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Catechin (CID 9064) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(38)
 
 
Inactive(34)
 
 
Inconclusive(2)
 
 
Unspecified(118)
 
 
Top Targets:
prostaglandin..(11)
 
 
 
 
Tryp SPc(8)
 
 
 
 
7tm 4(3)
 
 
 
Aldo ket red(2)
 
 
CAP ED(2)
 
 
BioAssay Types:
Literature(192)
 
 
 
 
 
BioActivity Types:
IC50(37)
 
 
 
 
 
EC50(15)
 
 
Potency(3)
 
 
Kd(2)
 
 
Ki(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 189    Data Row: 192   Total Pages: 10   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID123094711]
Ki 0.6Noncompetitive inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate by Dixon reciprocal plot analysis [AID1066693, Type: Literature]Arginase [gi:74764753]
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2
[SID123094711]
IC50 1.61Antioxidant activity assessed as superoxide-scavenging activity by nitrite method [AID399341, Type: Literature]
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3
[SID123094711]
IC50 1.7Inhibition of Leishmania amazonensis recombinant arginase expressed in Escherichia coli Rosetta (DE3) pLysS using L-arginine as substrate incubated for 10 mins prior to substrate addition measured after 10 mins by colorimetry [AID1066694, Type: Literature]Arginase [gi:74764753]
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4
[SID123094711]
IC50 2.31Antioxidant activity assessed as superoxide anion radical scavenging activity [AID311581, Type: Literature]
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5
[SID123094711]
ID50 2.75Inhibition of Moloney murine leukemia virus reverse transcriptase using (riboadenylic acid)n(deoxythymidylic acid)12-18 as template primer by liquid scintillation counting [AID339056, Type: Literature]
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6
[SID123094711]
ID50 2.86Inhibition of Moloney murine leukemia virus reverse transcriptase using (ribocytidylic acid)n(deoxyguanylic acid)12-18 as template primer by liquid scintillation counting [AID339057, Type: Literature]
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7
[SID123094711]
IC50 2.9Inhibition of beta amyloid (1 to 40) fibril formation by thioflavin T staining-based binding assay [AID456188, Type: Literature]
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8
[SID123094711]
IC50 4.1Inhibition of peroxidase activity of COX1 in heep seminal vesicle by TMPD assay [AID333439, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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9
[SID123094711]
IC50 4.3Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins by spectrophotometry [AID650645, Type: Literature]
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10
[SID123094711]
IC50 5.3Inhibition of beta amyloid (1 to 42) fibril formation by thioflavin T staining-based binding assay [AID456189, Type: Literature]
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11
[SID123094711]
IC50 13.1Antioxidant activity assessed as superoxide radical anion scavenging activity [AID380203, Type: Literature]
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12
[SID123094711]
IC50 20.2Inhibition of cyclooxygenase activity of COX1 in sheep seminal vesicle in presence of 1 mM phenol by cyclooxygenase assay [AID333440, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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13
[SID123094711]
IC50 20.2Free radical scavenging activity of DPPH was determined; value taken from reference 11 [AID226690, Type: Literature]
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14
[SID123094711]
IC50 21.1Inhibition of Saccharomyces cerevisiae alcohol dehydrogenase measured every 5 mins for 2 hrs by spectrophotometry [AID650644, Type: Literature]
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15
[SID123094711]
IC50 36.7Inhibition of COX1 [AID332217, Type: Literature]
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16
[SID123094711]
Kd 40.7Binding affinity to COX1 in sheep seminal vesicle [AID333444, Type: Literature]Prostaglandin G/H synthase 1 [gi:548481]
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17
[SID123094711]
IC50 49Antioxidant activity assessed as DPPH radical scavenging activity after 30 mins [AID356646, Type: Literature]
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18
[SID123094711]
Kd 49.2Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis [AID768894, Type: Literature]Prothrombin [gi:135807]
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19
[SID123094711]
Competitive inhibition of human thrombin using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measured every 12 secs for 10 mins by Lineweaver-Burk plot analysis [AID768892, Type: Literature]Prothrombin [gi:135807]
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20
[SID123094711]
Relative antioxidant activity assessed as resorcinol equivalents of hydroperoxyl scavenging activity at acidic pH by BR oscillating reaction method [AID772994, Type: Literature]
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