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Phenylthiourea (CID 676454) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(5)
 
 
Inactive(436)
 
 
Inconclusive(23)
 
 
Unspecified(1)
 
 
Top Targets:
NR LBD PPAR(23)
 
 
 
NR LBD TR(16)
 
 
 
NR LBD ER(14)
 
 
 
NR LBD AR(14)
 
 
 
NR LBD VDR(10)
 
 
 
BioAssay Types:
Confirmatory(455)
 
 
 
Literature(10)
 
 
 
 
BioActivity Types:
Potency(383)
 
 
 
IC50(6)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 216    Data Row: 465   Total Pages: 24   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103565465]
IC50 1.5Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate by spectrometric analysis [AID626570, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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2
[SID103565465]
IC50 1.8Inhibition of tyrosinase in alpha-MSH-induced mouse B16 cells [AID494974, Type: Literature]
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3
[SID103565465]
IC50 1.8Inhibition of tyrosinase [AID457969, Type: Literature]
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4
[SID103565465]
IC50 1.8Inhibition of mushroom tyrosinase [AID331282, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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5
[SID103565465]
IC50 5.4Inhibition of melanogenesis in mouse B16 cells [AID480030, Type: Literature]
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6
[SID103565465]
IC50 100Inhibition of Haemophilus influenzae recombinant DapE [AID467024, Type: Literature]Succinyl-diaminopimelate desuccinylase [gi:1169224]
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7
[SID17388780]
Potency 2.6603qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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8
[SID17389761]
Potency 5.0119qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor: Activators of Intracellular cAMP Concentrations in Parental HEK 293 [AID938, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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9
[SID17389761]
Potency 5.9557qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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10
[SID17388780]
Potency 39.8107qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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11
[SID17388780]
Potency 39.8107qHTS assay for small molecule activators of the rat pregnane X receptor (rPXR) signaling pathway [AID651751, Type: confirmatory]pregnane X receptor [Rattus norvegicus] [gi:5702233]
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12
[SID144213315]
Potency-Replicate_1 68.5896qHTS assay for small molecule disruptors of the mitochondrial membrane potential - cell viability [AID720634, Type: confirmatory]
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13
[SID144213315]
Potency-Replicate_1 qHTS assay for small molecule disruptors of the mitochondrial membrane potential [AID720635, Type: confirmatory]
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14
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HepG2 cells [AID720674, Type: confirmatory]
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15
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HepG2 cells [AID720675, Type: confirmatory]
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16
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cells [AID720678, Type: confirmatory]
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17
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 590 nm (red) in HEK293 cells [AID720679, Type: confirmatory]
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18
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cells [AID720680, Type: confirmatory]
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19
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 460 nm (blue) in HEK293 cell free culture [AID720681, Type: confirmatory]
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20
[SID144213315]
Potency-Replicate_1 qHTS assay to test for compound auto fluorescence at 535 nm (green) in HEK293 cell free culture [AID720682, Type: confirmatory]
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