Amsacrine - PubChem

Amsacrine - Compound Summary (CID 2179) Also known as: Amsidine, Amsidyl, m-AMSA, mAMSA, Amsine, 51264-14-3, meta-Amsacrine, AMSA P-D, Acridinylanisidide Molecular Formula: C₂₁H₁₉N₃O₃S Molecular Weight: 393.45886 InChIKey: XCPGHVQEEXUHNC-UHFFFAOYSA-N Aminoacridine derivative that is a potent intercalating antineoplastic agent. It is effective in the treatment of acute leukemias and malignant lymphomas, but has poor activity in the treatment of solid tumors. It is frequently used in combination with other antineoplastic agents in chemotherapy protocols. It produces consistent but acceptable myelosuppression and cardiotoxic effects. From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
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Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Pharmacology Help top of page show all 3 sub-sections (Pharmacological Action, Therapeutic Uses, Drug Warning)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 11 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Mechanism of Action ...)show first sub-section only Safety and Handling Help top of page show all 9 sub-sections (Reactivities and Incompatibilities, Decomposition, Protective Equipment and Clothing ...)show first sub-section only Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Patents Help top of page Biomolecular Interactions and Pathways Help top of page Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 6 sub-sections (Color/Form, Melting Point, Octanol/Water Partition Coefficient, Solubilities, Other Chemical/Physical Properties ...)show first sub-section only

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