2477
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
8
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
3
3
4
4
4
5
5
5
6
6
7
7
8
8
8
8
9
9
9
10
10
10
11
11
11
12
12
13
13
13
14
14
14
17
17
17
18
18
18
19
19
19
20
20
21
21
21
22
22
22
23
23
24
24
26
26
27
27
28
15
16
15
16
17
20
21
22
23
24
25
25
26
25
27
9
10
13
14
11
29
30
12
31
32
12
33
34
35
36
15
37
38
16
39
40
18
41
42
19
43
44
20
45
46
47
48
23
49
50
24
51
52
53
54
55
56
28
57
28
58
59
2
2
1
1
1
1
1
1
1
1
1
2
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
3.4964
3.8622
3.6732
-2.524
-5.2619
-6.9627
-7.4998
6.4504
6.7803
7.8567
7.9245
8.6094
5.5741
5.7519
4.1607
4.3531
2.314
1.2706
-0.1567
-1.1698
-2.8788
-3.4936
-4.2731
-4.9078
-6.6189
-8.279
-8.7995
-9.2519
5.9316
7.1291
8.3629
7.8476
7.5384
8.6197
9.6714
8.545
5.9972
5.502
5.6737
6.3244
2.241
2.1059
1.3403
1.4927
-0.321
-0.2253
-1.0876
-0.9249
-2.214
-2.8391
-3.4798
-3.2332
-4.5135
-4.2754
-4.9788
-5.5874
-8.5385
-9.4905
-10.3009
1.8204
-2.1009
-0.0817
-0.9008
-0.0902
1.3323
-0.5443
-0.1
0.7141
-0.3369
1.6391
0.969
0.6685
-1.419
0.8783
-1.2335
0.1131
-0.5535
-0.3711
-1.0788
0.5231
-1.6359
0.7275
-1.504
0.2437
1.6249
-0.1941
0.8906
1.2811
0.0503
-1.1453
-0.6114
2.6214
1.7993
0.7858
1.6168
1.6548
0.1251
-2.0346
-1.9951
-0.2911
1.1874
-0.1458
-1.6249
0.7089
-0.7597
-0.7013
-2.1481
1.104
0.9624
-1.2708
-2.7011
1.7947
0.464
-2.0201
-2.0114
2.4952
-0.831
1.1483
1.1085
-1.397
-0.2355
0.0122
0.0867
-0.7254
0.6878
0.1742
-1.089
0.7495
-0.6797
0.51
1.1659
-0.1298
0.6699
-0.6705
-0.7289
0.1618
-0.3646
0.5348
-0.0248
0.8339
-0.6226
0.2639
0.0143
-0.7741
0.5957
-0.1274
-1.484
-1.8906
0.2062
1.8096
-0.384
-1.5102
0.3175
1.3918
1.389
2.1167
0.7751
-0.8672
-1.7458
-0.8008
1.1781
0.244
-0.4072
-1.3882
1.5626
0.5605
-0.6684
0.981
1.8699
0.8595
-0.5413
-1.688
-0.7022
0.9585
-1.3671
1.1375
-0.1838
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
000009AD00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
68.3078
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
45.681
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10 15 18040715874802552249
10162869 55 17774994713590122549
10299344 5 13984663650735087123
10904742 90 17530963579514810819
11135609 127 18337953519398714420
11135926 11 15574708115194584107
11315181 36 18131636686659444123
11607047 141 17676475118331914256
12089408 11 17240483623667489059
12664476 115 18410849971245042153
12838862 33 17632285788412876730
13673619 4 7853574599843628671
14118638 360 17274831203120217954
14123256 10 12463571781426840861
14150022 121 18260827047818381213
14251764 18 18334574659128921198
14251764 46 18410573989446418432
14933364 13 18410575101848222857
15183329 4 18060140929107470971
15419008 47 18409161100258471789
15461852 350 18130786806730657823
15510794 2 18410298007738927166
15840311 113 17095246939170877908
1754911 235 15626223515930724769
1818759 1 12607402209203059309
19315958 150 18411142424316449670
20157964 124 17846500313883337846
21033648 29 18339911731984023312
21150785 3 14333407852871808403
21267235 1 8574713503029329078
22224240 67 15502375634005201329
232437 2 18113337505130769514
23576562 1 16486394625151491761
246663 6 10953458522483524019
249057 3 17346595304957866829
4073 2 18187369856491595218
4325135 7 14692573216898727169
4339292 15 17988637567722591895
44280117 145 18341612664558390879
504579 68 15770057233018797607
5385378 56 17241039916606751467
5758199 1 16950280711076477579
59682541 35 17312825991802651513
636775 72 18336827482322190381
67123 10 18334576850205852615
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
539.58
33.69
1.65
1.01
26.12
0.1
-0.02
-11.37
1.03
-0.13
-0.16
-1.01
-0.02
1.53
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1131.185
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
303.2
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
76
84
38
17
52
22
44
35
42
71
98
3
79
99
33
34
7
74
32
56
18
14
64
82
104
59
11
41
66
67
25
102
73
21
92
89
68
6
75
55
63
94
87
29
10
46
101
31
47
54
57
62
16
88
12
105
19
5
103
15
93
97
96
50
91
9
83
65
40
100
4
72
13
28
48
27
61
26
23
20
39
86
51
49
77
70
85
43
36
78
24
69
30
81
60
58
90
45
37
2
53
95
8
80
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
24
1 -0.57
13 0.06
14 0.06
15 0.57
16 0.57
17 0.3
2 -0.57
20 0.27
21 0.27
22 0.27
23 0.37
24 0.37
25 0.72
26 0.16
27 0.16
28 -0.15
3 -0.42
4 -0.81
5 -0.84
57 0.15
58 0.15
59 0.15
6 -0.62
7 -0.62
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
8.6
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
9
1 1 acceptor
1 2 acceptor
1 4 cation
1 7 acceptor
4 5 6 7 25 cation
5 8 9 10 11 12 rings
6 3 8 13 14 15 16 rings
6 4 5 21 22 23 24 rings
6 6 7 25 26 27 28 rings
28
0
0
0
0
0
0
0
1
1