221151
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
4
5
5
5
6
6
6
7
8
8
9
9
10
10
11
11
12
12
13
14
14
14
15
15
15
17
18
18
18
7
17
16
34
16
17
6
7
8
9
19
20
12
10
21
11
22
13
16
14
15
13
23
24
25
26
27
28
29
30
18
31
32
33
1
1
1
1
2
2
1
2
1
1
1
1
1
2
1
2
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
-1.0125
4.8673
4.0204
-1.5667
0.2667
-0.9348
0.1634
1.4661
-1.7418
2.5867
-3.0696
1.2841
2.4959
-3.8182
-3.9322
3.8501
-1.8304
-3.0946
-0.5931
-1.5303
1.5274
-1.174
1.2204
3.3458
-3.1517
-4.2999
-4.5872
-3.3776
-4.5195
-4.6296
-3.6281
-3.7367
-2.8576
5.7004
-1.7855
-0.0132
2.0373
-1.5215
0.2379
1.0544
-1.1398
0.8913
1.511
0.1502
1.7276
-1.8807
-1.2357
2.1859
1.5226
0.8226
-1.9221
-2.6423
1.9414
0.4759
1.972
1.707
-2.961
-1.847
2.3044
3.1511
1.4555
1.4688
0.605
2.3611
-2.0826
-2.7169
-3.6504
0.4776
-0.7662
0.5843
0.1383
1.4928
-0.6512
-1.0571
-0.5279
-0.4077
0.1256
-0.0325
0.1874
-0.1529
0.095
1.4067
-1.0297
0.2261
0.3667
0.0024
-1.6066
-1.7709
-0.5077
1.0353
-0.0524
0.3849
2.2674
1.2209
1.6779
-1.9692
-0.922
-1.1385
-0.7698
0.8846
-0.3461
0.7496
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00035FDF00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
46.7529
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.507
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11132069 177 18261393321247378605
11680986 33 18339088073015461102
122479 349 18342176643979655716
12251169 10 18259988145619293244
12390115 104 18269006434949422148
12633257 1 18189041041456637240
13140716 1 18409720743376199154
13296909 8 18338236067319981743
13380535 21 18409735028184296110
13380535 76 18411132498435388918
13583140 156 16732977596470740309
13764800 53 18343021099032535728
14787075 74 18272926112340003097
15295992 7 17774707723960020960
16945 1 18120929503966029414
1741750 31 18272090474216347264
18186145 218 18126850391372326621
204376 136 18337955597561109005
20510252 161 18269274732369850154
21501502 16 18409161100046799426
21524375 3 18271797978406491132
22182937 141 18343588442711341609
23402539 116 18340482391683919687
23419403 2 15407769397634733743
23559900 14 18270680866688616174
2748010 2 18338813237868299222
350125 39 18194122056261006380
4340502 62 18339933598053404241
474 4 18271243794613468969
5104073 3 18336812179242101184
57003041 12 18333731346948759826
633830 44 17843406185310550845
69090 78 18334856065739673729
81228 2 18187654655946474675
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
346.95
7.65
2.9
1.04
3.57
1.12
-0.13
-4.31
-1.54
-2.38
-0.35
-0.82
-0.18
-0.04
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
717.164
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
197.4
Conformer
RMSD
7
2009.12.11
0.6
Diverse Conformer
ID List
6
2012.02.08
1
141
184
11
176
170
133
173
32
163
24
20
15
117
76
160
166
174
9
150
167
192
42
164
134
37
142
18
52
185
180
75
118
130
113
155
132
105
95
96
13
188
74
169
177
138
31
112
195
168
46
187
103
30
107
143
12
165
116
62
47
85
72
136
186
152
63
149
140
154
129
64
44
120
39
108
7
45
137
131
17
86
162
159
127
84
172
27
60
146
59
68
194
73
50
14
125
100
161
189
190
104
41
69
91
2
128
70
139
28
124
81
5
58
66
122
147
21
98
175
61
25
179
148
191
56
51
110
94
153
97
71
82
114
171
29
40
102
182
54
88
77
178
87
92
145
19
193
183
115
106
101
55
6
4
158
93
181
144
90
67
121
79
34
123
22
156
8
197
99
151
53
23
80
57
198
10
65
83
48
43
157
126
3
26
135
109
78
36
49
89
196
33
119
35
38
111
16
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
23
1 -0.23
10 0.09
11 -0.28
12 -0.15
13 -0.15
14 0.14
15 0.14
16 0.63
17 0.66
18 0.06
2 -0.65
21 0.15
22 0.15
23 0.15
24 0.15
3 -0.57
34 0.5
4 -0.57
5 -0.14
6 0.28
7 0.08
8 -0.15
9 -0.29
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
5
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
6
1 2 acceptor
1 3 acceptor
1 4 acceptor
3 11 14 15 hydrophobe
3 2 3 16 anion
6 5 7 8 10 12 13 rings
18
0
0
0
0
0
0
0
1
1