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Compound Summary for: CID 110635


Also known as: Cialis; 171596-29-5; Ic351; ADCIRCA; Tadanafil; IC 351; ICOS 351; IC-351; UNII-742SXX0ICT
Molecular Formula: C22H19N3O4   Molecular Weight: 389.40396   InChIKey: WOXKDUGGOYFFRN-IIBYNOLFSA-N
Tadalafil is an orally adminstered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor. Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy. [Wikipedia]   From: DrugBank
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