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Iodoquinol (CID 3728) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(43)
 
 
Inactive(285)
 
 
Inconclusive(62)
 
 
Unspecified(108)
 
 
Top Targets:
7tm 4(33)
 
 
 
 
p450(10)
 
 
 
NR LBD ER(6)
 
 
 
 
 
PLDc mTdp1 2(6)
 
 
 
 
NR LBD TR(6)
 
 
 
BioAssay Types:
Confirmatory(498)
 
 
 
 
 
BioActivity Types:
Potency(291)
 
 
 
 
 
IC50(157)
 
 
 
 
 
EC50(19)
 
 
 
AC50(10)
 
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 430    Data Row: 498   Total Pages: 25   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID855609]
Potency 0.1995qHTS Assay for Identification of Small Molecule Antagonists for Hypoxia Response Element Signaling Pathway [AID915, Type: confirmatory]hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) [Homo sapiens] [gi:32879895]
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2
[SID103293005]
IC50 0.294DRUGMATRIX: Protein Serine/Threonine Kinase, ERK2 enzyme inhibition (substrate: Myelin Basic Protein) [AID625181, Type: confirmatory]Mitogen-activated protein kinase 1 [gi:119554]
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3
[SID855609]
AC50_uM 0.314Anti-Malarial Hsp90 Inhibitors Measured in Microorganism System Using Plate Reader - 2121-01_Inhibitor_Dose_CherryPick_Activity [AID540268, Type: confirmatory]HSP90 [Plasmodium falciparum 3D7] [gi:124809506]
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4
[SID26746925]
Potency 0.3548qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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5
[SID103293005]
IC50 0.364DRUGMATRIX: Protein Serine/Threonine Kinase, p38alpha enzyme inhibition (substrate: Myelin Basic Protein) [AID625182, Type: confirmatory]Mitogen-activated protein kinase 14 [gi:2499600]
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6
[SID855609]
AC50_uM 0.391HsHsp90 Counterscreen Measured in Microorganism System Using Plate Reader - 2121-02_Inhibitor_Dose_CherryPick_Activity [AID540270, Type: confirmatory]heat shock protein HSP 90-alpha isoform 2 [Homo sapiens] [gi:154146191]
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7
[SID855609]
EC50_MICROM 0.7Dose Response of TOR pathway GFP-fusion proteins in Saccharomyes cerevisiae specifically LAP4 based on MLPCN hits [AID2745, Type: confirmatory]LAP4 [Saccharomyces cerevisiae] [gi:486173]
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8
[SID26746925]
Potency 0.7079VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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9
[SID103293005]
IC50 0.906DRUGMATRIX: Peptidase, Angiotensin Converting Enzyme enzyme inhibition (substrate: FAPGG) [AID625173, Type: confirmatory]Angiotensin-converting enzyme [gi:2822103]
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10
[SID103293005]
IC50 0.933DRUGMATRIX: Adenosine A3 radioligand binding (ligand: AB-MECA) [AID625196, Type: confirmatory]Adenosine receptor A3 [gi:1351831]
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11
[SID103293005]
IC50 1.571DRUGMATRIX: Protein Tyrosine Kinase, Fyn enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625185, Type: confirmatory]Tyrosine-protein kinase Fyn [gi:125370]
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12
[SID103293005]
IC50 1.889DRUGMATRIX: Protein Tyrosine Kinase, EGF Receptor enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625184, Type: confirmatory]Epidermal growth factor receptor [gi:2811086]
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13
[SID103293005]
IC50 2.461DRUGMATRIX: Protein Tyrosine Kinase, LCK enzyme inhibition (substrate: Poly(Glu:Tyr)) [AID625187, Type: confirmatory]Tyrosine-protein kinase Lck [gi:125474]
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14
[SID855609]
Potency 2.5119qHTS for inhibitors of ROR gamma transcriptional activity [AID2551, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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15
[SID855609]
Potency 3.6626qHTS for induction of synthetic lethality in tumor cells producing 2HG: qHTS for the HT-1080-NT fibrosarcoma cell line [AID686970, Type: confirmatory]IDH1 [Homo sapiens] [gi:49168486]
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16
[SID855609]
Potency 4.4668VP16 counterscreen qHTS for inhibitors of ROR gamma transcriptional activity [AID2546, Type: confirmatory]nuclear receptor ROR-gamma isoform 1 [Mus musculus] [gi:188536040]
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17
[SID855609]
AC50_uM 4.87HTS for PAX8 inhibitors using PAX8 luciferase reporter gene assay in RMG-I cells Measured in Cell-Based System Using Plate Reader - 7054-01_Inhibitor_Dose_CherryPick_Activity [AID687027, Type: confirmatory]PAX8 [Homo sapiens] [gi:998701]
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18
[SID103293005]
IC50 5.264DRUGMATRIX: Protein Serine/Threonine Kinase, ERK1 enzyme inhibition (substrate: Myelin Basic Protein) [AID625180, Type: confirmatory]Mitogen-activated protein kinase 3 [gi:232066]
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19
[SID144204374]
Potency-Replicate_1 6.007qHTS assay to identify small molecule antagonists of the estrogen receptor alpha (ER-alpha) signaling pathway [AID743069, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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20
[SID855609]
EC50 7.36Fluorescent HTS Cytotoxicity/Cell viability assay (HPDE-C7K cells) [AID431, Type: confirmatory]
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