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Compound Summary for: CID 16158208

linaclotide

Also known as: Linzess; Linaclotide (USAN); Linaclotide [USAN]; 851199-59-2; Linaclotide [INN]; Linzess (TN); CHEBI:68551; DB08890
Molecular Formula: C59H79N15O21S6   Molecular Weight: 1526.73646   InChIKey: KXGCNMMJRFDFNR-WDRJZQOASA-N
Linaclotide is an orally administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids. The protein sequence is as follows: Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr. There are three disulfide bonds which are located between Cys1 and Cys6; between Cys2 and Cys10; and between Cys5 and Cys13. FDA approved on August 30, 2012.    From: DrugBank
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