyphenyl)methyl]-16-(1H-indol-3-ylmethyl)-94-methyl-22,76-bis(2-methylpropyl)-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontaoxo-1a,2a,5a,6a,9a,10a-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.47,70.425,85]hendecahectan-64-yl]propanoic acid IUPAC Name Systematic 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1R,4S,7R,13S,16S,22S,25R,28S,34S,37S,46S,49S,52S,55S,58R,64S,67S,70R,73S,76S,82S,85R,88S,91S,94S)-13,37-bis(2-azanyl-2-oxidanylidene-ethyl)-49-[(2S)-butan-2-yl]-4,67-bis(hydroxymethyl)-55-(2-hydroxy-2-oxoethyl)-28,88-bis[(4-hydroxyphenyl)methyl]-16-(1H-indol-3-ylmethyl)-94-methyl-22,76-bis(2-methylpropyl)-34,46,82,91-tetrakis[(1R)-1-oxidanylethyl]-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontakis(oxidanylidene)-52,73-bis(phenylmethyl)-1a,2a,5a,6a,9a,10a-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.47,70.425,85]hendecahectan-64-yl]propanoic acid IUPAC Name Traditional 1 2.7.0 Lexichem TK OpenEye Scientific Software 2021.05.07 3-[(1R,4S,7R,13S,16S,22S,25R,28S,34S,37S,46S,49S,52S,55S,58R,64S,67S,70R,73S,76S,82S,85R,88S,91S,94S)-13,37-bis(2-amino-2-keto-ethyl)-52,73-dibenzyl-55-(carboxymethyl)-28,88-bis(4-hydroxybenzyl)-34,46,82,91-tetrakis[(1R)-1-hydroxyethyl]-16-(1H-indol-3-ylmethyl)-22,76-diisobutyl-2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80,83,86,89,92,95,98-tritriacontaketo-94-methyl-4,67-dimethylol-49-[(1S)-1-methylpropyl]-1a,2a,5a,6a,9a,10a-hexathia-3,6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51,54,57,60,63,66,69,72,75,78,81,84,87,90,93,96,99-tritriacontazatetracyclo[56.41.4.47,70.425,85]hendecahectan-64-yl]propionic acid InChI Standard 1 1.0.6 InChI iupac.org 2021.05.07 InChI=1S/C141H194N36O47S6/c1-12-66(6)112-137(220)164-86(40-73-23-17-14-18-24-73)127(210)163-91(46-111(198)199)129(212)168-94-58-225-227-60-96-133(216)167-93(57-179)131(214)169-95-59-226-228-62-98(171-132(215)92(56-178)166-124(207)81(35-36-110(196)197)154-103(189)51-151-122(94)205)135(218)160-85(39-72-21-15-13-16-22-72)126(209)158-82(37-64(2)3)118(201)149-54-108(194)175-114(69(9)181)140(223)172-99(136(219)161-87(42-75-29-33-78(185)34-30-75)130(213)177-116(71(11)183)138(221)153-67(7)117(200)146-50-106(192)157-96)63-230-229-61-97(170-125(208)83(38-65(4)5)155-104(190)52-148-120(203)88(43-76-47-144-80-26-20-19-25-79(76)80)162-128(211)90(45-101(143)187)156-105(191)53-152-123(95)206)134(217)159-84(41-74-27-31-77(184)32-28-74)119(202)150-55-109(195)174-113(68(8)180)139(222)165-89(44-100(142)186)121(204)147-48-102(188)145-49-107(193)173-115(70(10)182)141(224)176-112/h13-34,47,64-71,81-99,112-116,144,178-185H,12,35-46,48-63H2,1-11H3,(H2,142,186)(H2,143,187)(H,145,188)(H,146,200)(H,147,204)(H,148,203)(H,149,201)(H,150,202)(H,151,205)(H,152,206)(H,153,221)(H,154,189)(H,155,190)(H,156,191)(H,157,192)(H,158,209)(H,159,217)(H,160,218)(H,161,219)(H,162,211)(H,163,210)(H,164,220)(H,165,222)(H,166,207)(H,167,216)(H,168,212)(H,169,214)(H,170,208)(H,171,215)(H,172,223)(H,173,193)(H,174,195)(H,175,194)(H,176,224)(H,177,213)(H,196,197)(H,198,199)/t66-,67-,68+,69+,70+,71+,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,112-,113-,114-,115-,116-/m0/s1 InChIKey Standard 1 1.0.6 InChI iupac.org 2021.05.07 OIRWBFAFBZPLGW-ADEHTVSPSA-N Log P XLogP3-AA 7 3.0 sioc-ccbg.ac.cn 2021.05.07 -6.8 Mass Exact 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3336.2254893 Molecular Formula 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 C141H194N36O47S6 Molecular Weight 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3337.7 SMILES Canonical 1 2.3.0 OEChem OpenEye Scientific Software 2021.05.07 CCC(C)C1C(=O)NC(C(=O)NC(C(=O)NC2CSSCC3C(=O)NC(C(=O)NC4CSSCC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(CSSCC(C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NCC(=O)NCC(=O)NC(C(=O)N1)C(C)O)CC(=O)N)C(C)O)CC5=CC=C(C=C5)O)NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)CNC4=O)CC(=O)N)CC6=CNC7=CC=CC=C76)CC(C)C)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N3)C)C(C)O)CC8=CC=C(C=C8)O)C(C)O)CC(C)C)CC9=CC=CC=C9)NC(=O)C(NC(=O)C(NC(=O)CNC2=O)CCC(=O)O)CO)CO)CC(=O)O)CC1=CC=CC=C1 SMILES Isomeric 1 2.3.0 OEChem OpenEye Scientific Software 2021.05.07 CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H]4CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H](C(=O)N1)[C@@H](C)O)CC(=O)N)[C@@H](C)O)CC5=CC=C(C=C5)O)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC4=O)CC(=O)N)CC6=CNC7=CC=CC=C76)CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N3)C)[C@@H](C)O)CC8=CC=C(C=C8)O)[C@@H](C)O)CC(C)C)CC9=CC=CC=C9)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC2=O)CCC(=O)O)CO)CO)CC(=O)O)CC1=CC=CC=C1 Topological Polar Surface Area 7 E_TPSA 3.4.8.18 Cactvs Xemistry GmbH 2021.05.07 1450 Weight MonoIsotopic 1 2.1 PubChem ncbi.nlm.nih.gov 2021.05.07 3335.2221345 230 30 30 0 0 0 0 0 1 -1