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Tryptophan (CID 6305) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(14)
 
 
Inactive(375)
 
 
Inconclusive(47)
 
 
Unspecified(15)
 
 
Top Targets:
7tm 4(10)
 
 
NR LBD ER(9)
 
 
NR LBD AR(8)
 
 
NR LBD PPAR(8)
 
 
 
Pyruvate Kina..(8)
 
 
BioAssay Types:
Confirmatory(427)
 
 
 
 
 
Literature(24)
 
 
 
 
BioActivity Types:
Potency(367)
 
 
 
 
 
IC50(40)
 
 
 
 
EC50(6)
 
 
Ki(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 333    Data Row: 451   Total Pages: 23   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103241616]
Km 0.83Activity at Aspergillus fumigatus CdpNPT by HPLC analysis [AID422797, Type: Literature]
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2
[SID103241616]
IC50 3.5Antioxidant activity assessed as inhibition of HOCl-induced oxidation of DHR by rhodamine 123 staining [AID537676, Type: Literature]
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3
[SID90341602]
Potency 8.4368qHTS Assay for Inhibitors of Histone Lysine Methyltransferase G9a [AID504332, Type: confirmatory]euchromatic histone-lysine N-methyltransferase 2 [Homo sapiens] [gi:168985070]
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4
[SID50107108]
Potency 11.2202qHTS for differential inhibitors of proliferation of Plasmodium falciparum line 7G8 [AID1815, Type: confirmatory]
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5
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 3D7 after 72 hrs by SYBR green assay [AID524790, Type: Literature]
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6
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum 7G8 after 72 hrs by SYBR green assay [AID524791, Type: Literature]
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7
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum HB3 after 72 hrs by SYBR green assay [AID524795, Type: Literature]
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8
[SID103241616]
IC50 12.5892Antiplasmodial activity against Plasmodium falciparum W2 after 72 hrs by SYBR green assay [AID524796, Type: Literature]
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9
[SID26732620]
Potency 14.1254qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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10
[SID103241616]
IC50 19.2Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in presence of NaHCO3 [AID537680, Type: Literature]
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11
[SID144208444]
Potency-Replicate_1 30.669qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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12
[SID103241616]
IC50 31.9Antioxidant activity assessed as inhibition of peroxynitrite anion-induced oxidation of non-fluorescent DHR by rhodamine 123 staining in absence of NaHCO3 [AID537679, Type: Literature]
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13
[SID26732620]
Potency 50.1187qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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14
[SID103241616]
IC50 Inhibition of human recombinant KAT1 expressed in Sf9 cells [AID349604, Type: Literature]Kynurenine--oxoglutarate transaminase 1 [gi:46396284]
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15
[SID103241616]
IC50 5Inhibition of TNAP by analogous luminescence assay [AID459065, Type: Literature]
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16
[SID103241616]
IC50 5Inhibition of IAP by analogous luminescence assay [AID459066, Type: Literature]
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17
[SID103241616]
IC50 5Inhibition of PLAP by analogous luminescence assay [AID459064, Type: Literature]
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18
[SID11111851]
Potency 39.8107qHTS Assay for Agonists of the Thyroid Stimulating Hormone Receptor [AID926, Type: confirmatory]thyroid stimulating hormone receptor [Homo sapiens] [gi:38016895]
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19
[SID103241616]
Km 167Activity of human recombinant TDO expressed in Escherichia coli BL21 using L-tryptophan as substrate by measuring conversion of N-formylkynurenine into kynurenine per mg of protein after 30 mins by Michaelis-Menten steady state analysis [AID612037, Type: Literature]Tryptophan 2,3-dioxygenase [gi:1351188]
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20
[SID103241616]
Km 260Compound was evaluated for Michaelis-Menten constant (Km) in a reaction with tryptophan indole-lyase (tryptophanase) from Escherichia coli [AID228447, Type: confirmatory]
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