107905
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
8
8
8
8
8
8
8
8
8
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
3
3
4
4
5
5
6
7
7
8
8
9
9
10
10
11
11
11
12
12
13
13
13
14
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15
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16
17
18
18
19
19
20
20
21
21
23
24
25
25
27
27
28
28
29
29
30
31
12
15
11
23
17
42
22
43
24
46
23
26
47
30
48
31
49
32
50
12
13
33
16
34
14
35
36
15
17
18
19
20
21
22
37
24
38
25
39
22
40
27
26
26
41
28
29
31
44
30
45
32
32
1
1
1
1
1
1
1
1
1
1
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
2
2
1
1
1
1
1
1
2
1
2
1
1
2
1
1
2
1
1
1
2
1
1
2
11
2
12
13
33
1
1
12
1
11
16
34
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
-1.4133
-0.2736
2.2462
1.5821
-3.7707
0.7055
-6.0581
3.3323
4.2054
4.7837
-0.9784
-2.0171
0.0153
0.4152
-0.3134
-3.0974
1.5248
0.0869
-2.9408
-4.2442
1.9148
1.1985
0.6948
-3.9334
-5.2369
-5.0814
1.7766
2.4837
2.0424
3.0601
3.5011
3.7894
-1.4776
-2.5134
-0.4723
0.909
-0.4766
-2.0451
-4.3754
2.7779
-6.126
2.9725
0.9746
2.2557
1.4904
-2.9192
-6.775
2.7301
3.8679
5.1761
-1.6739
0.5108
-3.3954
-4.8636
2.3588
1.2511
2.5757
0.768
4.321
3.0156
-0.5444
-1.1537
-1.6236
-2.4823
-2.4661
-0.1546
-3.3313
-3.2558
0.6547
-0.0468
-4.1297
-4.0886
1.1186
1.5737
0.8721
1.6824
1.622
2.7431
0.9513
1.4226
3.2145
2.5542
-0.1274
-2.0023
-2.28
-1.2118
-3.2222
0.5842
-0.6708
-4.7856
0.9468
-4.0326
-4.7094
3.2581
0.0637
2.1458
2.5106
0.0091
4.6427
3.8041
-0.5726
0.9183
2.0954
-2.3818
-2.3133
2.8657
-0.749
-2.4011
0.6897
-1.6836
1.5737
0.6228
1.9989
0.8294
-0.3667
0.2523
0.9393
-1.4478
-0.872
1.0375
-0.1365
-1.3307
1.6517
-1.2119
0.6975
-0.4271
0.768
1.1512
-0.4083
-1.2377
0.3215
-0.8729
2.4583
1.1165
2.7315
2.4756
-2.3774
-1.484
1.9174
-0.052
1.318
1.984
-3.1257
2.0804
-0.7005
-2.7323
-0.0948
-2.4874
1.5433
-1.2701
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0001A58100000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
96.2552
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
66.019
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
10165383 225 18268729353671085905
10190108 129 17982745370444851195
10369192 42 18188786062080869749
10675989 125 18271817799849984736
10721379 63 18266468598386143737
107951 10 18043264637224412450
11477941 20 17190973470464308134
11488393 25 18263654973969040811
11578080 2 17535793704236295651
11720765 8 17983008956054072956
11763715 3 16628836167630556915
12160290 23 17690819573654013043
12422481 6 17756103914150593562
12741549 16 17692228761029296937
12788726 201 17546144755212533450
133893 2 18193293904797747305
13681431 1 18053659175113229091
140371 6 18126007061732968323
151778 21 18409725153933383881
15210252 30 17543630825244547117
15463212 79 17902778992734233056
15664445 248 17905891379266522259
16988056 13 17761192342216442373
17357779 13 17337005124344216747
17899979 19 18115877300641817810
1813 80 17767962031129502235
18785283 64 18337945684987391675
20600515 1 17762046649760690987
21033648 29 18268153243442744288
21304303 282 17767089345050525990
21641784 216 17551809018676615102
21857420 4 17400343560623833349
23419403 2 17542281934968301995
23559900 14 18119518844302542931
24893989 43 15380973917114582396
25019877 29 17910410694627212727
26353 1 17693089665411521527
3298306 158 18409174320008715154
3411729 13 18261393313200697945
376196 1 18261110802635715897
4015057 19 16915397717112493976
4394409 98 18339378409258666942
44802255 64 17900005981923383492
46194498 28 18192988232645177637
5081480 168 17974286517726548725
5252454 2 18341047501894874113
5265222 85 18044680795690405756
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
599.85
9.1
6.32
2.24
10.12
5.19
-0.02
-12.66
-3.22
-7.71
-1.95
-0.86
0.39
0.97
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
1336.642
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
316.7
Conformer
RMSD
7
2009.12.11
0.8
Diverse Conformer
ID List
6
2012.02.08
1
21
42
76
44
60
78
67
46
75
71
56
33
72
64
65
40
34
55
13
23
69
2
74
53
43
73
39
32
70
47
51
31
36
5
66
77
41
15
49
11
38
59
35
62
14
63
16
12
6
4
61
52
58
9
7
50
19
37
3
48
80
17
8
26
54
28
30
45
22
57
18
79
68
10
27
29
20
25
24
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
46
1 -0.36
10 -0.53
11 0.28
12 0.42
13 0.14
14 -0.14
15 0.08
16 -0.14
17 0.08
18 -0.15
19 -0.15
2 -0.43
20 -0.15
21 -0.15
22 0.08
23 0.63
24 0.08
25 -0.15
26 0.08
27 0.09
28 -0.15
29 -0.15
3 -0.53
30 0.08
31 0.08
32 0.08
37 0.15
38 0.15
39 0.15
4 -0.53
40 0.15
41 0.15
42 0.45
43 0.45
44 0.15
45 0.15
46 0.45
47 0.45
48 0.45
49 0.45
5 -0.53
50 0.45
6 -0.57
7 -0.53
8 -0.53
9 -0.53
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
4.8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
13
1 1 acceptor
1 10 donor
1 3 donor
1 4 donor
1 5 donor
1 6 acceptor
1 7 donor
1 8 donor
1 9 donor
6 1 11 12 13 14 15 rings
6 14 15 17 18 21 22 rings
6 16 19 20 24 25 26 rings
6 27 28 29 30 31 32 rings
32
2
2
0
0
0
0
0
1
998