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Compound Summary for: CID 16132416

Ularitide

Also known as: Urodilatin, Atriopeptin (95-126), Anf (95-126), Anp (95-126), Atrial natriuretic peptide (95-126)
Molecular Formula: C145H234N52O44S3   Molecular Weight: 3505.92646   InChIKey: IUCCYQIEZNQWRS-DWWHXVEHSA-N
Ularitide is a synthetic form of urodilatin, a naturally occurring human natriuretic peptide that is involved in regulating blood pressure and the excretion of water and sodium from the kidneys. Urodilatin is produced in the kidney and excreted into the urine, and thus exists in low levels naturally in the systemic blood circulation. When injected into the blood, ularitide appears to cause diuresis (urine output) and natriuresis (sodium excretion), as well as vasodilation. Ularitide is currently in Phase 2 development as a potential treatment for patients with acute decompensated heart failure (ADHF).   From: DrugBank
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