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nitromethane (CID 6375) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Inactive(214)
 
 
Inconclusive(4)
 
 
Unspecified(8)
 
 
Top Targets:
NR LBD PPAR(9)
 
 
NR LBD TR(6)
 
 
NR LBD ER(6)
 
 
NR LBD AR(6)
 
 
P53(4)
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
Literature(14)
 
 
 
BioActivity Types:
Potency(176)
 
 
 
IC50(12)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 222    Data Row: 226   Total Pages: 12   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179179]
IC50 100Cytotoxicity against human SW707 cells after 72 hrs by crystal violet staining method [AID736753, Type: Literature]
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2
[SID103179179]
IC50 100Cytotoxicity against human Capan1 cells after 72 hrs by crystal violet staining method [AID736754, Type: Literature]
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3
[SID103179179]
IC50 100Cytotoxicity against human CaSki cells after 72 hrs by crystal violet staining method [AID736755, Type: Literature]
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4
[SID103179179]
IC50 100Cytotoxicity against human Calu6 cells after 72 hrs by crystal violet staining method [AID736756, Type: Literature]
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5
[SID103179179]
IC50 100Cytotoxicity against human MeWo cells after 72 hrs by crystal violet staining method [AID736757, Type: Literature]
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6
[SID103179179]
IC50 100Cytotoxicity against human A431 cells after 72 hrs by crystal violet staining method [AID736758, Type: Literature]
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7
[SID103179179]
IC50 100Cytotoxicity against human Flow 2002 cells after 72 hrs by crystal violet staining method [AID736759, Type: Literature]
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8
[SID103179179]
IC50 100Cytotoxicity against human HaCaT cells after 72 hrs by crystal violet staining method [AID736760, Type: Literature]
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9
[SID103179179]
IC50 Inhibition of Staphylococcus aureus MurA2 expressed in Escherichia coli BL21(lambdaDE3) using UNAG and PEP as substrate incubated for 10 mins prior to PEP addition measured after 60 mins by spectrophotometric analysis [AID736768, Type: Literature]
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10
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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11
[SID17389787]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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12
[SID17389787]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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13
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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14
[SID17389787]
Potency qHTS Assay for Inhibitors and Activators of N370S glucocerebrosidase as a Potential Chaperone Treatment of Gaucher Disease [AID2101, Type: confirmatory]glucocerebrosidase [Homo sapiens] [gi:496369]
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15
[SID17389787]
Potency qHTS Assay for Inhibitors and Activators of Human alpha-Galactosidase From Spleen Homogenate [AID2107, Type: confirmatory]alpha-galactosidase [Homo sapiens] [gi:757912]
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16
[SID17389787]
Potency qHTS Assay for Allosteric/Competitive Inhibitors of Caspase-7 [AID889, Type: confirmatory]Caspase-7 [gi:1730092]
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17
[SID17389787]
Potency qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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18
[SID17389787]
JNK3 AlphaScreen Assay [AID530, Type: confirmatory]Mitogen-activated protein kinase 10 [gi:2499604]
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19
[SID17389787]
Potency qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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20
[SID17389787]
qHTS Assay for Inhibitors of RGS12 GoLoco Motif Activity (Red Fluorophore) [AID880, Type: confirmatory]RGS12 [Homo sapiens] [gi:3290016]
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