107609
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
8
8
8
7
6
6
6
6
6
6
6
6
6
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
2
3
4
4
4
5
5
5
6
6
6
7
7
7
10
10
10
10
11
11
12
12
12
13
13
13
9
11
8
9
5
8
19
6
9
14
7
15
16
8
17
18
11
12
20
21
22
23
13
24
25
26
27
28
1
1
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
5
4
6
9
14
1
1
2
5
10
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
0.9288
-4.4179
-0.4236
-2.5603
-1.3504
-1.6295
-2.6554
-3.3591
-0.2551
3.2998
2.069
4.5604
5.7934
-1.1508
-2.0884
-0.7458
-3.3588
-2.1685
-2.7945
3.1444
3.4141
2.1966
1.9092
4.7002
4.4539
5.9469
5.7
6.6843
-0.1185
0.4705
1.613
0.5054
-0.246
-1.5559
-1.1914
0.0111
0.5418
-0.3321
0.5279
0.3077
-0.5332
-0.3597
-2.2625
-2.0396
-2.0071
-0.8973
1.3357
-1.3266
-0.4939
1.5131
0.6531
1.3069
0.4317
-0.6468
-1.5308
-0.0574
0.444
-0.6632
-0.27
0.7618
0.9412
0.229
-0.8437
-0.2638
0.2968
0.1195
-0.1305
-0.4553
-0.1659
2.0104
0.9322
-0.1979
-1.0267
-1.7788
1.2972
-0.3173
1.1987
0.3332
-1.2078
-0.0264
-1.5391
0.912
-0.6069
-0.5876
Conformer
ID
11
2.1
PubChem
ncbi.nlm.nih.gov
2009.12.11
0001A45900000001
Energy
MMFF94 NoEstat
7
1.7.2
Szybki
openeye.com
2012.11.26
15.4192
Feature
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
25.372
Fingerprint
Shape
2
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
11062470 55 17603866710784051256
11315181 36 17918277567353575634
11401426 45 18407757049731326616
12815109 37 18411980261056126702
12932764 1 14129331961710554760
13214271 11 9079122154874150179
14123238 8 10807933765360199062
14577589 140 17988644124876187631
14911166 2 18408599271206137653
14943859 89 13406790034337312736
14993402 34 18410287021623267613
15048467 5 15285352895523397613
17834072 33 17703788176133572084
17834072 8 18334006186216932989
17834076 25 18410012126140835028
17870717 6 18059588987340040526
18186145 218 16515680104419435124
187816 3 18040715865853973537
200 152 17346877849391834190
20211469 26 17489870448906786128
20279233 1 17346888848982525038
20645476 183 17894627088898393243
20645477 56 13479132406350639530
20871999 31 18041840735021795867
21119208 17 18114181938908986916
22485316 2 18273494581183682646
23402539 116 18411413999176706620
23557571 272 18200600198826140100
23559900 14 17988914622111649336
4175511 318 18040996241250575847
42 15 11455899053010449588
449060 50 9799690398840677688
Shape
Multipoles
8
1.8.3
OEShape
openeye.com
2012.11.26
244.94
9.98
1.19
0.84
12.57
0.12
-0.03
1.12
2.05
-0.59
0.09
-0.39
0.05
-0.14
Shape
Self Overlap
7
2.1
PubChem
ncbi.nlm.nih.gov
2012.11.26
484.058
Shape
Volume
7
1.8.3
OEShape
openeye.com
2012.11.26
147.7
Conformer
RMSD
7
2009.12.11
0.6
Diverse Conformer
ID List
6
2012.02.08
1
105
102
18
185
13
217
218
97
160
120
118
15
82
5
42
24
28
133
53
132
112
83
20
196
108
131
189
106
86
69
84
107
173
8
103
213
11
123
157
43
204
145
3
146
85
100
208
125
158
38
212
48
155
128
33
201
46
17
95
52
79
153
68
12
172
209
22
165
191
101
124
66
167
94
96
183
143
88
113
65
136
139
216
31
90
77
169
14
192
80
19
50
4
60
87
39
141
61
190
170
129
30
205
177
21
117
140
178
91
75
187
63
127
200
176
154
26
36
72
134
25
29
6
45
71
130
194
56
186
55
98
54
110
92
137
162
27
23
184
74
203
70
202
159
59
34
40
188
150
180
142
109
32
10
174
148
111
47
210
16
44
37
114
64
104
49
7
119
179
164
76
2
175
93
147
211
149
9
67
193
152
51
126
116
135
78
115
198
57
215
182
81
207
166
195
156
121
122
99
144
138
181
163
171
35
62
41
206
73
89
58
151
161
219
168
199
197
214
Charge
MMFF94 Partial
2
1.7.6
OEChem
openeye.com
2012.02.08
10
1 -0.43
11 0.28
19 0.37
2 -0.57
3 -0.57
4 -0.73
5 0.36
7 0.06
8 0.57
9 0.66
Count
Effective Rotor
7
1.7.6
OEChem
ncbi.nlm.nih.gov
2012.01.18
5.8
Features
Pharmacophore
2
ImplicitMillsDean merged
1.8.1
OEShape
openeye.com
2012.02.08
5
1 13 hydrophobe
1 2 acceptor
1 3 acceptor
1 4 donor
5 4 5 6 7 8 rings
13
1
1
0
0
0
0
0
1
3