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BioActivity Data for Compound nitromethane (CID 6375)

Filters: All Data » confirmatory      
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BioActivity Outcomes:
Inactive(214)
 
 
Inconclusive(4)
 
 
Unspecified(8)
 
 
Top Targets:
NR LBD PPAR(9)
 
 
NR LBD TR(6)
 
 
NR LBD ER(6)
 
 
NR LBD AR(6)
 
 
P53(4)
 
 
BioAssay Types:
Confirmatory(212)
 
 
 
Literature(14)
 
 
 
BioAssay Categories:
Biochemical(4)
 
 
Cell-based(8)
 
 
Toxicity(34)
 
 
 
ADME(8)
 
 
BioActivity Types:
Potency(176)
 
 
 
IC50(12)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 222    Data Row: 226   Total Pages: 12   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179179]
IC50 100Cytotoxicity against human HaCaT cells after 72 hrs by crystal violet staining method [AID736760, Type: Literature]
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2
[SID103179179]
IC50 100Cytotoxicity against human Flow 2002 cells after 72 hrs by crystal violet staining method [AID736759, Type: Literature]
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3
[SID103179179]
IC50 100Cytotoxicity against human A431 cells after 72 hrs by crystal violet staining method [AID736758, Type: Literature]
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4
[SID103179179]
IC50 100Cytotoxicity against human MeWo cells after 72 hrs by crystal violet staining method [AID736757, Type: Literature]
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5
[SID103179179]
IC50 100Cytotoxicity against human Calu6 cells after 72 hrs by crystal violet staining method [AID736756, Type: Literature]
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6
[SID103179179]
IC50 100Cytotoxicity against human CaSki cells after 72 hrs by crystal violet staining method [AID736755, Type: Literature]
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7
[SID103179179]
IC50 100Cytotoxicity against human Capan1 cells after 72 hrs by crystal violet staining method [AID736754, Type: Literature]
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8
[SID103179179]
IC50 100Cytotoxicity against human SW707 cells after 72 hrs by crystal violet staining method [AID736753, Type: Literature]
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9
[SID17389787]
Potency qHTS assay for cell viability of the p53RE-bla HCT-116 cell line [AID743292, Type: confirmatory]
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10
[SID17389787]
Potency qHTS assay for cell viability of HEK293 cells [AID743288, Type: confirmatory]
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11
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule activators of the human pregnane X receptor (PXR) signaling pathway [AID720659, Type: confirmatory]pregnane X nuclear receptor [Homo sapiens] [gi:325495557]
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12
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity - cell viability counter screen [AID720653, Type: confirmatory]
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13
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway - cell viability counter screen [AID720652, Type: confirmatory]
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14
[SID17389787]
Potency-Replicate_1 qHTS assay for small molecule agonists of the antioxidant response element (ARE) signaling pathway measured by Nrf2-dependant transcriptional activity [AID720636, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 1 [Homo sapiens] [gi:20149576]
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15
[SID17389787]
Potency qHTS assay for small molecule antagonists of the retinoid-related orphan receptor gamma (ROR-gamma) signaling pathway [AID651802, Type: confirmatory]Nuclear receptor ROR-gamma [gi:49066040]
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16
[SID17389787]
Potency qHTS assay for small molecule agonists of the peroxisome proliferator-activated receptor alpha (PPARalpha) signaling pathway [AID651778, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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17
[SID17389787]
Potency qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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18
[SID17389787]
Potency qHTS assay to identify small molecules that stimulate Tumor Necrosis Factor-alpha (TNF-alpha) secretion [AID651757, Type: confirmatory]tumor necrosis factor [Homo sapiens] [gi:25952111]
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19
[SID17389787]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 5 hr assay [AID651755, Type: confirmatory]
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20
[SID17389787]
Potency qHTS assay for small molecule disruptors of the mitochondrial membrane potential - 1 hr assay [AID651754, Type: confirmatory]
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