238455
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
3
3
4
4
4
4
5
5
5
6
6
7
8
9
9
9
10
10
10
11
11
12
12
12
13
13
13
14
14
14
15
15
16
16
17
7
6
12
13
8
16
5
7
8
18
6
19
20
21
22
9
11
10
23
24
14
25
26
15
27
28
29
30
31
32
33
34
35
36
17
37
17
38
39
2
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
4
5
7
8
18
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
1.2403
-3.6829
0.3345
0.1039
-1.2383
-2.446
1.2708
0.3141
2.4567
3.7725
0.4655
-3.7144
-4.8457
4.1038
0.6564
0.5223
0.6866
0.0919
-1.3256
-1.1984
-2.3769
-2.4414
2.5345
2.2515
3.7266
4.5779
0.4405
-3.0338
-3.4888
-4.7081
-5.7747
-4.8751
-4.8417
5.0876
3.3793
4.1352
0.7816
0.538
0.8341
2.0445
1.0195
-1.097
0.6635
1.2233
0.4361
1.5107
-0.7993
1.6752
1.8755
-1.6952
0.9654
0.3287
0.6781
-3.0288
-2.4026
-3.3975
0.7947
2.2787
1.2036
-0.6212
0.4795
0.7867
2.5356
2.7777
2.0244
-1.3979
1.6931
-0.0342
1.247
0.803
-0.7292
0.3913
0.8144
0.5435
-0.2439
-3.7793
-2.638
-4.431
1.0368
-0.0833
1.0526
-0.594
-0.0754
-0.5917
-0.0722
-0.2552
-1.0143
-0.2675
-1.286
1.379
-0.6426
0.6082
-0.9418
1.3489
0.3986
-1.6851
-0.3666
1.0194
-0.3081
-1.6882
-1.6505
-1.66
0.3533
-0.9957
-2.328
1.8309
1.7679
1.7491
-0.3071
-0.3573
-1.7366
1.0689
1.4164
0.0184
-1.7165
2.4079
0.6902
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0003A37700000018
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
32.986
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
25.372
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10922049 32 18409169951831659980
12532896 13 18267297827716922148
12592029 89 18333727996710829648
12715332 25 18411411843672738472
12788726 201 17689428712866951586
13083527 12 18118101603214576291
14178342 30 18263664973217609537
14251751 93 18200029689318730375
15309172 13 18335704987289990253
15502708 68 18408884010062672148
15906896 17 18047474718617806574
16945 1 18263086521956849694
18915476 22 18117256091932051741
19784866 9 18341051822162657505
20197701 30 18338226158819977720
204376 136 18335424616151373869
20567600 347 18409169926257216983
20600515 1 17117183006738728184
20645476 183 18043261342952744244
20645477 70 18337103455181018133
20711985 344 17689709088347592386
21054139 6 18198609107837730871
21421861 104 18122635950560733825
21524375 3 18339640139363212989
23419403 2 17688081574673066418
23558518 356 17836071652115208037
23728640 28 18266450096242260018
298252 57 17489308628429660900
3060560 45 18334851753297558093
3250762 1 17407954852642421800
366044 4 18340485659673711084
474229 33 18263930011000829315
6138700 20 18266181630890482438
633830 44 18201453479335505197
7364860 26 18268429040582569479
81228 2 17543615891437731921
81539 233 18334292050439197493
9999458 23 16588022424661091168
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
334.02
6.55
3.49
1.26
5.15
3.6
0.16
-5.48
0.24
-2.21
0.13
0.13
0.32
-0.29
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
664.484
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
198.5
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
24
279
251
220
277
107
168
191
211
19
196
204
66
239
124
60
106
208
247
201
238
221
22
274
268
259
59
134
232
234
166
148
190
126
185
104
81
245
177
269
110
237
109
87
280
10
260
246
189
178
122
162
79
71
195
243
101
186
281
73
233
69
163
145
194
4
286
223
216
180
127
271
138
213
235
176
250
212
37
254
170
165
272
146
89
207
53
91
135
202
276
139
264
68
83
6
85
192
197
115
120
1
114
121
227
151
267
217
261
117
125
152
210
198
142
175
164
26
206
278
282
113
23
12
161
171
128
222
96
248
188
5
262
63
156
2
141
133
27
200
111
130
52
92
32
9
256
78
228
118
283
181
240
16
72
57
184
209
158
129
173
159
187
18
199
88
74
253
172
86
97
39
56
154
255
13
252
182
49
205
77
242
225
214
93
263
215
265
102
31
112
131
241
132
38
140
167
147
174
34
179
47
67
65
84
8
183
64
155
95
70
123
224
119
21
136
76
80
275
98
42
55
266
150
100
231
90
144
160
99
218
45
249
219
17
137
48
153
44
143
40
30
270
108
226
51
244
157
35
82
193
36
203
169
105
46
103
11
94
116
3
50
273
258
20
257
58
14
229
75
149
285
54
28
236
7
43
284
230
15
29
41
61
25
33
62
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
18
1 -0.57
11 -0.15
12 0.27
13 0.27
15 -0.15
16 0.16
17 -0.15
2 -0.81
27 0.15
3 -0.62
37 0.15
38 0.15
39 0.15
4 0.2
6 0.27
7 0.45
8 0.17
9 0.06
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
7
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
5
1 1 acceptor
1 14 hydrophobe
1 2 cation
1 3 acceptor
6 3 8 11 15 16 17 rings
17
1
0
1
0
0
0
0
1
5