2403
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
8
8
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
3
3
4
4
4
5
5
5
6
6
6
7
7
7
8
8
9
9
10
11
11
12
13
13
14
14
14
15
15
16
17
17
17
19
21
21
22
22
23
23
24
24
25
25
26
27
27
28
28
28
29
29
30
18
20
10
12
14
16
19
28
18
20
39
24
51
52
8
9
12
11
18
10
21
22
13
20
31
15
19
17
32
33
16
23
27
24
34
35
36
25
37
26
38
29
40
41
42
26
43
44
30
45
46
47
48
30
49
50
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
1
1
2
2
1
1
1
1
2
1
1
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
2
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
0.1021
-3.8421
2.827
-2.1977
-2.0455
5.2099
0.7817
-0.492
1.2924
2.5752
-1.6543
1.7508
-1.9445
4.0468
-2.3778
-2.5292
3.9878
-0.7308
-1.843
-2.6768
0.7824
3.3766
-2.6566
5.2904
1.5727
2.8496
-2.947
-2.2148
-3.0755
-3.2178
1.7619
4.198
4.8853
3.7948
3.1443
-1.548
-0.2104
4.3701
-2.4976
-2.5522
6.1289
5.4903
1.1843
3.4457
-3.0598
-3.2328
-1.9059
-1.5187
-3.2921
-3.5445
6.0652
4.4502
4.123
1.8779
0.4443
-2.3981
3.337
-3.6556
1.3092
1.8031
1.2183
0.6733
1.1451
0.8248
-0.2452
-0.1149
-0.9141
-2.2634
-1.6391
3.2343
-1.1839
2.1302
1.5496
0.442
-0.4999
-2.2035
1.3236
0.7783
-3.2231
-3.6356
-1.4487
-2.7889
0.7183
0.3263
0.2129
-2.0675
-1.9342
-1.0876
1.9765
0.0144
4.2032
0.541
-1.9378
-1.7798
1.5769
0.6102
-4.2679
-4.0331
-3.4451
-4.3339
-1.1348
-3.5088
-4.0116
-3.9131
-1.0123
-1.6104
-0.4267
-1.23
-1.4175
-1.7328
-0.3316
-0.7541
0.9956
0.9072
-0.9188
-1.1826
-0.7529
-0.9686
0.426
0.0994
-1.065
-1.0712
-1.7536
-1.3547
2.2666
2.0308
1.7436
-1.6279
3.3995
3.2811
1.0284
-1.9799
2.6834
2.3291
-2.2599
-1.9613
-0.3446
-0.0729
-1.7028
-2.7907
2.3766
1.9506
-1.6873
2.0362
-0.9754
-2.6182
4.3823
4.1744
0.759
-1.9661
-3.0109
-1.5083
3.7011
3.0751
-2.1575
-2.3615
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000096300000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
55.2091
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
61.081
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
107951 10 17680439853043372135
11578080 2 18059288889449009545
12156800 1 15511169390781757617
12160290 23 18116412796367756925
12363563 72 17683209789053023395
12549972 3 18059282180767563392
12553582 1 17969775470298527315
12633257 1 16557651727094675827
12788726 201 17821720650825437673
13583140 156 16486414441824257689
14022347 108 18114450228283708757
14114206 34 17385718118917469655
17909252 39 18044964448220816316
17974551 9 16558205906999581258
19309040 13 13624093006988895878
19315092 285 16556473140834829630
20600515 1 15437845352416724129
20642791 239 15527436398715527220
21133410 230 17469646960182171675
23559900 14 18270386210462653140
25265897 201 17483070965843316458
3383291 50 18056468448718471143
35225 105 17604422995190932709
484985 159 17769116561225244166
70634741 139 18267603325517170198
7097593 13 17059225910708781770
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
585.72
7.97
4.63
3.27
7.21
0.74
-2.95
8.01
0.92
-1.06
3
0.43
0.01
4.19
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1315.463
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
313.8
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
51
40
8
7
27
41
53
25
20
31
52
19
28
29
39
5
6
43
24
47
35
44
30
11
48
18
15
34
12
49
23
46
4
22
9
21
36
45
2
10
50
16
37
13
26
14
17
3
42
38
32
33
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
40
1 -0.57
10 -0.15
11 0.06
12 -0.3
13 -0.05
14 0.26
16 -0.15
18 0.62
19 -0.3
2 -0.57
20 0.62
21 -0.15
22 -0.15
23 -0.15
24 0.27
25 -0.15
26 -0.15
27 -0.15
28 0.26
29 -0.15
3 0.05
30 -0.15
31 0.15
36 0.15
37 0.15
38 0.15
39 0.37
4 0.05
40 0.15
43 0.15
44 0.15
45 0.15
49 0.15
5 -0.49
50 0.15
51 0.36
52 0.36
6 -0.99
7 -0.05
8 0.06
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
5.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
12
1 1 acceptor
1 2 acceptor
1 3 cation
1 4 cation
1 5 donor
1 6 cation
1 6 donor
5 3 7 9 10 12 rings
5 4 13 15 16 19 rings
5 5 8 11 18 20 rings
6 15 16 23 27 29 30 rings
6 9 10 21 22 25 26 rings
30
0
0
0
0
0
0
0
1
3