2473338 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 16 16 8 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 5 5 5 6 6 7 7 8 8 9 9 9 10 10 10 13 14 14 15 15 16 16 17 18 18 19 19 20 22 22 23 24 24 24 25 12 17 21 23 14 24 11 9 11 12 12 13 17 25 21 25 14 26 27 11 13 15 16 28 29 19 30 20 31 18 21 22 20 32 33 23 34 35 36 37 38 39 1 1 1 1 1 1 2 1 1 1 2 1 2 1 1 2 1 1 1 1 1 2 2 1 1 1 1 1 1 1 2 1 2 1 1 2 1 1 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 1.07 5.7311 -1.9869 -3.8085 -1.5506 -0.6032 1.5083 3.5967 -1.3991 -2.9489 -2.824 -0.506 -1.8311 -0.9818 -4.1643 -1.9442 2.0755 3.413 -4.2625 -3.1535 4.1035 4.2652 5.546 -1.6435 2.2986 -2.3634 -0.6859 -0.8574 -0.0313 -5.0404 -1.0871 -5.2035 -3.2297 3.9637 6.381 -1.5364 -0.7175 -2.449 1.8257 -0.5738 0.8442 -3.2175 -1.3252 -0.9912 1.1848 -0.2727 0.3676 -2.3936 0.8232 -0.596 -0.0621 1.6523 -3.264 1.3235 2.996 -0.2025 0.1508 2.664 3.4999 0.42 0.3041 0.677 -4.0237 0.0148 -2.7502 -2.4934 -4.2978 -2.9181 0.688 3.6604 3.0564 4.5442 0.151 0.8587 -5.0707 -3.6659 -3.9519 -0.0466 1.6671 -0.501 -0.7975 0.4456 0.9799 0.7358 -0.9701 -2.023 1.3783 0.1393 0.5331 1.0737 0.2529 0.2069 -0.3419 -0.1226 0.2461 0.3989 -0.7125 -0.6034 -0.7756 1.5375 1.1914 -1.9161 -2.0229 1.7601 2.2004 0.549 -0.2142 -0.4357 -0.0418 -1.0867 -0.892 2.5662 1.8532 -1.6165 -2.3766 -2.6519 -2.9968 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 0025BD7A00000002 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 60.9993 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 40.709 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10411042 1 17830177161942468075 11370993 70 18339079259525986590 11582403 64 16264825340767403643 11640471 11 17603877671525078352 12107183 9 17752753642423657064 12160290 23 18268169680197612243 12173636 292 18335698278735430493 12236239 1 17385723582263875032 12788726 201 17606705739722201603 13583140 156 18059850693341890682 13911987 19 16916785253805727512 14294032 229 18410014330250316441 14739800 52 18043253651357965356 15463212 79 18334849519856216962 16752209 62 18335135401822677779 16988056 13 16173397332735421661 17357779 13 17272558688743042159 173720 79 17895191074070392385 17818456 19 18116143377685655288 1813 80 17766007477085715643 20511986 3 17603855715863634540 21033650 10 18117020865342590112 21304303 282 18193247802671909527 2132832 1 17898566733728947260 23557571 272 18342464767819013328 23559900 14 18340494344603647958 23598288 3 17895772788535561131 26353 1 17765989889415788775 341906 21 18334579032039215644 4015057 19 16917345944268156394 474 4 16805610226652911752 57527293 21 17843409733153763490 7064713 232 17968374537934976796 9981440 41 18187929422242136163 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 490.52 10.22 3.92 1.69 11.39 2.58 0.46 -6.43 0.67 -6.63 1.56 1.27 0.78 0.17 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 1052.348 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 272.7 Conformer RMSD 7 2009.12.11 0.8 Diverse Conformer ID List 6 2012.02.08 2 29 16 58 33 34 54 43 35 25 63 66 52 62 53 36 49 60 55 37 64 50 41 40 45 32 21 51 15 56 44 17 59 39 23 47 5 57 61 10 42 24 20 19 11 65 28 26 48 27 31 14 1 13 46 8 6 30 9 7 3 38 22 12 4 18 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 31 1 -0.24 10 0.09 11 0.54 12 0.65 13 0.18 14 0.28 15 -0.15 16 -0.15 17 0.41 19 -0.15 2 -0.08 20 -0.15 21 0.3 22 -0.15 23 -0.11 24 0.28 25 0.47 3 -0.56 30 0.15 31 0.15 32 0.15 33 0.15 34 0.15 35 0.15 39 0.15 4 -0.57 5 -0.42 6 -0.63 7 -0.62 8 -0.57 9 0.3 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 5 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 8 1 3 acceptor 1 4 acceptor 1 7 acceptor 3 7 8 25 cation 5 2 18 21 22 23 rings 6 10 13 15 16 19 20 rings 6 5 6 10 11 12 13 rings 6 7 8 17 18 21 25 rings 25 0 0 0 0 0 0 0 1 1