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2-Anilino-1,4-naphthoquinone (CID 81124) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(5)
 
 
Inactive(13)
 
 
Unspecified(11)
 
 
Top Targets:
Anthrax-tox M(3)
 
 
Toxin trans(3)
 
 
RNA dep RNAP(1)
 
 
crotonase-lik..(1)
 
 
BioAssay Types:
Literature(29)
 
 
 
 
BioActivity Types:
IC50(3)
 
 
 
EC50(1)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 23    Data Row: 29   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103284973]
PD50 0.064Neuroprotective activity in mouse HT22 cells assessed as prevention from glutamate-induced oxidative cell death by MTS assay [AID736844, Type: Literature]
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2
[SID103284973]
EC50 0.239Inhibitory activity on acetylcholine-induced vasorelaxation of phenylephrine-precontracted rat aorta with intact endothelium [AID175494, Type: Literature]
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3
[SID103284973]
IC50 5.52Cytotoxicity against human DU145 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763580, Type: Literature]
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4
[SID103284973]
TC50 7Neurotoxicity in mouse HT22 cells assessed as cell viability after 24 hrs by MTS assay [AID736842, Type: Literature]
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5
[SID103284973]
IC50 31.25Cytotoxicity against human HT-29 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763578, Type: Literature]
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6
[SID103284973]
IC50 100Cytotoxicity against human MDA-MB-231 cells assessed as growth inhibition after 72 hrs by MTS assay [AID763579, Type: Literature]
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7
[SID103284973]
Therapeutic index, ratio of cytotoxic TC50 for mouse HT22 cells to neuroprotective PD50 for mouse HT22 cells [AID736843, Type: Literature]
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8
[SID103284973]
Percent of maximal acetylcholine (ACh)-induced vasorelaxation of the rat aorta [AID180024, Type: Literature]
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9
[SID103284973]
Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay [AID548148, Type: Literature]
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10
[SID103284973]
Cytotoxicity against human T24 cells after 48 hrs by MTT assay [AID548149, Type: Literature]
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11
[SID103284973]
Cytotoxicity against human DU145 cells after 48 hrs by MTT assay [AID548150, Type: Literature]
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12
[SID103284973]
Cytotoxicity against mouse BALB/3T3 cells after 48 hrs by MTT assay [AID548151, Type: Literature]
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13
[SID103284973]
Selectivity index, ratio of EC50 for mouse BALB/3T3 cells to EC50 for human DU145 cells [AID548152, Type: Literature]
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14
[SID103284973]
Selectivity index, ratio of EC50 for mouse BALB/3T3 cells to EC50 for human MCF7 cells [AID548153, Type: Literature]
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15
[SID103284973]
Selectivity index, ratio of EC50 for mouse BALB/3T3 cells to EC50 for human T24 cells [AID548154, Type: Literature]
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16
[SID103284973]
Lipophilicity, log P of the compound [AID548155, Type: Literature]
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17
[SID24824101]
Antagonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504810, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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18
[SID24824101]
Inverse Agonists of the Thyroid Stimulating Hormone Receptor: HTS campaign [AID504812, Type: Literature]TSHR protein [Homo sapiens] [gi:118341367]
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19
[SID24824101]
High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set [AID588497, Type: Literature]botulinum neurotoxin type F, BoNT/F [Clostridium botulinum Bf] [gi:168184763]
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20
[SID24824101]
High-throughput multiplex microsphere screening for inhibitors of toxin protease, specifically Botulinum neurotoxin light chain F protease, MLPCN compound set [AID588497, Type: Literature]botulinum neurotoxin type F, BoNT/F [Clostridium botulinum Bf] [gi:168184763]
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