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Compound Summary for: CID 178052


Also known as: Abt-089; ABT 089; CHEMBL127071; Pozanicline (USAN); UNII-CL2002R563; AC1L434V; PDSP1_001326; PDSP2_001310; 161417-03-4
Molecular Formula: C11H16N2O   Molecular Weight: 192.25754   InChIKey: YRVIKLBSVVNSHF-JTQLQIEISA-N
ABT-089 is a neuronal nicotinic acetylcholine receptor agonist that may have therapeutic utility for the treatment of several neurological disorders including Alzheimer, Attention Deficit Hyperactivity Disorder and Schizophrenia/Schizoaffective disorders. In radioligand binding studies, ABT-089 has shown selectivity toward the alpha4beta2 nAChR subtype as compared to the alpha7 and alpha1beta1deltagamma nAChR subtypes. Neuronal nicotinic acetylcholine receptors (nAChRs) modulate the release of several important neurotransmitters, such as acetylcholine and dopamine.   From: DrugBank
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