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Phenylthiourea (CID 676454) - Compound BioActivity Data
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Filters: All Data » Literature      
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BioActivity Outcomes:
Active(9)
 
 
Inactive(6)
 
 
Unspecified(8)
 
 
Top Targets:
Tyrosinase(7)
 
 
 
CAP ED(4)
 
 
M20 DapE prot..(1)
 
 
RNA dep RNAP(1)
 
 
crotonase-lik..(1)
 
 
BioAssay Types:
Literature(23)
 
 
 
 
BioActivity Types:
IC50(8)
 
 
 
Potency(4)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 19    Data Row: 23   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103565465]
IC50 1.5Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate by spectrometric analysis [AID626570, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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2
[SID103565465]
IC50 1.8Inhibition of tyrosinase in alpha-MSH-induced mouse B16 cells [AID494974, Type: Literature]
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3
[SID103565465]
IC50 1.8Inhibition of tyrosinase [AID457969, Type: Literature]
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4
[SID103565465]
IC50 1.8Inhibition of mushroom tyrosinase [AID331282, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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5
[SID103565465]
IC50 5.4Inhibition of melanogenesis in mouse B16 cells [AID480030, Type: Literature]
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6
[SID46391587]
IC50 43Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Catechol Oxidase From Ipomoea Batatas (Sweet Potatoes)- Inhibitor Complex With Phenylthiourea (Ptu) [gi:6137621]
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7
[SID46391587]
IC50 43Experimentally measured binding affinity data (IC50) for protein-ligand complexes derived from PDB [AID977608, Type: Literature]Chain A, Catechol Oxidase From Ipomoea Batatas (Sweet Potatoes)- Inhibitor Complex With Phenylthiourea (Ptu) [gi:6137621]
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8
[SID103565465]
Inhibition of tyrosinase in human HEMn-MP assessed as reduction of melanin level at 100 uM after 2 days by spectrophotometric analysis [AID492070, Type: Literature]Tyrosinase [gi:401235]
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9
[SID46391587]
Experimentally measured binding affinity data derived from PDB [AID1811, Type: Literature]Chain A, Catechol Oxidase From Ipomoea Batatas (Sweet Potatoes)- Inhibitor Complex With Phenylthiourea (Ptu) [gi:6137621]
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10
[SID103565465]
IC50 100Inhibition of Haemophilus influenzae recombinant DapE [AID467024, Type: Literature]Succinyl-diaminopimelate desuccinylase [gi:1169224]
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11
[SID103565465]
Inhibition of melanogenesis in mouse B16 cells at 10 uM [AID480029, Type: Literature]
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12
[SID103565465]
Inhibition of alpha-MSH-induced melanin production in mouse B16 cells at 100 uM after 72 hrs [AID457971, Type: Literature]
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13
[SID103565465]
Depigmentation effect in mouse Melan-a cells assessed as difference between cell viability and melanin content at 30 uM [AID497307, Type: Literature]
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14
[SID103565465]
Cytotoxicity against mouse Melan-a cells assessed as cell viability at 30 uM [AID497308, Type: Literature]
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15
[SID103565465]
Inhibition of mushroom tyrosinase activity using L-tyrosine as substrate at 10 uM by spectrometric analysis [AID626569, Type: Literature]Polyphenol oxidase 2 [gi:6686057]
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16
[SID103565465]
Inhibition of melanin production in mouse B16 cells at 100 uM [AID331283, Type: Literature]
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17
[SID103565465]
Antimelanogenic activity in mouse B16 cells assessed as inhibition of alpha-MSH-induced melanogenesis at 100 uM [AID494973, Type: Literature]
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18
[SID17388780]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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19
[SID17388780]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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20
[SID17389761]
Potency qHTS Assay for Small Molecule Inhibitors of the Human hERG Channel Activity [AID588834, Type: Literature]potassium voltage-gated channel subfamily H member 2 isoform d [Homo sapiens] [gi:325651834]
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