15128244
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
8
8
8
8
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
5
5
5
6
6
6
6
7
7
8
8
9
10
10
11
11
11
12
13
13
14
16
16
16
17
17
17
18
18
18
19
19
19
20
20
20
9
18
12
20
15
16
15
7
29
30
7
8
21
22
11
23
9
10
14
12
24
25
26
27
13
14
15
28
17
31
32
19
33
34
35
36
37
38
39
40
41
42
43
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
2
2
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
7
5
6
11
23
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
-1.5505
0.2731
2.8548
2.7092
-5.6058
-3.4817
-4.1772
-1.9926
-1.1075
-1.539
-3.6118
-0.1667
0.7352
0.2648
2.1718
4.2807
4.8519
-1.7752
6.3673
0.499
-3.9049
-3.7142
-4.0145
-2.2336
-3.7034
-4.1425
-2.5555
0.9473
-5.8125
-6.0471
4.5478
4.6709
4.4298
4.5349
-2.2382
-0.8236
-2.4465
6.8095
6.7506
6.7037
0.8893
-0.4397
1.2337
2.4676
-2.7248
0.351
-1.5631
-0.0935
0.366
-0.3099
0.1167
1.182
-1.1905
0.2076
-1.438
-0.3755
0.9346
-0.612
0.2286
1.3842
3.1604
1.3285
-3.42
-0.013
1.4371
-1.3929
-2.0236
1.297
-0.2325
-0.0535
1.7805
0.9031
-0.5199
-0.7271
0.2529
1.3696
2.3352
4.1237
3.343
2.5977
1.3817
2.1697
0.4018
-4.4134
-3.5355
-2.8945
-0.2556
-0.6167
0.1886
-1.0819
0.7866
-0.3694
0.8226
-0.4021
-0.3434
-0.4928
2.1415
-0.5256
-0.4673
-0.376
-0.5014
0.2269
1.0342
-1.4817
1.1058
0.6076
-1.31
-0.3553
0.7846
-0.5539
2.2199
2.994
2.2625
-0.3423
0.8439
1.6004
0.6927
-0.7971
2.0462
0.5897
-1.2507
-1.9907
-2.1381
0.1058
1.6916
1.5816
0.3702
1.1587
1.2258
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
00E6D6B400000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
62.2951
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
35.526
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10493431 412 18272090530029875091
106641 1 18339645663065604939
11132069 177 18410019844550695287
11578080 2 18128254485402396273
12403259 415 18341332193807266948
12633257 1 18270394018533836088
12892183 10 17822565019815233594
12930653 34 18263077717279401533
13140716 1 18193559093142530129
13540713 4 18119811309425493477
14178342 30 17897447194378720844
14223421 5 18118688712443531119
14787075 74 18131346449005190905
15042514 8 18263080088360142874
15048467 5 17346884459420499041
15209294 21 17846503642335078320
16945 1 18334865974261004375
19784866 240 15068339003893690296
200 152 13767923533253175420
20344682 10 18335145284489710711
20510252 161 18341890758156155520
20645477 56 18341325669862661860
21033648 29 18268127852076015096
21069387 34 12035741919886144115
21637258 2 15430312602802407723
22182313 1 18337674092334901100
22224240 67 18341613750277541035
2334 1 18122068868959231551
23402539 116 18268696380753610382
23557571 272 17532102592130530551
23559900 14 17751933410517243399
2748010 2 17977390434524346695
3187 122 17967811630715145909
34934 24 18411132507832659391
350125 39 18266467507760083662
5104073 3 18264772056091974505
58807428 26 18409444808591322018
81228 2 17908120424364214750
9981440 41 18118940543239674633
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
383.13
10.16
2.93
1.31
9.63
0.75
-0.48
-4.51
-6.05
-0.02
0.8
-0.62
-0.29
1.41
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
776.712
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
225
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
89
174
166
29
203
84
210
169
95
113
173
156
205
24
40
206
119
167
102
26
195
19
153
204
214
78
57
101
148
196
98
219
18
50
152
94
200
103
197
199
213
32
96
183
154
76
88
175
217
25
125
144
82
56
38
114
22
145
135
209
13
6
70
69
130
178
202
100
75
191
122
42
161
110
177
104
190
86
216
120
54
187
49
9
138
4
118
158
124
211
14
146
90
157
48
218
149
168
85
59
106
207
28
61
201
20
41
34
155
30
126
172
16
3
43
21
194
198
181
193
31
53
142
111
165
92
160
68
10
35
163
189
44
71
77
136
115
5
164
80
99
176
141
7
52
117
72
127
192
23
11
107
33
132
97
128
83
12
143
47
36
116
8
184
171
73
186
131
58
60
2
170
66
133
91
147
185
105
151
63
208
79
39
182
112
15
121
162
159
129
65
51
180
81
17
64
108
220
179
123
46
137
55
67
27
150
87
188
109
45
134
212
139
37
140
62
215
93
74
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
21
1 -0.36
10 -0.15
12 0.08
13 0.09
14 -0.15
15 0.63
16 0.28
18 0.28
2 -0.36
20 0.28
24 0.15
28 0.15
29 0.36
3 -0.43
30 0.36
4 -0.57
5 -0.99
6 0.14
7 0.27
8 -0.14
9 0.08
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
7
1 1 acceptor
1 19 hydrophobe
1 2 acceptor
1 4 acceptor
1 5 cation
1 5 donor
6 8 9 10 12 13 14 rings
20
1
0
1
0
0
0
0
1
1