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Arachidonic Acid (CID 444899) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(48)
 
 
Inactive(175)
 
 
Inconclusive(37)
 
 
Unspecified(16)
 
 
Top Targets:
PLDc mTdp1 2(10)
 
 
 
 
NR LBD TR(8)
 
 
Tubulin-bindi..(8)
 
 
 
 
HELICc(7)
 
 
 
 
PLN02808(7)
 
 
BioAssay Types:
Confirmatory(243)
 
 
 
 
Literature(33)
 
 
 
BioActivity Types:
Potency(220)
 
 
 
 
IC50(33)
 
 
 
 
EC50(2)
 
 
 
Kd(2)
 
 
 
Ki(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 138    Data Row: 276   Total Pages: 14   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103178961]
IC50 0.0047Concentration required to inhibit production of LTC4 from THP-1 cells stimulated with A-23187 [AID209196, Type: Literature]
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2
[SID26747902]
Potency 0.0794qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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3
[SID103178961]
Kd 0.18Binding affinity against Adipocyte lipid binding protein [AID32788, Type: Literature]
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4
[SID103178961]
IC50 0.18Concentration required to inhibit production of PGE-2 from THP-1 cells stimulated with A-23187 [AID209197, Type: Literature]
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5
[SID103178961]
IC50 0.3Inhibition of mPGES1 [AID405533, Type: Literature]
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6
[SID26753719]
Potency 0.3162qHTS Assay for Inhibitors of 15-hLO (15-human lipoxygenase) [AID887, Type: confirmatory]15-lipoxygenase, partial [Homo sapiens] [gi:1832253]
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7
[SID103178961]
Ki 0.33Ki values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977601, Type: Literature]
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8
[SID103178961]
IC50 0.60256pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B1-transfected CHO cells [AID977600, Type: Literature]
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9
[SID103178961]
Ki 0.82Ki values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977604, Type: Literature]
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10
[SID103178961]
IC50 0.94Concentration required to inhibit production of LTB4 from whole blood stimulated with A-23187 [AID223075, Type: Literature]
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11
[SID103178961]
Km 1Activity of COX2 [AID336480, Type: Literature]
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12
[SID103178961]
IC50 1.07152pIC50 values for sodium fluorescein (10 uM) uptake in OATP1B3-transfected CHO cells [AID977603, Type: Literature]
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13
[SID103178961]
IC50 1.2Inhibition of PPAR-alpha (unknown origin) by SPA assay [AID1094404, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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14
[SID103178961]
IC50 1.2Displacement of [3H]GW2331 from Homo sapiens (human) PPARalpha receptor by scintillation proximity assay [AID1114584, Type: confirmatory]Peroxisome proliferator-activated receptor alpha [gi:3041727]
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15
[SID103178961]
IC50 1.6Displacement of [3H]BRL49653 from Homo sapiens (human) PPARgamma receptor by scintillation proximity assay [AID1114583, Type: confirmatory]Peroxisome proliferator-activated receptor gamma [gi:13432234]
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16
[SID26753719]
Potency 1.9953qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain A, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921310]
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17
[SID26753719]
Potency 1.9953qHTS Assay for Inhibitors of HSD17B4, hydroxysteroid (17-beta) dehydrogenase 4 [AID893, Type: confirmatory]Chain B, The Structure Of Wild-Type Human Hadh2 (17beta-Hydroxysteroid Dehydrogenase Type 10) Bound To Nad+ At 1.2 A [gi:122921311]
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18
[SID26747902]
Potency 2.2387qHTS Assay for Inhibitors of RecQ-Like Dna Helicase 1 (RECQ1) [AID2549, Type: confirmatory]Chain A, Structure Of Human Recq-Like Helicase In Complex With A Dna Substrate [gi:282403581]
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19
[SID26747902]
Potency 2.8184qHTS Assay for Inhibitors of Aldehyde Dehydrogenase 1 (ALDH1A1) [AID1030, Type: confirmatory]aldehyde dehydrogenase 1 family, member A1 [Homo sapiens] [gi:30582681]
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20
[SID103178961]
IC50 3.1Displacement of [3H]GW2433 from Homo sapiens (human) PPARdelta receptor by scintillation proximity assay [AID1114582, Type: confirmatory]Peroxisome proliferator-activated receptor delta [gi:417522]
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