219721
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
8
8
8
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
5
6
7
8
9
9
9
10
10
11
11
12
13
13
14
14
15
16
17
18
18
18
19
19
19
20
20
20
9
12
12
14
10
15
11
16
13
17
15
16
17
10
13
21
11
22
12
23
24
14
25
26
27
18
19
20
28
29
30
31
32
33
34
35
36
1
1
1
1
1
1
1
1
1
1
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
9
1
10
13
21
3
1
10
3
9
11
22
3
1
11
4
10
12
23
3
1
12
1
2
11
24
3
1
13
5
9
14
25
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
-0.4253
-0.338
0.8094
2.6081
-2.8217
-0.4317
3.5979
-3.433
-0.6462
0.7766
1.4753
0.4322
-1.5555
-0.9798
0.1617
3.6002
-3.4929
0.2787
4.7204
-4.3366
-1.0944
1.2348
1.7989
0.8683
-1.7383
-0.2468
-1.7677
-0.1866
-0.2399
1.3314
4.3556
5.137
5.5099
-5.069
-3.6999
-4.8723
1.5945
2.1992
-1.4311
1.2606
0.7362
-2.6298
-0.7657
-1.0989
0.2072
-0.2928
0.9139
2.0281
0.1733
0.9976
-2.5444
0.3229
0.0944
-3.6659
0.8217
1.0789
-0.2607
-0.5422
0.758
2.9949
-0.8458
0.4116
1.2934
-3.3753
-4.547
-3.9182
1.0009
1.7373
0.0659
1.5302
1.8464
0.5607
0.784
-1.4809
-0.611
0.3851
-0.4196
0.9252
-0.1163
0.8435
0.4662
0.2267
-0.406
-0.2852
-0.7709
-1.9275
-0.1414
0.4423
0.5796
-1.1287
1.3039
1.3312
1.3455
1.1934
-1.4413
-0.0163
-1.1288
-2.4922
-2.6282
-2.0739
-0.7405
-1.2787
2.3184
0.8767
1.3459
0.6573
1.7785
2.1317
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00035A4900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
55.2346
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
30.491
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10863032 1 15410898461249882708
11132069 177 18335137591928853427
11578080 2 17392212723697084549
12403814 3 17822842199550542924
13140716 1 18192704777556915024
13172582 1 18334575792979330989
13583140 156 17024561517921543896
14178342 30 18337968830755846105
14223421 5 18050852121732019601
14787075 74 17702939378457189329
15209289 33 18271803561863735433
15309172 13 18411129238708217816
15502708 68 18340487772586513571
16945 1 18118964938653805477
18915476 22 18124302814514525261
20028762 73 17985549094397952079
20511035 2 17754759430220057457
21330990 113 18336274444018131596
21501502 16 17905041809181249652
22182313 1 18117273644930562269
23184049 59 18408886252151586840
23419403 2 15451627438871133968
23557571 272 17387420034332037677
2748010 2 18119515558235914612
3250762 1 17687461269636489148
4340502 62 18271815605574538971
465052 167 17676781971336784371
568465 68 18339089275653562585
633830 44 17846502504316671572
6992083 37 18191302891071710647
7364860 26 18055923086692549271
81228 2 17831837411572796194
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
364.64
6.34
2.98
1.35
1.49
3.38
0.32
-2.45
-3.74
0.2
0.73
-0.46
-0.31
0.39
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
761.319
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
202.7
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.01.18
1
136
41
122
151
140
106
124
60
26
155
103
94
61
146
147
129
110
104
102
78
42
22
38
105
44
109
59
139
134
157
64
141
131
47
86
37
75
55
62
160
144
130
18
153
21
36
89
137
70
116
13
87
72
45
149
4
12
81
96
135
19
100
101
90
142
154
50
49
150
51
66
143
35
67
126
148
114
29
115
54
128
161
127
88
156
56
85
25
74
159
84
107
27
113
57
132
162
65
99
117
46
73
48
93
68
15
30
97
125
77
43
40
119
82
95
98
23
33
16
92
83
52
7
108
20
28
118
133
32
2
53
80
138
71
9
158
112
123
111
152
91
58
5
8
31
121
79
63
14
39
11
76
34
6
3
17
120
145
24
10
69
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
20
1 -0.56
10 0.28
11 0.28
12 0.56
13 0.28
14 0.28
15 0.66
16 0.66
17 0.66
18 0.06
19 0.06
2 -0.56
20 0.06
3 -0.43
4 -0.43
5 -0.43
6 -0.57
7 -0.57
8 -0.57
9 0.28
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
7.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
6
1 1 acceptor
1 2 acceptor
1 6 acceptor
1 7 acceptor
1 8 acceptor
8 1 2 9 10 11 12 13 14 rings
20
5
0
5
0
0
0
0
1
1