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Diflubenzuron (CID 37123) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(8)
 
 
Inactive(197)
 
 
Inconclusive(21)
 
 
Top Targets:
NR LBD PPAR(13)
 
 
 
NR LBD AR(10)
 
 
 
NR LBD ER(10)
 
 
 
 
NR LBD TR(10)
 
 
NR LBD VDR(7)
 
 
 
BioAssay Types:
Confirmatory(226)
 
 
 
 
BioActivity Types:
Potency(221)
 
 
 
 
IC50(2)
 
 
EC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 157    Data Row: 226   Total Pages: 12   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103230247]
IC50 0.01905Inhibition of chitin synthesis in 20-hydroxyecdysone-stimulated Chilo suppressalis (rice stem borer) larval integument assessed as inhibition of N-acetyl-{1-14C]-glucosamine after 72 hr by liquid scintillation counting in presence of piperonyl butoxide [AID1108928, Type: confirmatory]
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2
[SID103230247]
EC50 0.02Insecticidal activity against Chilo suppressalis (rice stem borer) larvae assessed as inhibition of incorporation of N-acetyl-[1-14C]glucosamine [AID1099671, Type: confirmatory]
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3
[SID103230247]
IC50 0.02042Inhibition of chitin synthesis in 20-hydroxyecdysone-stimulated Chilo suppressalis (rice stem borer) larval integument assessed as inhibition of N-acetyl-{1-14C]-glucosamine after 72 hr by liquid scintillation counting [AID1108932, Type: confirmatory]
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4
[SID144209167]
Potency-Replicate_1 0.0971qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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5
[SID144213455]
Potency-Replicate_1 0.6113qHTS assay to identify small molecule that activate the aryl hydrocarbon receptor (AhR) signaling pathway [AID743085, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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6
[SID144213455]
Potency-Replicate_1 2.4337qHTS assay to identify small molecule agonists of the estrogen receptor alpha (ER-alpha) signaling pathway using the BG1 cell line [AID743079, Type: confirmatory]estrogen nuclear receptor alpha [Homo sapiens] [gi:348019627]
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7
[SID26753710]
Potency 2.5119qHTS assay for environmental chemicals that activate the Aryl hydrocarbon Receptor (AhR) signaling pathway [AID651777, Type: confirmatory]aryl hydrocarbon receptor [Homo sapiens] [gi:51095037]
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8
[SID26753710]
Potency 15.8489qHTS assay for small molecule agonists of retinoid X receptor alpha signaling [AID588544, Type: confirmatory]retinoid X nuclear receptor alpha [Homo sapiens] [gi:325495497]
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9
[SID144209167]
Potency-Replicate_1 0.4866qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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10
[SID144213455]
Potency-Replicate_1 0.5448qHTS assay to identify aromatase inhibitors [AID743083, Type: confirmatory]cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a [Homo sapiens] [gi:119597822]
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11
[SID144209167]
Potency-Replicate_1 1.9371qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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12
[SID26747819]
Potency 3.1623qHTS for Inhibitors of binding or entry into cells for Marburg Virus [AID720532, Type: confirmatory]gene 4 small orf - Marburg virus [Marburg marburgvirus] [gi:420597]
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13
[SID26747819]
Potency 19.9526qHTS for Inhibitors of binding or entry into cells for Lassa Virus [AID720533, Type: confirmatory]
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14
[SID144213455]
Potency-Replicate_1 34.3762qHTS assay to identify small molecule antagonists of the androgen receptor (AR) signaling pathway using the MDA cell line [AID743042, Type: confirmatory]AR protein [Homo sapiens] [gi:124375976]
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15
[SID26747819]
Potency qHTS Assay for Inhibitors of GCN5L2 [AID504327, Type: confirmatory]histone acetyltransferase KAT2A [Homo sapiens] [gi:153791535]
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16
[SID26747819]
Potency qHTS Assay for Inhibitors of 12-hLO (12-human lipoxygenase) [AID1452, Type: confirmatory]arachidonate 12-lipoxygenase, 12S-type [Homo sapiens] [gi:154426292]
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17
[SID26747819]
Potency qHTS for Inducers of the Endoplasmic Reticulum Stress Response (ERSR) in Human Glioma: qHTS [AID602332, Type: confirmatory]heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) [Homo sapiens] [gi:168984549]
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18
[SID26747819]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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19
[SID26747819]
Potency Total Fluorescence Counterscreen for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1479, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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20
[SID26753710]
Potency qHTS for Inhibitors of the Interaction of Thyroid Hormone Receptor and Steroid Receptor Coregulator 2 [AID1469, Type: confirmatory]thyroid hormone receptor beta [Homo sapiens] [gi:189491771]
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