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Catechin (CID 9064) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(24)
 
 
Inactive(31)
 
 
Inconclusive(2)
 
 
Unspecified(80)
 
 
Top Targets:
prostaglandin..(11)
 
 
 
 
7TM GPCR Srx(3)
 
 
 
Aldo ket red(2)
 
 
RNA dep RNAP(2)
 
 
crotonase-lik..(2)
 
 
BioAssay Types:
Literature(137)
 
 
 
 
 
BioActivity Types:
IC50(33)
 
 
 
 
 
Potency(2)
 
 
EC50(1)
 
 
Kd(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 135    Data Row: 137   Total Pages: 3   Display: Page     
Sort: [Click the result table header to sort]
#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123094711]
IC50 1.61Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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2
[SID123094711]
IC50 2.31Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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3
[SID123094711]
ID50 2.75Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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4
[SID123094711]
ID50 2.86Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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5
[SID123094711]
IC50 2.9Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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6
[SID123094711]
IC50 4.1Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay [AID333439, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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7
[SID123094711]
IC50 4.3Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry [AID650645, Type: Literature]
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8
[SID123094711]
IC50 5.3Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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9
[SID123094711]
IC50 13.1Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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10
[SID123094711]
IC50 20.2Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay [AID333440, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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11
[SID123094711]
IC50 20.2Free radical scavenging activity of DPPH was determined; value taken from reference 11 [AID226690, Type: Literature]
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12
[SID123094711]
IC50 21.1Inhibition of Saccharomyces cerevisiae alcohol dehydrogenase measured every 5 mins for 2 hrs by spectrophotometry [AID650644, Type: Literature]
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13
[SID123094711]
IC50 36.7Inhibition of COX1 [AID332217, Type: Literature]
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14
[SID123094711]
Kd 40.7Binding affinity to COX1 in sheep seminal vesicle [AID333444, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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15
[SID123094711]
IC50 49Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356646, Type: Literature]
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16
[SID123094711]
Induction of supercoiled pSP64 plasmid DNA cleavage assessed as increase in linear duplex form 3 at 10 uM by agarose gel electrophoresis [AID377528, Type: Literature]
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17
[SID123094711]
Antagonist activity at human delta opioid receptor expressed in CHO cells by [35S]GTPgammaS assay [AID311282, Type: Literature]Delta-type opioid receptor [gi:311033488]
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18
[SID123094711]
Antioxidant activity assessed as DPPH radical scavenging activity [AID311580, Type: Literature]
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19
[SID123094711]
Antagonist activity at human kappa opioid receptor expressed in CHO cells by [35S]GTP-gamma-S assay [AID311280, Type: Literature]Kappa-type opioid receptor [gi:116242691]
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20
[SID123094711]
Antioxidant activity assessed as peroxyl radical scavenging activity at 1 to 2 uM by ORAC assay [AID551461, Type: Literature]
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21
[SID123094711]
Antioxidant activity assessed as copper ion radical scavenging activity at 2 uM [AID551462, Type: Literature]
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22
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 1 mg/ml after 18 hrs using crystal violet staining [AID626983, Type: Literature]
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23
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 2 mg/ml after 18 hrs using crystal violet staining [AID626984, Type: Literature]
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24
[SID123094711]
Inhibition of Pseudomonas aeruginosa PAO1 quorum sensing assessed as reduction of biofilm formation at 3 mg/ml after 18 hrs using crystal violet staining [AID626985, Type: Literature]
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25
[SID123094711]
IC50 30Inhibition of aldose reductase in rat lens homogenate [AID356411, Type: Literature]Aldose reductase [gi:1168407]
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26
[SID123094711]
IC50 80Inhibition of COX1 [AID403341, Type: Literature]
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27
[SID123094711]
IC50 80Inhibition of bovine seminal vesicle microsomal COX1-mediated prostaglandin production [AID399411, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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28
[SID123094711]
IC50 93.3Inhibition of COX2 [AID332218, Type: Literature]
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29
[SID123094711]
IC50 100Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometry [AID399340, Type: Literature]
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30
[SID123094711]
IC50 130Inhibition of COX2 [AID403340, Type: Literature]
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31
[SID123094711]
IC50 144Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum NF54 [AID265761, Type: Literature]
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32
[SID123094711]
IC50 183Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production [AID399401, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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33
[SID123094711]
IC50 279Inhibition of bovine seminal microsomal COX1 assessed as PGE2 production preincubated for 10 mins [AID399404, Type: Literature]Prostaglandin G/H synthase 1 [gi:166897622]
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34
[SID123094711]
EC50 345Antiviral activity against HIV1 3B infected in human H9 cells assessed as inhibition of viral replication after 3 days by p24 antigen capture assay [AID332929, Type: Literature]
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35
[SID123094711]
IC50 345Cytotoxicity against human H9 cells after 3 days [AID332930, Type: Literature]
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36
[SID123094711]
IC50 546Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production [AID399402, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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37
[SID123094711]
IC50 647.2Modulation of classical complement pathway system assessed as hemoglobin release by spectrophotometry [AID380219, Type: Literature]
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38
[SID123094711]
IC50 5910Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 mins [AID399405, Type: Literature]Prostaglandin G/H synthase 2 [gi:3914304]
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39
[SID123094711]
Selectivity ratio of IC50 for sheep placental cotyledons COX2 to IC50 for bovine seminal microsomal COX1 preincubated for 10 mins [AID399406, Type: Literature]
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40
[SID123094711]
Inhibition of reduced carboxymethylated kappa-casein fibril formation at 50 ug/mL measured every 5 mins after 1000 mins by thioflavin T staining-based binding assay [AID456183, Type: Literature]
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41
[SID123094711]
Antioxidant activity assessed as formazan formation induced absorbance changes at 25 ppm at 570 nm at 37 degC for 6 hrs by MTT assay [AID492140, Type: Literature]
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42
[SID123094711]
Antiaggregatory activity in human platelets assessed as inhibition of collagen-induced platelet aggregation by aggregometry [AID538214, Type: Literature]
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43
[SID123094711]
Antiaggregatory activity in human platelets assessed as inhibition of thrombin-induced platelet aggregation by aggregometry [AID538215, Type: Literature]
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44
[SID123094711]
Octanol-water partition coefficient, log POW of the compound [AID403810, Type: Literature]
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45
[SID123094711]
Antibacterial activity against Enterococcus faecalis ATCC 29212 after 24 hrs by NCCLS method [AID468508, Type: Literature]
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46
[SID123094711]
Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by NCCLS method [AID468509, Type: Literature]
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47
[SID123094711]
Antibacterial activity against Micrococcus luteus ATCC 10240 after 24 hrs by NCCLS method [AID468510, Type: Literature]
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48
[SID123094711]
Antibacterial activity against Staphylococcus epidermidis ATCC 0155 after 24 hrs by NCCLS method [AID468511, Type: Literature]
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49
[SID123094711]
Antibacterial activity against Bacillus subtilis ATCC 6633 after 24 hrs by NCCLS method [AID468512, Type: Literature]
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50
[SID123094711]
Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by NCCLS method [AID468513, Type: Literature]
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