220249
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
16
16
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
2
5
8
8
8
9
9
9
10
10
11
12
12
13
13
14
14
15
15
16
16
16
17
17
18
18
19
20
20
21
21
22
22
23
23
24
24
24
25
3
4
8
12
6
7
10
16
11
9
11
26
10
27
28
29
30
13
14
15
20
21
17
31
18
32
33
34
35
19
36
19
37
24
22
38
23
39
25
40
25
41
42
43
44
45
2
2
1
1
2
2
1
1
2
1
1
1
1
1
1
1
1
1
2
1
2
1
1
1
2
1
1
1
1
2
1
1
1
1
1
1
2
1
2
1
1
1
1
1
1
1
8
1
9
11
26
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
-0.1025
4.9913
0.082
0.1714
0.6726
5.2949
5.3121
0.8688
2.3683
3.2772
0.4548
-1.7657
-0.2195
-2.3749
-2.4348
5.7988
-3.6892
-3.7492
-4.3763
0.0783
-1.1144
-0.5525
-1.7452
-5.7818
-1.4643
0.6521
2.5865
2.6345
3.1006
3.0951
-1.8537
-1.9668
5.5103
5.4988
6.8778
-4.1657
-4.2733
0.8066
-1.3458
-0.328
-2.4561
-5.7927
-6.3012
-6.3525
-1.9544
-2.1685
-0.203
-2.588
-3.0764
0.223
-0.5179
-1.1462
-0.7041
-0.9908
0.1957
0.3582
-1.5987
1.6016
-1.6186
-1.1409
1.3331
-1.1682
-0.6906
-0.7043
2.0763
2.2271
3.239
3.3897
-0.2231
3.8956
-0.4156
-1.3594
-1.8174
0.5603
1.0141
-1.9684
-1.1212
1.6371
2.0841
1.1721
-1.1803
-0.3289
1.6166
1.8424
3.638
3.9005
0.8528
-0.7378
-0.4152
4.8016
0.096
-0.2212
1.4702
-0.9995
2.0403
1.165
-1.2796
-0.175
-0.0365
-0.3357
0.8371
-0.0601
0.364
-1.3043
1.0633
-0.6104
-1.4285
0.939
-0.307
-0.8934
1.2022
-1.3362
0.7595
-0.4394
-0.5098
-1.2058
0.9746
-0.708
-1.3526
0.3676
-2.1901
2.0426
-1.6182
0.1226
-0.5618
-2.4052
1.8197
-1.5508
2.1907
-2.3211
1.4024
-0.6406
-1.2548
0.4756
-0.8539
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00035C5900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
49.9573
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
35.56
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
104564 63 18339921502997717449
10670039 82 18336282150107365574
10871710 139 18337679624342383473
10930396 42 17979037739619514304
11578080 2 14690364255421447897
11582403 64 15579476468789498293
11646440 116 18340215167313245075
12035759 4 18187076230946388928
12293681 4 18187374246227116515
12422481 6 18052289252365440625
12788726 201 18408886244036516448
13004483 165 18335975454650396404
13140716 1 18193554700013712682
13911987 19 18187935026884774486
14251751 93 18267586806349418050
14840074 17 18341623632511803694
14910302 57 17703519818066098998
14955137 171 18268158724274038699
15439362 3 18050562147675407085
15849732 13 18131635616948947295
16752209 62 18410849933133324442
17357779 13 18270950302397041245
18769570 83 18260543416276528445
20600515 1 18128273352786798406
21236236 1 18340491067127187868
21285901 2 18202008715680195814
21304303 64 18261116326201268997
21641784 216 18261965054588489756
23175994 123 18261679267643720927
23402539 116 18412261757170466542
23419403 2 17416945348785043336
23558518 356 18117006481122881434
23559900 14 17488458758040095386
23566358 2 17985834722427968710
238 59 16604617031832395429
249057 3 18270672182718671783
283562 15 18410856529611948504
3027735 51 18340492149311389834
3084891 8 18341332184737537719
3178227 256 18262812890519460371
350125 39 18268714905417146870
469060 322 18115037315911226417
5171179 24 17916570055244135505
7164475 11 18337946775951497046
7226269 152 18334288803771086018
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
492.84
9.9
3.92
1.43
10.16
3.63
0.18
-2.65
-2.17
-1.9
-0.52
-0.22
-0.04
-0.42
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1014.071
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
283.3
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
62
75
68
52
101
50
84
95
106
87
48
10
49
85
51
46
69
70
80
2
79
77
67
103
72
100
23
19
18
99
41
83
78
24
21
32
90
29
14
11
42
4
98
5
91
12
105
66
73
89
7
43
86
65
15
74
26
97
71
28
3
54
96
55
38
16
22
17
40
35
60
93
81
6
63
30
36
104
56
53
57
27
8
92
25
109
94
33
31
9
108
102
20
59
88
61
45
13
44
47
82
107
64
58
34
39
76
37
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
33
1 1.2
10 0.11
11 0.42
12 -0.01
13 0.09
14 -0.15
15 -0.15
16 0.11
17 -0.15
18 -0.15
19 -0.14
2 1.09
20 -0.15
21 -0.15
22 -0.15
23 -0.15
24 0.14
25 -0.15
3 -0.65
31 0.15
32 0.15
36 0.15
37 0.15
38 0.15
39 0.15
4 -0.65
40 0.15
41 0.15
45 0.15
5 -0.57
6 -0.65
7 -0.65
8 0.17
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
7
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
7
1 3 acceptor
1 4 acceptor
1 5 acceptor
1 6 acceptor
1 7 acceptor
6 12 14 15 17 18 19 rings
6 13 20 21 22 23 25 rings
25
1
0
1
0
0
0
0
1
2