22432
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
3
3
3
4
4
4
5
5
5
6
6
6
7
7
8
8
9
9
10
10
11
11
12
12
13
13
14
14
16
16
17
17
4
24
25
15
34
35
18
36
37
5
7
19
6
20
21
8
22
23
9
10
11
12
13
26
14
27
16
28
17
29
15
30
15
31
18
32
18
33
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
2
1
1
1
2
1
1
1
2
1
2
1
1
1
2
1
1
1
4
1
5
7
19
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
1.7119
5.277
-6.1964
1.3019
-0.1168
-0.7669
2.3619
-2.2049
3.0424
2.6195
-3.2167
-2.4929
4.0165
3.5935
4.2921
-4.5475
-3.8236
-4.8509
1.2312
-0.1143
-0.7683
-0.1767
-0.7011
1.7459
2.6499
2.8362
2.0868
-2.9905
-1.6995
4.5538
3.7992
-5.3391
-4.0471
5.4778
5.7841
-6.4169
-6.9416
2.8702
-2.2391
-0.9903
1.8271
1.3253
0.4172
0.744
0.044
0.5385
-0.0108
0.8512
-1.1001
-0.4581
-1.0076
-1.2314
0.5064
-1.4449
-0.6416
2.3188
0.8052
2.2004
-0.5028
0.9071
2.4956
3.1994
1.1331
0.1487
1.7484
-1.7304
-0.6229
-1.6034
1.1408
-2.3416
-2.7994
-2.4013
-1.822
-0.408
-1.0265
0.1647
-0.3413
-0.0739
-0.4356
0.6238
-0.0105
0.3689
1.1748
-1.1395
0.8668
-0.3604
1.2334
-1.081
0.1055
0.6301
-0.5972
-0.1021
0.9048
-1.4024
-0.5715
0.7271
1.6048
-1.9732
-0.8022
2.0597
-2.0719
1.4357
-0.7521
2.1639
-1.9667
1.0207
-1.1695
-0.6528
1.0245
-0.8727
0.0171
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
000057A000000002
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
63.8935
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
40.597
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
12107183 9 18197507216402882081
12363563 72 18333455318022300136
12553582 1 18040714736477970088
12555020 224 18335414686778017567
12892183 10 16271648863138206634
13167823 11 18413107290444533107
13533116 47 18270960253973273201
13583140 156 16486681472789404985
13675066 3 17846498140782593673
1420 369 18343303669199565387
14341114 328 15195278759465722202
14366163 111 12468356851350839492
14528608 73 10809343360599510739
15183329 4 18187357698092573797
15188451 53 17846489336321332599
15210252 30 8502365646791632958
15848700 24 18334575724729352712
15885798 251 18410575067520633233
16752209 62 17531518793905083809
17349148 13 18060424629404748317
17492 89 18194123138624458859
1813 80 18259705584031739652
18186145 218 17240482554563556313
18222031 100 18407759222837143856
20369508 70 17967808379566846568
20388580 30 18333735719357732076
204376 136 12175618477652229997
20645477 70 18187082909535943329
21618674 25 11383833779075325941
21652331 79 8502382126527834455
21728266 224 17417800808066121487
21756936 100 15408612693515786920
221357 26 13623524645413201422
22224240 67 18058435660542140016
2255824 54 18188495799447843484
22646028 1 18413390942895796809
22646028 28 18412263951724389015
22854114 59 11527951153336728721
23253445 4 16917340459373412146
23557571 272 15338575885136650633
23559900 14 17274838955578683964
23590187 198 18342738516376268811
2637199 183 10881396513430478872
26918003 58 17489585628060900882
270888 7 9511159855930934090
29717793 49 18411414038617350277
3004659 81 18342746238321343693
312423 11 18261688046652254617
32948 21 17240473694188475717
351380 3 18334294232451739594
42 15 17989489610583964417
465052 167 18408611378587420687
5104073 3 18059865003877457483
5207 123 18409728430782096693
5374978 207 16630529548343233251
543368 44 10809349940605816319
559249 180 18340767040567193083
573450 72 18060140946941513097
5924683 9 16702007730356366295
633830 44 17531242911571728905
6442390 28 10087630533550311788
67856867 119 18199183082302846089
76465 3 18410011013812909700
7808743 9 9654990266141810014
7970288 3 18262234426558941066
8988823 20 17131824417507700289
960060 61 17603309271073282422
9709674 26 18264491874201190779
9841814 1 17894903062354385200
9971528 1 18408882953754191288
9981440 41 17257364675145731625
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
355.49
12.42
2.01
1.1
7.6
0.54
-0.02
-7.19
-0.86
-1.51
0.51
-0.79
0.13
-0.78
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
750.496
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
200.5
Conformer
RMSD
7
2009.12.11
0.6
Diverse Conformer
ID List
6
2012.02.08
2
19
11
21
30
22
16
13
9
5
1
17
12
27
29
4
26
6
7
23
3
8
24
25
14
18
15
20
28
10
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
31
1 -0.99
10 -0.15
11 -0.15
12 -0.15
13 -0.15
14 -0.15
15 0.1
16 -0.15
17 -0.15
18 0.1
2 -0.9
24 0.36
25 0.36
26 0.15
27 0.15
28 0.15
29 0.15
3 -0.9
30 0.15
31 0.15
32 0.15
33 0.15
34 0.4
35 0.4
36 0.4
37 0.4
4 0.41
6 0.14
7 -0.14
8 -0.14
9 -0.15
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
8
1 1 cation
1 1 donor
1 2 cation
1 2 donor
1 3 cation
1 3 donor
6 7 9 10 13 14 15 rings
6 8 11 12 16 17 18 rings
18
1
0
1
0
0
0
0
1
1