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Aminolevulinic Acid (CID 137) - Compound BioActivity Data
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Filters: All Data » confirmatory      
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BioActivity Outcomes:
Active(1)
 
 
Inactive(107)
 
 
Inconclusive(2)
 
 
Unspecified(12)
 
 
Top Targets:
RasGEF(4)
 
 
Pyr redox dim(3)
 
 
Geminin(2)
 
 
Snurportin-1..(2)
 
 
MPP ASMase(2)
 
 
 
BioAssay Types:
Confirmatory(112)
 
 
 
 
Literature(10)
 
 
 
BioActivity Types:
Potency(97)
 
 
 
 
IC50(18)
 
 
 
 
Ki(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 116    Data Row: 122   Total Pages: 7   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103182993]
IC50 12.9Antagonist activity at human GABAc Rho1 receptor expressed in Xenopus oocytes assessed as whole cell current production by two electrode voltage clamp method [AID406571, Type: Literature]Gamma-aminobutyric acid receptor subunit rho-1 [gi:223590210]
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2
[SID103182993]
Ki 230TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT2-expressing LLC-PK1 cells [AID681124, Type: Literature]Solute carrier family 15 member 2 [gi:2499990]
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3
[SID103182993]
Km 253The Michaelis-Menten rate of reaction catalyzed by ALA dehydratase from Bacillus subtilis measured spectrophotometrically [AID31307, Type: confirmatory]
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4
[SID103182993]
Ki 790Inhibition constant (Ki) for human intestinal peptide carrier [AID92023, Type: Literature]
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5
[SID103182993]
Ki 960Inhibitory activity against porcine kidney prolidase [AID162623, Type: confirmatory]
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6
[SID103182993]
IC50 1570Cytotoxicity against human HL60 cells after 72 hrs by MTT assay [AID347393, Type: Literature]
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7
[SID103182993]
IC50 1735Cytotoxicity against human MCF7 cells after 72 hrs by Hoechst test [AID347394, Type: Literature]
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8
[SID103182993]
Ki 2200TP_TRANSPORTER: inhibition of Gly-Sar uptake in PEPT1-expressing LLC-PK1 cells [AID681125, Type: Literature]Solute carrier family 15 member 1 [gi:1730492]
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9
[SID103182993]
IC50 2665Cytotoxicity against human U251 cells after 72 hrs by Hoechst test [AID347392, Type: Literature]
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10
[SID103182993]
IC50 2715Antiproliferative activity against human U251 cells assessed as PpIX release pretreated 72 hrs before 360-410 nm light photosensitization measured after 48 hrs by Hoechst test [AID347409, Type: Literature]
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11
[SID103182993]
IC50 2719Antiproliferative activity against human U251 cells assessed as PpIX release after 72 hrs by Hoechst test [AID347408, Type: Literature]
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12
[SID103182993]
IC50 3475Cytotoxicity against human MCF7/DX cells after 72 hrs by Hoechst test [AID347395, Type: Literature]
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13
[SID56322917]
Potency qHTS for Inhibitors of Human Acid Sphingomyelinase Assay: Native Substrate [AID624178, Type: confirmatory]acid sphingomyelinase [Homo sapiens] [gi:179095]
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14
[SID56322917]
Potency 0.1259A quantitative high throughput screen for small molecules that induce DNA re-replication in SW480 colon adenocarcinoma cells. [AID624297, Type: confirmatory]geminin [Homo sapiens] [gi:7705682]
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15
[SID56322917]
Potency 0.7079qHTS Assay for Inhibitors of BAZ2B [AID504333, Type: confirmatory]bromodomain adjacent to zinc finger domain 2B [Homo sapiens] [gi:6683500]
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16
[SID56322917]
Potency qHTS Assay for Inhibitors of JMJD2A-Tudor Domain [AID504339, Type: confirmatory]Chain A, Jmjd2a Tandem Tudor Domains In Complex With A Trimethylated Histone H4-K20 Peptide [gi:162330054]
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17
[SID56322917]
Potency Nrf2 qHTS screen for inhibitors [AID504444, Type: confirmatory]nuclear factor erythroid 2-related factor 2 isoform 2 [Homo sapiens] [gi:224028257]
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18
[SID56322917]
Potency qHTS screen for small molecules that induce genotoxicity in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504466, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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19
[SID56322917]
Potency qHTS screen for small molecules that inhibit ELG1-dependent DNA repair in human embryonic kidney (HEK293T) cells expressing luciferase-tagged ELG1 [AID504467, Type: confirmatory]ATAD5 protein [Homo sapiens] [gi:116283940]
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20
[SID56322917]
Potency Nrf2 qHTS screen for inhibitors: counterscreen for cytotoxicity [AID504648, Type: confirmatory]
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