Nitric Oxide - PubChem

Nitric Oxide - Compound Summary (CID 145068) Also known as: Mononitrogen monoxide, INOmax, nitrogen monooxide, Nitrosyl radical, Amidogen, oxo-, Nitric oxide trimer, nitrosyl, oxoazanyl Molecular Formula: NO Molecular Weight: 30.0061 InChIKey: MWUXSHHQAYIFBG-UHFFFAOYSA-N A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 2D SDF: Display 2D SDF: Save BioActivity, this compound BioActivity, with similar compounds
Show subcontent titlesHide subcontent titlesTable of Contents Identification Depositor-Supplied Synonyms Compound Information Related Records Related Compounds with Annotation Related Compounds Related Substances Use and Manufacturing Medication Information Patents Methods of Manufacturing Formulations/Preparations Pharmacology Pharmacological Action Therapeutic Uses Biomedical Effects and Toxicity Absorption, Distribution and Excretion Metabolism/Metabolites Mechanism of Action Interactions Toxicity Summary Antidote and Emergency Treatment Medical Surveillance Human Toxicity Excerpts Non-Human Toxicity Excerpts Toxicology References Safety and Handling Safety References DOT Emergency Guidelines Fire Potential Toxic Combustion Products Reactivities and Incompatibilities Decomposition Odor Threshold Skin, Eye, and Respiratory Irritations Protective Equipment and Clothing Other Preventative Measures Shipment Methods and Regulations Storage Conditions Cleanup Methods Disposal Methods Environmental Fate and Exposure Potential Artificial Sources Environmental Fate Atmospheric Concentrations Probable Routes of Human Exposure Exposure Standards and Regulations Immediately Dangerous to Life or Health OSHA Standards NIOSH Recommendations Threshold Limit Values State Drinking Water Guidelines CERCLA Reportable Quantities RCRA Requirements Monitoring and Analysis Methods Sampling Procedures Analytic Laboratory Methods Literature Depositor Provided PubMed Citations NLM Curated PubMed Citations Biomolecular Interactions and Pathways Protein Bound 3-D Structures Biosystems and Pathways Interactions Target Action General Function Specific Function Gene Name GenBank Gene GenBank Protein References Biological Test Results BioAssay Results Classification Ontologies Substance Categorization Classification Chemical and Physical Properties Color/Form Odor Boiling Point Melting Point Critical Temperature and Pressure Density/Specific Gravity Heat of Vaporization Solubilities Spectral Properties Vapor Density Vapor Pressure Viscosity Other Chemical/Physical Properties Computed Properties Expand all sub-sections	2D Structure 3D Conformer
Identification Help top of page Related Records Help top of page show all 3 sub-sections (Related Compounds with Annotation, Related Compounds, Related Substances)show first sub-section only Use and Manufacturing Help top of page show all 4 sub-sections (Medication Information, Patents, Methods of Manufacturing, Formulations/Preparations)show first sub-section only Pharmacology Help top of page show all 2 sub-sections (Pharmacological Action, Therapeutic Uses)show first sub-section only Biomedical Effects and Toxicity Help top of page show all 10 sub-sections (Absorption, Distribution and Excretion, Metabolism/Metabolites, Mechanism of Action ...)show first sub-section only Safety and Handling Help top of page show all 14 sub-sections (Safety References, DOT Emergency Guidelines, Fire Potential, Toxic Combustion Products ...)show first sub-section only Environmental Fate and Exposure Potential Help top of page show all 4 sub-sections (Artificial Sources, Environmental Fate, Atmospheric Concentrations, Probable Routes of Human Exposure)show first sub-section only Exposure Standards and Regulations Help top of page show all 7 sub-sections (Immediately Dangerous to Life or Health, OSHA Standards, NIOSH Recommendations ...)show first sub-section only Monitoring and Analysis Methods Help top of page show all 2 sub-sections (Sampling Procedures, Analytic Laboratory Methods)show first sub-section only Literature Help top of page show all 2 sub-sections (Depositor Provided PubMed Citations, NLM Curated PubMed Citations)show first sub-section only Biomolecular Interactions and Pathways Help top of page show all 3 sub-sections (Protein Bound 3-D Structures, Biosystems and Pathways, Interactions)show first sub-section only Biological Test Results Help top of page Data Analysis Data Download BioActivity Summary: This Compound with Similar Compounds with Similar Conformers Classification Help top of page show all 2 sub-sections (Ontologies, Substance Categorization Classification)show first sub-section only Chemical and Physical Properties Help top of page show all 14 sub-sections (Color/Form, Odor, Boiling Point, Melting Point, Critical Temperature and Pressure ...)show first sub-section only

_