369 2 yourDSN yourDSN_Avian_Sarcoma_Virus_Src Literature data for small-molecule inhibitors of Avian Sarcoma Virus Src. This assay has minor changes. Various protocols were used; consult yourDSN and/or cited papers for details. A compound is listed as "Active" if IC50<100,000 nanomolar or Ki<100,000 nanomolar. If multiple measurements are available for a given compound, the compound is listed as "Active" if any of the measurements meet the criterion. Publications sometimes list an IC50, say, as greater than or less than some cutoff value; e.g., "IC50 >5000 nanomolar". IC50 is concentration of compound that yields 50% inhibition of the Src enzyme under the assay conditions. Ki is the enzymologic inhibition constant. 11876 Avian sarcoma virus 269446 Rous sarcoma virus http://www.yourDSN.org/bind/index.jsp The Binding Database 9046331 7510340 8027985 1 Ki_max This field is used if either or both of two situations occur: 1) If a publication gives Ki as "<x" 2) If multiple Ki measurements are available for a compound, in which case Ki_max is the largest Ki of the set. 1 6 2 Ki This field is used when a single Ki measurement is available for a compound and it is listed without a ">" or "<" symbol. 1 6 3 Ki_min This field is used if either or both of two situations occur: 1) If a publication gives Ki as ">x" 2) If multiple Ki measurements are available for a compound, in which case Ki_min is the smallest Ki of the set. 1 6 4 IC50_max This field is used if either or both of two situations occur: 1) If a publication gives IC50 as "<x" 2) If multiple IC50 measurements are available for a compound, in which case IC50_max is the largest IC50 of the set. 1 6 5 IC50 This field is used when a single IC50 measurement is available for a compound and it is listed without a ">" or "<" symbol. 1 6 6 IC50_min This field is used if either or both of two situations occur: 1) If a publication gives IC50 as ">x" 2) If multiple IC50 measurements are available for a compound, in which case IC50_min is the smallest IC50 of the set. 1 6 7 yourDSN Target Name Brief name of the assay target as used in yourDSN. 4 8 yourDSN Target Other Names Alternative name(s) of the assay target listed in yourDSN. 4 9 PubMed PubMed ID(s) for paper(s) from which data were extracted. If multiple IDs, they are separated by commas. 4 3 Tyrosine-protein kinase transforming protein Src (p60-Src) (v-Src) (pp60v-src). 125707 1 Avian sarcoma virus RASV1441 taxon 11894 0