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BioActivity Data for Compound SMR000628973 (CID 20910602)

Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(7)
 
 
Inactive(134)
 
 
Inconclusive(10)
 
 
Unspecified(1)
 
 
Top Targets:
RasGEF(4)
 
 
7tm 4(3)
 
 
PLDc mTdp1 2(3)
 
 
 
PHA02644(3)
 
 
 
Pyr redox dim(3)
 
 
BioAssay Types:
Confirmatory(152)
 
 
 
 
 
BioAssay Categories:
Biochemical(2)
 
 
Cell-based(7)
 
 
 
Toxicity(4)
 
 
BioActivity Types:
Potency(115)
 
 
 
 
 
IC50(27)
 
 
AC50(4)
 
 
 
EC50(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 143    Data Row: 152   Total Pages: 8   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID49735911]
AC50_uM 1.01Inhibitors of Epstein-Barr LMP1 inducible NF-kappaB luciferase reporter Measured in Cell-Based System Using Plate Reader - 2122-01_Inhibitor_Dose_CherryPick_Activity [AID588343, Type: confirmatory]
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2
[SID49735911]
Potency 5.1735qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in absence of CPT [AID686978, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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3
[SID49735911]
Potency 5.1735Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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4
[SID49735911]
Potency 10qHTS Assay for Inhibitors of Hepatitis C Virus (HCV) [AID651820, Type: confirmatory]
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5
[SID49735911]
Potency 16.3601qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in presence of CPT [AID686979, Type: confirmatory]TDP1 protein [Homo sapiens] [gi:79154014]
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6
[SID49735911]
AC50_uM 71.509Viability counterscreen of potential LMP-1 inhibitors in HEK293 cell background Measured in Cell-Based System Using Plate Reader - 2122-02_Inhibitor_Dose_CherryPick_Activity [AID504861, Type: confirmatory]LMP1 [Human herpesvirus 4] [gi:23893668]
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7
[SID49735911]
AC50_uM 107.75TES1 - eGFP vs TES2 -dsRED Pathway Differentiation Measured in Cell-Based System Using Imaging - 2122-04_Inhibitor_Dose_CherryPick_Activity [AID588398, Type: confirmatory]LMP1 [Human herpesvirus 4] [gi:23893668]
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8
[SID49735911]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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9
[SID49735911]
Potency 7.0795qHTS for Activators of Integrin-Mediated Alleviation for Muscular Dystrophy [AID624291, Type: confirmatory]Glycoprotein hormones alpha chain [gi:121312]
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10
[SID49735911]
Potency 14.1254qHTS Inhibitors of AmpC Beta-Lactamase (assay without detergent) [AID485341, Type: confirmatory]Chain A, Ampc Beta-Lactamase In Complex With 4-Methanesulfonylamino Benzoic Acid [gi:119389684]
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11
[SID49735911]
Potency qHTS Assay for Identifying a Potential Treatment of Ataxia-Telangiectasia [AID485349, Type: confirmatory]serine-protein kinase ATM [Homo sapiens] [gi:71902540]
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12
[SID49735911]
qHTS of Yeast-based Assay for SARS-CoV PLP [AID485353, Type: confirmatory]orf1ab polyprotein (pp1ab) [SARS coronavirus] [gi:30124074]
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13
[SID49735911]
Potency qHTS Assay for the Inhibitors of Schistosoma Mansoni Peroxiredoxins [AID485364, Type: confirmatory]thioredoxin glutathione reductase [Schistosoma mansoni] [gi:15149312]
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14
[SID49735911]
Potency qHTS Assay to Find Inhibitors of T. brucei phosphofructokinase [AID485367, Type: confirmatory]ATP-dependent phosphofructokinase [Trypanosoma brucei brucei strain 927/4 GUTat10.1] [gi:72386991]
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15
[SID49735911]
Potency qHTS Assay for Inhibitors of the Phosphatase Activity of Eya2 [AID488837, Type: confirmatory]eyes absent homolog 2 isoform a [Homo sapiens] [gi:26667227]
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16
[SID49735911]
IC50 Elucidation of physiology of non-replicating, drug-tolerant Mycobacterium tuberculosis [AID488890, Type: confirmatory]
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17
[SID49735911]
IC50 Primary and Confirmatory Screening for Inhibitors of Bacterial Capsule Biogenesis [AID488966, Type: confirmatory]
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18
[SID49735911]
Potency qHTS assay of beta-arrestin-biased ligands of beta2-adrenergic receptor [AID492947, Type: confirmatory]beta-2 adrenergic receptor [Homo sapiens] [gi:4501969]
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19
[SID49735911]
Potency qHTS Assay for Iinhibitors of HIV-1 Budding by Blocking the Interaction of PTAP/TSG101 [AID493005, Type: confirmatory]tumor susceptibility gene 101 protein [Homo sapiens] [gi:5454140]
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20
[SID49735911]
Potency qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504466, Type: confirmatory]ATAD5 protein, partial [Homo sapiens] [gi:116283940]
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