Methotrexate - PubChem

Methotrexate - Compound Summary (CID 126941) Also known as: Amethopterin, Rheumatrex, Mexate, Abitrexate, Methylaminopterin, Ledertrexate, Metatrexan, Antifolan, Trexall Molecular Formula: C₂₀H₂₂N₈O₅ Molecular Weight: 454.43928 InChIKey: FBOZXECLQNJBKD-ZDUSSCGKSA-N An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA. From: MeSH View the conformer with web-based 3D viewer View the conformer with Pc3D viewer application Download Pc3D viewer application 2D ASN.1 Text: Display 2D ASN.1 Text: Save 2D ASN.1 Binary: Save 3D ASN.1 Text: Display 3D ASN.1 Text: Save 3D ASN.1 Binary: Save 2D XML: Display 2D XML: Save 3D XML: Display 3D XML: Save 2D SDF: Display 2D SDF: Save 3D SDF: Display 3D SDF: Save BioActivity, this compound BioActivity, with similar compounds BioActivity, with similar conformers
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