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Rutin (CID 5280805) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(31)
 
 
Inactive(243)
 
 
Inconclusive(26)
 
 
Unspecified(18)
 
 
Top Targets:
NR LBD AR(8)
 
 
NR LBD ER(8)
 
 
 
NR LBD PPAR(8)
 
 
NR LBD TR(8)
 
 
Bromo ALL-1(7)
 
 
BioAssay Types:
Confirmatory(277)
 
 
 
 
Literature(41)
 
 
 
 
BioActivity Types:
Potency(223)
 
 
 
 
IC50(68)
 
 
 
 
 
EC50(12)
 
 
 
 
Ki(4)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 229    Data Row: 318   Total Pages: 16   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103516775]
Ki 0.009Binding affinity to adrenergic alpha2c receptor [AID478695, Type: Literature]
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2
[SID103516775]
Ki 0.009Binding affinity to adrenergic alpha2A receptor [AID478696, Type: Literature]
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3
[SID103516775]
IC50 1.17Antioxidant activity assessed as nitric oxide scavenging activity by fluorescent triazofluorescein formation assay [AID453282, Type: Literature]
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4
[SID103516775]
I50 1.886Inhibition of beef heart mitochondrial NADH oxidase assessed per mg of protein [AID338027, Type: Literature]
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5
[SID103516775]
IC50 2.53Antioxidant activity assessed as nitric oxide scavenging activity by spectrophotometry [AID515378, Type: Literature]
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6
[SID26719694]
Potency 3.1623qHTS Assay for Inhibitors and Activators of Human alpha-Glucosidase Cleavage of Glycogen [AID2100, Type: confirmatory]lysosomal alpha-glucosidase preproprotein [Homo sapiens] [gi:119393891]
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7
[SID103516775]
IC50 3.66Nitric oxide scavenging activity assessed as inhibition of DAF2 oxidation [AID289333, Type: Literature]
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8
[SID103516775]
IC50 4.7Antioxidant activity assessed as nitric oxide scavenging activity after 150 mins by Greiss method [AID750845, Type: Literature]
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9
[SID103516775]
IC50 4.7Antioxidant activity assessed as DPPH free radical scavenging activity by spectrophotometric analysis [AID750848, Type: Literature]
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10
[SID103516775]
ID50 7.27Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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11
[SID103516775]
ID50 7.33Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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12
[SID26719694]
Potency 8.9125qHTS Assay for Inhibitors of DNA Polymerase Beta [AID485314, Type: confirmatory]DNA polymerase beta [Homo sapiens] [gi:4505931]
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13
[SID103516775]
IC50 10.6Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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14
[SID103516775]
IC50 12.3Antioxidant activity assessed as DPPH radical scavenging activity [AID333567, Type: Literature]
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15
[SID103516775]
IC50 12.34Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356577, Type: Literature]
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16
[SID103516775]
IC50 13Inhibition of aldose reductase in rat lens homogenates by fluorophotometer [AID335838, Type: Literature]Aldose reductase [gi:1168407]
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17
[SID26719694]
Potency 14.1254qHTS Assay for Inhibitors of Human Jumonji Domain Containing 2E (JMJD2E) [AID2147, Type: confirmatory]Chain A, Crystal Structure Of The Human 2-Oxoglutarate Oxygenase Loc390245 [gi:221046486]
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18
[SID103516775]
IC50 18.5Metal chelating activity of the compound after 10 mins by spectrophotometric analysis [AID750849, Type: Literature]
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19
[SID103516775]
IC50 19.4Antioxidant activity assessed as hydroxyl radical scavenging activity after 15 mins by spectrophotometric analysis [AID750846, Type: Literature]
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20
[SID29216321]
Potency 23.7781qHTS for Inhibitors of Polymerase Kappa [AID588579, Type: confirmatory]DNA polymerase kappa [Homo sapiens] [gi:7705344]
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