etoricoxib - Compound Summary (CID 123619)
Also known as: Arcoxia, Tauxib, Nucoxia, Algix, Etoricoxibe, 202409-33-4, MK-663, MK 0663, MK-0663
Molecular Formula: C18H15ClN2O2S   Molecular Weight: 358.8419   InChIKey: MNJVRJDLRVPLFE-UHFFFAOYSA-N
Etoricoxib is a new COX-2 selective inhibitor. Current therapeutic indications are: treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, chronic low back pain, acute pain and gout. Like any other COX-2 selective inhibitor, Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2). This reduces the generation of prostaglandins (PGs) from arachidonic acid.   From: DrugBank
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