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Ibuprofen (CID 3672) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(80)
 
 
Inactive(737)
 
 
Inconclusive(69)
 
 
Unspecified(148)
 
 
Top Targets:
prostaglandin..(58)
 
 
 
7tm 4(40)
 
 
 
NR LBD TR(18)
 
 
 
NR LBD ER(17)
 
 
 
 
 
NR LBD PPAR(17)
 
 
 
BioAssay Types:
Confirmatory(904)
 
 
 
 
 
Literature(130)
 
 
 
 
 
BioActivity Types:
Potency(650)
 
 
 
 
 
IC50(279)
 
 
 
 
 
EC50(11)
 
 
Ki(10)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 718    Data Row: 1034   Total Pages: 52   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103174500]
IC50 0.1Inhibition activity against recombinant human Prostaglandin G/H synthase 2 [AID162632, Type: Literature]
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2
[SID103174500]
IC50 0.212DRUGMATRIX: Cyclooxygenase COX-1 enzyme inhibition (substrate: Arachidonic acid) [AID625243, Type: confirmatory]Prostaglandin G/H synthase 1 [gi:317373262]
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3
[SID103174500]
IC50 0.22Inhibition of PGE-2 production in 3T3 (murine fibroblast) cell culture. [AID160863, Type: Literature]
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4
[SID103174500]
IC50 0.29Inhibition of COX-1 in human washed platelet assessed as inhibition of 0.5 uM arachidonic acid-induced TXB2 formation incubated for 25 mins prior to arachidonic acid challenge measured after 30 mins by radioimmunoassay [AID747932, Type: Literature]Prostaglandin G/H synthase 1 [gi:317373262]
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5
[SID103174500]
IC50 1.06Reversible competitive inhibition of prostaglandin G/H synthase 1 [AID162150, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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6
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID288822, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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7
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID344874, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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8
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immunoassay [AID352496, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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9
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID368229, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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10
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID461113, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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11
[SID103174500]
IC50 1.1Inhibition of ovine COX2 by enzyme immuno assay [AID622556, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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12
[SID103174500]
IC50 1.1Inhibition of human recombinant COX-2 by enzyme immuno assay [AID443725, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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13
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID447529, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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14
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immunoassay [AID457929, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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15
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 by enzyme immuno assay [AID474248, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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16
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID724444, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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17
[SID103174500]
IC50 1.1Inhibition of human recombinant COX2 [AID648862, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
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18
[SID103174500]
IC50 1.1Inhibition of bovine COX2 by enzyme immunoassay [AID393820, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914301]
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19
[SID103174500]
IC50 1.1In vitro inhibitory concentration against COX-2 enzyme [AID240796, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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20
[SID103174500]
IC50 1.1Inhibition of human COX2 by enzyme immunoassay [AID494635, Type: Literature]Prostaglandin G/H synthase 2 [gi:3915797]
View