1973458 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 16 8 7 7 7 7 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 6 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 1 2 2 3 3 4 4 4 5 6 7 7 7 7 8 8 9 9 9 10 10 10 11 11 12 12 13 13 14 14 15 16 17 17 18 18 19 19 19 24 24 24 21 24 8 12 20 21 20 38 39 22 23 8 9 25 26 27 28 19 29 30 11 13 14 17 18 15 16 15 31 16 32 33 34 20 22 21 23 35 36 37 40 41 42 1 1 1 1 2 1 1 1 1 3 3 1 1 1 1 1 1 1 1 1 1 2 1 2 1 2 1 1 1 2 1 1 1 1 1 2 1 1 1 1 1 1 1 2 5 10 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 -4.3853 3.9493 -4.3522 -4.6024 -1.3961 -0.6896 6.1034 4.7769 7.0393 -0.1511 -1.5799 2.5951 0.6824 0.3933 2.0603 1.7713 -2.3983 -2.1621 8.3459 -3.7608 -3.5352 -1.843 -1.346 -5.5149 6.577 5.915 4.3242 4.9459 6.5548 7.2537 0.2735 -0.2421 2.6705 2.1914 9.0016 8.1675 8.8729 -4.3487 -5.5902 -6.2295 -6.069 -4.9526 2.7062 -0.7597 0.0593 -2.2913 -3.7241 3.1801 0.2071 -0.2108 0.8224 -0.3539 -0.2123 -0.6257 -0.4431 -0.4011 -0.5796 -0.5375 -1.3403 1.0531 1.2777 -1.1529 1.1336 -2.661 2.2319 2.622 -0.6635 0.9209 0.6805 -0.9682 1.6821 0.0916 -0.414 -0.3329 -0.6744 -0.5737 1.7136 2.0355 0.4365 -3.1217 -2.1094 1.8045 3.5613 2.4712 -0.4404 0.6261 -0.3898 -0.3786 0.0331 -0.0015 0.2284 -0.3901 -0.808 0.1245 -0.0504 0.4604 -0.9903 1.4079 -0.8218 1.5766 -0.1295 -0.1428 -0.1781 -0.2972 -0.31 -0.0393 -0.0645 0.9752 0.6992 1.0403 -0.844 -1.1644 -1.2855 -1.5964 -1.9976 2.2878 -1.7147 2.5776 -0.9383 0.5915 0.2832 0.1419 -0.5105 0.8478 1.0505 1.9007 Conformer ID 11 2.1 PubChem ncbi.nlm.nih.gov 2009.12.11 001E1CD200000001 Energy MMFF94 NoEstat 7 1.7.2 Szybki openeye.com 2012.11.26 73.4053 Feature Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 45.671 Fingerprint Shape 2 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 10411042 1 17905890628222517967 10595046 47 18334572435153831650 10730089 173 18409449189768881740 10906281 52 18200604600434291284 11315181 36 17895474829785500470 12107183 9 17613708225143593202 12236239 1 17749103362086865931 12390115 104 18271530806034619817 12403259 415 17775276183892174698 12895837 130 18260839223812670892 13140716 1 18412262836014580857 13631057 29 17604713416179041403 13911987 19 18192132825405373813 14790565 3 18124319311601031889 17980427 23 18114187444946408388 19427546 20 18334290985667025295 20600515 1 18342184323703500013 20871999 31 18412819192443720023 21033648 29 17632279191052804136 21267235 1 18337392767972351371 21792961 116 17560807598305902334 2297311 6 18342178899016840734 23402539 116 18411974750180712391 23557571 272 18272091621320729420 23559900 14 18341607174782571138 335352 9 18410847786235024783 34797466 226 18059022791150849124 445580 37 18336274513681984244 5265222 85 18200593722121121710 6327066 14 18116706314781081349 7808743 9 18337950069785439145 Shape Multipoles 8 1.8.3 OEShape openeye.com 2012.11.26 471.96 15.23 3.2 1 33.2 0.23 -0.24 -8.9 1.65 -5.32 0.05 0.27 0 -0.87 Shape Self Overlap 7 2.1 PubChem ncbi.nlm.nih.gov 2012.11.26 985.498 Shape Volume 7 1.8.3 OEShape openeye.com 2012.11.26 269.5 Conformer RMSD 7 2009.12.11 0.8 Diverse Conformer ID List 6 2012.02.08 1 12 9 18 17 8 15 3 5 2 6 7 13 14 4 16 10 11 Charge MMFF94 Partial 2 1.7.6 OEChem openeye.com 2012.02.08 25 1 -0.33 12 0.08 13 -0.15 14 -0.15 15 -0.15 16 -0.15 17 0.07 18 0.07 2 -0.36 20 0.41 21 0.41 22 0.48 23 0.48 24 0.23 3 -0.62 31 0.15 32 0.15 33 0.15 34 0.15 38 0.4 39 0.4 4 -0.9 5 -0.56 6 -0.56 8 0.28 Count Effective Rotor 7 1.7.6 OEChem ncbi.nlm.nih.gov 2012.01.18 6 Features Pharmacophore 2 ImplicitMillsDean merged 1.8.1 OEShape openeye.com 2012.02.08 9 1 19 hydrophobe 1 2 acceptor 1 24 hydrophobe 1 4 donor 1 5 acceptor 1 6 acceptor 3 3 4 20 cation 6 10 12 13 14 15 16 rings 6 3 11 17 18 20 21 rings 24 0 0 0 0 0 0 0 1 2