1158
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
15
15
8
8
8
8
8
8
8
8
8
8
8
8
7
7
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
2
3
3
4
4
5
5
6
7
9
11
12
13
15
15
15
16
16
16
17
17
17
18
18
19
19
20
21
21
23
23
24
24
6
8
9
10
8
12
13
14
19
20
17
32
18
33
21
22
37
25
38
39
20
22
23
22
25
35
18
19
26
20
27
21
28
29
30
31
24
34
25
36
1
1
1
2
1
1
1
2
1
1
1
1
1
1
1
2
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
1
1
1
17
4
18
19
26
3
1
18
5
17
20
27
3
1
19
3
17
21
28
3
1
20
3
15
18
29
3
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
-3.8881
-5.4223
1.1281
-0.9355
1.5735
-2.4562
4.4537
-4.9447
-3.8269
-4.238
6.8432
-6.6065
-6.2083
-4.3232
3.2833
5.642
-0.1461
1.3141
-0.0831
2.0014
-1.2681
4.4523
3.3688
4.5102
5.7765
-0.5515
1.6082
-0.0153
2.1373
-1.1626
-1.3302
-0.8445
1.3054
2.4422
6.4944
4.5375
-3.3635
-7.0105
-6.5317
1.3281
-0.734
0.8481
-1.548
-2.675
0.7609
-1.46
0.7716
2.913
0.9956
1.0193
-0.508
-1.1883
-1.6545
0.0278
-0.2239
-1.0297
-1.3917
0.4854
-0.2956
1.1621
-0.6142
0.9702
1.3318
0.7089
-1.3911
-1.4059
0.8237
-0.587
2.2509
0.8945
-2.516
-2.6748
1.4205
-0.6725
2.0661
3.5064
-1.29
-2.1117
0.6263
-0.8046
0.811
-0.8672
0.5722
0.1317
1.6277
-0.4635
0.3077
2.048
-1.4364
-1.881
0.5327
-1.2465
0.2583
0.1017
0.1858
0.0316
0.1299
0.8341
0.7946
0.7307
-0.7602
-1.35
-0.9148
1.1387
-1.0244
-0.9124
1.8823
0.739
1.8554
-0.8496
1.5068
-1.0967
0.4254
-2.1457
0.9365
-2.3139
0.6029
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0000048600000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
3.7153
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
81.255
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10090160 65 18114466682034186690
10366900 7 18411980273872580873
10670039 82 18272653437076029525
10912923 1 18335701594154823272
11089746 13 13479132427862321389
11315621 246 17988641939117486751
11488393 25 16843906169208869222
12236239 1 18408605842648590304
12954195 1 17704081693760574951
13583140 156 16660369211599916881
13631057 29 18271804670693687723
14251757 5 18200028598444828511
14251764 30 15410895167278829381
14528608 73 18408605863960117316
14767858 380 18410574011090203213
15183329 4 18272089413438598862
16079462 125 15430032175523546732
17980427 23 17968109585945374141
19377110 9 18410581652190379513
21033648 29 14707209962959111372
21054139 6 18412539924911602455
21150785 3 18261395589069154196
21267235 1 18059855125880073903
21315759 148 15339117966118150447
2303208 19 15985106309896173692
23081809 10 18335140851988756248
23402539 116 18040433253117351713
25147074 1 18340484461103645987
34797466 226 16773512265439331800
4325135 7 18411140233956299725
59755656 215 17489871544134445023
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
441.79
16.66
2.03
1.41
3.97
0.06
-0.06
-1.44
-5.58
1.02
0.17
0.45
-0.03
-2.68
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
888.162
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
260.2
Conformer
RMSD
7
2009.12.11
1.2
Diverse Conformer
ID List
6
2012.02.08
1
126
241
418
47
174
161
137
329
12
91
145
326
400
22
93
64
303
478
308
77
417
405
456
490
79
52
501
163
42
160
106
273
59
201
306
2
6
462
127
385
25
242
92
151
209
411
533
65
318
404
73
234
328
164
291
99
61
36
14
395
3
17
392
537
139
382
49
85
128
44
389
196
192
23
13
68
365
256
104
468
425
83
194
446
231
220
313
141
131
210
40
243
113
248
410
217
5
167
204
86
35
10
80
4
112
224
88
62
97
197
488
56
9
287
115
28
72
8
269
155
388
276
429
406
460
16
124
415
11
215
279
136
19
221
452
516
78
50
448
322
55
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
33
1 1.51
10 -0.7
11 -0.57
12 -0.77
13 -0.77
14 -0.7
15 -0.47
16 -0.49
17 0.28
18 0.28
19 0.28
2 1.51
20 0.58
21 0.28
22 0.69
23 -0.04
24 -0.14
25 0.62
3 -0.56
32 0.4
33 0.4
34 0.15
35 0.37
36 0.15
37 0.5
38 0.5
39 0.5
4 -0.68
5 -0.68
6 -0.55
7 -0.57
8 -0.54
9 -0.77
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
7
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
16
1 10 acceptor
1 11 acceptor
1 12 acceptor
1 13 acceptor
1 14 acceptor
1 16 donor
1 3 acceptor
1 4 acceptor
1 4 donor
1 5 acceptor
1 5 donor
1 7 acceptor
1 9 acceptor
4 2 12 13 14 anion
5 3 17 18 19 20 rings
6 15 16 22 23 24 25 rings
25
4
0
4
0
0
0
0
1
3