Methotrexate - Compound Summary (CID 165528)
Also known as: Methotrexate hydrate, L-Amethopterin hydrate, Antifolan hydrate, MTX hydrate, Methylaminopterin hydrate, 4-Amino-10-methylfolic acid hydrate
Molecular Formula: C20H24N8O6   Molecular Weight: 472.45456   InChIKey: FPJYMUQSRFJSEW-ZOWNYOTGSA-N
An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.   From: MeSH
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