21660
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
8
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
6
7
7
7
7
8
8
8
9
9
9
10
10
10
11
11
11
12
12
15
15
15
16
16
16
17
17
18
18
19
19
20
20
13
17
14
18
15
19
16
20
13
14
8
9
13
21
10
14
22
11
23
24
12
25
26
12
27
28
29
30
17
19
31
18
20
32
33
34
35
36
37
38
39
40
1
1
1
1
1
1
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
7
8
9
13
21
3
1
8
7
10
14
22
3
1
15
3
17
19
31
3
1
16
4
18
20
32
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
-2.4531
2.3577
-5.4021
5.6501
-2.5936
1.8555
-0.7585
0.4385
-0.6885
0.8279
-0.3171
0.953
-2.0351
1.6187
-3.999
4.2231
-3.6668
3.5184
-4.6477
5.1186
-0.8072
0.1693
-1.6486
0.049
1.7753
0.0689
-0.1685
-1.1347
1.1604
1.8063
-3.3588
3.7132
-4.4703
-3.5342
4.1739
3.214
-4.801
-4.4622
5.1855
5.2343
0.4402
0.6513
2.4994
2.1273
-1.6974
-0.8373
-1.073
-0.6705
-2.5125
-1.7366
-3.5305
-3.13
-0.8438
-0.3177
2.2188
2.1375
0.7966
1.0837
2.6125
1.7823
-0.429
0.2453
-2.802
-2.5762
-1.4723
-1.7634
-4.5101
-3.6583
-3.8578
-3.1625
2.9321
3.0907
0.1294
0.6744
0.2215
1.497
1.8553
3.6081
0.7472
2.5043
-0.0366
0.0164
0.2558
-0.052
0.8282
-1.6772
-0.605
0.2686
-1.1234
1.2983
-0.0486
0.6895
0.1525
-0.5951
0.3374
0.0827
0.6327
-0.7004
-0.9578
1.2339
-1.4953
0.8148
-1.5693
-1.9323
1.7835
2.0903
-0.5181
0.6684
1.4824
0.0017
0.8376
0.0939
0.2974
1.7138
-0.8742
-1.6687
-1.7157
-1.3392
1.5427
2.0318
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000549C00000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
28.1031
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
25.374
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11135609 201 18202007629480757553
12107183 9 18335126576271611248
12293681 160 17831831896988321295
12293681 25 11886799918571639452
12390115 104 18340220664243915408
12769317 202 18272927202570989920
12788726 201 17611766882092135062
12930653 34 18260555549607067523
13103583 49 12613034938252446901
13134695 92 17543906807201361687
13140716 1 18261954050761074442
13955234 65 18049169873869915051
13965767 371 17967809397226143500
14123255 52 18410576175748477801
14142880 1 18261385710976592063
14178000 22 18411138077682490598
14178342 30 17822583788690753555
14251764 38 17910945074448183592
14251764 75 18341624685075139233
15061688 2 18413390934036823876
15534591 1 18340768242509462326
16120349 189 18333725827673945397
17834072 32 18412826901768020280
17980427 26 18339633448173873374
19784866 34 18412544280245830393
20238998 120 17474104302911550306
20645477 56 18057898024477114306
212916 134 18340194297977496072
21304253 13 17832135031542848674
21304303 282 18198601401886212582
21401589 2 18271534185862860049
23402539 116 17980194515340209758
23559900 14 18123751950620888115
2838139 119 18272925042418659108
3459 39 18268973397644211560
394222 165 18337106752872305347
5104073 3 18187654548819992153
56616090 46 18411426120344412830
6327066 14 18409443691725992181
67856867 119 18193552277646505955
77188 2 17329146871258474883
7808743 9 18411417353651887153
9981440 41 18335421279220118459
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
376.37
10.23
4.19
1.15
1.91
1.59
0.09
-16.08
-1.12
-1.1
-0.16
0.35
0.24
0.46
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
766.69
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
216
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
100
67
49
119
71
107
3
129
22
53
79
78
44
8
23
18
10
30
85
103
38
72
73
84
115
43
110
106
2
7
6
55
108
96
41
62
69
12
17
51
118
81
98
15
124
36
75
54
21
121
5
57
113
68
91
70
61
42
16
86
92
83
101
76
28
131
29
89
97
19
65
58
48
63
126
32
64
114
74
4
82
56
117
123
11
128
45
99
33
59
77
27
116
111
90
60
9
94
47
93
104
14
122
25
26
109
40
105
39
112
87
95
24
50
52
127
80
120
31
102
20
130
66
125
34
37
13
46
35
88
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
22
1 -0.43
13 0.66
14 0.66
15 -0.05
16 -0.05
17 0.38
18 0.38
19 -0.05
2 -0.43
20 -0.05
3 -0.3
31 0.1
32 0.1
37 0.1
38 0.1
39 0.1
4 -0.3
40 0.1
5 -0.57
6 -0.57
7 0.06
8 0.06
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
10.4
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
5
1 3 acceptor
1 4 acceptor
1 5 acceptor
1 6 acceptor
6 7 8 9 10 11 12 rings
20
4
0
4
0
0
0
0
1
1