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BioActivity Data for Compound Ethylene Glycol (CID 174)

Filters: All Data » confirmatory      
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BioActivity Outcomes:
Inactive(377)
 
 
Inconclusive(14)
 
 
Unspecified(123)
 
 
Top Targets:
7tm 4(30)
 
 
 
NR LBD PPAR(13)
 
 
 
NR LBD ER(12)
 
 
 
 
p450(11)
 
 
 
NR LBD AR(11)
 
 
 
 
BioAssay Types:
Confirmatory(506)
 
 
 
 
Literature(8)
 
 
 
BioAssay Categories:
Biochemical(117)
 
 
 
Cell-based(79)
 
 
 
Toxicity(39)
 
 
 
 
ADME(3)
 
 
In vitro(116)
 
 
BioActivity Types:
Potency(345)
 
 
 
 
IC50(123)
 
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 430    Data Row: 514   Total Pages: 26   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103601826]
CC50 221Cytotoxicity against human HL60 cells in presence of RPMI1640 containing 10% fetal bovine serum by trypan blue exclusion test [AID382489, Type: Literature]
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2
[SID103601826]
CC50 385Cytotoxicity against human HSC4 cells by MTT method [AID382488, Type: Literature]
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3
[SID103601826]
CC50 400Cytotoxicity against human gingival fibroblast by MTT method [AID382490, Type: Literature]
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4
[SID103601826]
CC50 400Cytotoxicity against human periodontal ligament fibroblast by MTT method [AID382492, Type: Literature]
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5
[SID103601826]
CC50 400Cytotoxicity against human pulp cells by MTT method [AID382491, Type: Literature]
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6
[SID103601826]
CC50 400Cytotoxicity against human HSC2 by MTT method [AID382487, Type: Literature]
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7
[SID103601826]
IC50 DRUGMATRIX: Leukotriene LTC4 Synthase enzyme inhibition (substrate: LTA4) [AID625144, Type: confirmatory]Leukotriene C4 synthase [gi:239977155]
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8
[SID103601826]
IC50 DRUGMATRIX: Cysteinyl leukotriene receptor 1 radioligand binding (ligand: [3H]LTD4) [AID625145, Type: confirmatory]Cysteinyl leukotriene receptor 1 [gi:20138087]
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9
[SID85272555]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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10
[SID103601826]
IC50 DRUGMATRIX: Nicotinic Acetylcholine radioligand binding (ligand: [125I] Epibatidine) [AID625158, Type: confirmatory]
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11
[SID103601826]
IC50 DRUGMATRIX: Nitric Oxide Synthase, Neuronal (nNOS) radioligand binding (ligand: [3H]L-Arginine) [AID625159, Type: confirmatory]Nitric oxide synthase, brain [gi:266646]
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12
[SID103601826]
IC50 DRUGMATRIX: Opiate delta1 (OP1, DOP) radioligand binding (ligand: [3H] Naltrindole) [AID625161, Type: confirmatory]Delta-type opioid receptor [gi:311033488]
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13
[SID103601826]
IC50 DRUGMATRIX: Platelet Activating Factor (PAF) radioligand binding (ligand: [3H] PAF) [AID625168, Type: confirmatory]Platelet-activating factor receptor [gi:129557]
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14
[SID103601826]
IC50 DRUGMATRIX: Opiate kappa (OP2, KOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625162, Type: confirmatory]Kappa-type opioid receptor [gi:116242691]
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15
[SID103601826]
IC50 DRUGMATRIX: Opiate mu (OP3, MOP) radioligand binding (ligand: [3H] Diprenorphine) [AID625163, Type: confirmatory]Mu-type opioid receptor [gi:2851402]
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16
[SID103601826]
IC50 DRUGMATRIX: Phosphodiesterase PDE3 enzyme inhibition (substrate: [3H]cAMP + cAMP) [AID625165, Type: confirmatory]
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17
[SID103601826]
IC50 DRUGMATRIX: Lipoxygenase 15-LO enzyme inhibition (substrate: Linoleic acid) [AID625146, Type: confirmatory]Arachidonate 15-lipoxygenase [gi:126397]
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18
[SID103601826]
IC50 DRUGMATRIX: Melanocortin MC4 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625148, Type: confirmatory]Melanocortin receptor 4 [gi:60392672]
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19
[SID103601826]
IC50 DRUGMATRIX: Melanocortin MC5 radioligand binding (ligand: [125I] NDP-alpha-MSH) [AID625149, Type: confirmatory]Melanocortin receptor 5 [gi:729996]
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20
[SID103601826]
IC50 DRUGMATRIX: Monoamine Oxidase MAO-A enzyme inhibition (substrate: Kynuramine) [AID625150, Type: confirmatory]Amine oxidase [flavin-containing] A [gi:113978]
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