124137
1
2
3
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5
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7
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9
10
11
12
13
14
15
16
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19
20
21
22
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27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
17
17
8
8
8
8
8
8
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
3
4
4
5
5
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20
20
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22
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23
24
24
25
25
26
26
27
28
28
18
27
14
15
11
36
12
37
13
38
16
44
16
14
17
35
29
48
49
12
13
30
14
31
15
32
33
16
34
18
19
21
22
39
21
22
23
40
41
24
42
43
25
26
27
45
28
46
29
29
47
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
2
1
2
1
1
1
1
1
1
1
2
1
1
1
2
1
2
1
1
11
4
13
12
30
2
1
12
5
14
11
31
2
1
13
6
11
15
32
1
1
14
3
9
12
33
1
1
15
3
13
16
34
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
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29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
-0.1968
-6.8411
2.7719
6.5868
4.3692
6.1487
4.2816
2.5578
1.7997
-6.78
5.381
4.2165
5.1702
2.8741
3.7726
3.4483
0.4995
-0.5279
0.17
-2.1317
-1.8296
-1.1318
-3.5233
-4.3926
-5.1284
-4.4288
-5.9284
-5.2287
-5.9786
5.5293
4.271
5.3333
2.8253
3.6405
1.9823
7.3273
4.2982
7.0186
0.8994
-2.6108
-1.3542
-3.5017
-4.0023
4.0858
-5.0855
-3.8492
-5.2583
-7.329
-6.8026
-3.2836
-0.0527
0.6121
-0.917
-2.6343
1.768
3.7433
3.0022
-1.5146
2.657
-0.4708
-1.3389
1.0001
-0.7363
1.4563
2.7905
-1.4944
-2.2644
-0.6816
-1.41
-2.2224
-0.6396
-1.3644
-0.3
-0.6179
0.9641
0.3621
1.9442
1.6432
-0.5911
-1.4586
1.1557
-0.7713
1.5196
-2.0517
-0.4435
-2.5445
1.5518
-0.0484
-2.8228
-0.0004
-1.213
-2.3466
4.6276
-1.6183
1.2079
2.9382
2.4565
3.5803
-1.9221
-2.2011
-0.3334
-0.4463
0.2778
0.5206
0.1206
-1.1737
-0.4567
-0.8163
0.1773
-0.3009
-0.179
0.1208
0.2258
-0.3639
0.0166
-0.5672
1.1196
1.0249
-0.0679
1.6186
1.5591
0.9202
-0.2068
1.4798
-0.7942
0.8925
-0.2447
1.2582
-1.39
-1.2533
1.217
1.3129
-1.2973
-0.0315
1.2434
0.1449
1.6156
-0.5288
2.4691
2.6474
1.4411
-0.2562
-0.6297
2.3653
1.3316
-1.6417
-0.4047
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0001E4E900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
92.8477
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
86.361
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10763959 59 18333736801436075220
10811444 77 18411136922468261149
11089746 13 18334575737240000611
12422481 6 17967818275076635869
12596602 18 13334751132081459973
12633257 1 15719674384640016850
13583140 156 18187376444855317963
13878862 14 18335124415333355532
13941219 33 9295294954621451215
14117953 113 18271529694166111270
14251764 30 9871746893235134991
14251764 38 18411709759510484513
14556957 393 17274829017530932897
14739800 52 17822561734207580521
14767858 380 17561078120931619239
15142383 8 18113051632893245250
15183329 4 18410855430089862275
15238133 3 17894923948948526902
15461852 350 16415479355354933390
15510800 12 13182436925354538845
17780758 139 11530485519877174775
17844677 252 18263095451247086603
18335252 114 18337102372005338095
20511986 3 18059567040500405738
20715895 44 18340772554698481449
21033648 144 18333731321453321087
21033648 29 16588020178867884239
21033650 10 15409244796247173546
21298829 104 18341617031717249984
21859007 373 18335978688702851956
22122407 14 18335991904026695043
22950370 63 7853568002868514947
23559900 14 18410300194251652394
2838139 119 18408603648062681357
314194 84 8213851544941240715
33382 64 10159699096765499327
3737641 26 9871753481635884733
4017518 198 17418103088144658798
4144715 1 18042138694003939346
46939830 39 17604162474991363268
57724786 102 17387419149985772660
6371009 1 18272368633489180248
6371380 46 18186241723681611770
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
555.37
18.19
3.62
1.48
5.54
1.45
0.21
10.95
3.94
-2.58
1.13
2.41
-0.4
0.06
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1174.064
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
311.4
Conformer
RMSD
7
2009.12.11
1
Diverse Conformer
ID List
6
2012.02.08
1
96
274
107
251
18
91
188
258
78
99
81
165
231
134
20
167
98
111
102
276
9
136
89
123
245
156
141
162
43
138
154
247
160
260
224
137
170
203
269
6
175
178
26
128
62
130
267
163
177
37
75
152
139
8
275
142
49
254
110
157
241
192
53
120
124
219
125
40
24
277
126
127
196
199
31
54
257
238
65
206
86
33
117
114
208
21
252
66
190
133
23
144
95
149
159
93
183
158
83
122
92
235
22
176
248
94
147
210
180
104
74
13
212
186
181
211
218
105
115
72
166
228
39
240
109
5
195
42
15
215
97
217
200
60
255
185
12
227
239
3
263
262
271
226
232
129
28
161
58
84
205
140
87
174
148
202
47
76
189
36
121
118
155
85
25
50
145
220
201
233
209
204
17
82
143
256
249
52
14
41
131
73
229
19
70
223
10
213
242
71
16
216
11
221
132
151
169
27
103
69
2
184
32
191
77
234
244
150
193
101
80
168
270
48
57
164
44
225
38
266
153
88
79
7
119
253
237
63
4
179
273
59
51
56
172
34
108
61
173
55
246
243
182
29
106
207
113
214
259
197
264
45
261
35
68
100
112
146
194
116
268
230
250
30
187
236
90
67
64
198
46
135
222
171
272
265
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.05.21
42
1 -0.18
10 -0.9
11 0.28
12 0.28
13 0.28
14 0.65
15 0.34
16 0.66
17 0.1
18 0.18
19 -0.15
2 -0.18
20 -0.14
21 -0.15
22 -0.15
23 0.29
24 -0.14
25 -0.15
26 -0.15
27 0.18
28 -0.15
29 0.1
3 -0.56
35 0.4
36 0.4
37 0.4
38 0.4
39 0.15
4 -0.68
40 0.15
41 0.15
44 0.5
45 0.15
46 0.15
47 0.15
48 0.4
49 0.4
5 -0.68
6 -0.68
7 -0.65
8 -0.57
9 -0.87
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
6.2
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.05.21
17
1 10 cation
1 10 donor
1 3 acceptor
1 4 acceptor
1 4 donor
1 5 acceptor
1 5 donor
1 6 acceptor
1 6 donor
1 7 acceptor
1 8 acceptor
1 9 cation
1 9 donor
3 7 8 16 anion
6 17 18 19 20 21 22 rings
6 24 25 26 27 28 29 rings
6 3 11 12 13 14 15 rings
29
5
5
0
0
0
0
0
1
1