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BioActivity Data for Compound nitromethane (CID 6375)

Filters: All Data » confirmatory      
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BioActivity Outcomes:
Inactive(222)
 
 
Inconclusive(4)
 
 
Unspecified(8)
 
 
Top Targets:
NR LBD PPAR(9)
 
 
NR LBD TR(6)
 
 
NR LBD ER(6)
 
 
NR LBD AR(6)
 
 
P53(4)
 
 
BioAssay Types:
Confirmatory(220)
 
 
 
Literature(14)
 
 
 
BioAssay Categories:
Biochemical(4)
 
 
Cell-based(8)
 
 
Toxicity(34)
 
 
 
ADME(8)
 
 
BioActivity Types:
Potency(184)
 
 
 
IC50(12)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 230    Data Row: 234   Total Pages: 12   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179179]
IC50 100Cytotoxicity against human SW707 cells after 72 hrs by crystal violet staining method [AID736753, Type: Literature]
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2
[SID103179179]
IC50 100Cytotoxicity against human Capan1 cells after 72 hrs by crystal violet staining method [AID736754, Type: Literature]
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3
[SID103179179]
IC50 100Cytotoxicity against human CaSki cells after 72 hrs by crystal violet staining method [AID736755, Type: Literature]
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4
[SID103179179]
IC50 100Cytotoxicity against human Calu6 cells after 72 hrs by crystal violet staining method [AID736756, Type: Literature]
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5
[SID103179179]
IC50 100Cytotoxicity against human MeWo cells after 72 hrs by crystal violet staining method [AID736757, Type: Literature]
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6
[SID103179179]
IC50 100Cytotoxicity against human A431 cells after 72 hrs by crystal violet staining method [AID736758, Type: Literature]
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7
[SID103179179]
IC50 100Cytotoxicity against human Flow 2002 cells after 72 hrs by crystal violet staining method [AID736759, Type: Literature]
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8
[SID103179179]
IC50 100Cytotoxicity against human HaCaT cells after 72 hrs by crystal violet staining method [AID736760, Type: Literature]
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9
[SID103179179]
IC50 Inhibition of Staphylococcus aureus MurA2 expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis [AID736768, Type: Literature]
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10
[SID103179179]
IC50 Inhibition of Pseudomonas aeruginosa MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis [AID736769, Type: Literature]
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11
[SID103179179]
IC50 Inhibition of Escherichia coli MurA C115D mutant expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis [AID736770, Type: Literature]
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12
[SID103179179]
IC50 Inhibition of Escherichia coli MurA expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis [AID736771, Type: Literature]
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13
[SID144208020]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - wild type cell line [AID743012, Type: confirmatory]
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14
[SID144208020]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rev3 mutant cell line [AID743014, Type: confirmatory]
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15
[SID144208020]
Potency-Replicate_1 qHTS assay for identifying genotoxic compounds that show differential cytotoxicity against isogenic chicken DT40 cell lines with known DNA damage response pathways - Rad54/Ku70 mutant cell line [AID743015, Type: confirmatory]
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16
[SID144208020]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway - cell viability counter screen [AID743033, Type: confirmatory]
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17
[SID144208020]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway [AID743035, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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18
[SID144208020]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway [AID743036, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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19
[SID144208020]
Potency-Replicate_1 qHTS assay to identify small molecule agonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743040, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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20
[SID144208020]
Potency-Replicate_1 qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line - cell viability counter screen [AID743041, Type: confirmatory]
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