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BioActivity Data for Compound nitromethane (CID 6375)

Filters: All Data » Literature      
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BioActivity Outcomes:
Inactive(11)
 
 
Inconclusive(4)
 
 
Unspecified(17)
 
 
Top Targets:
CAP ED(2)
 
 
MetAP1(1)
 
 
MetAP2(1)
 
 
Tryp SPc(1)
 
 
BioAssay Types:
Literature(32)
 
 
 
 
BioActivity Types:
IC50(12)
 
 
 
Potency(2)
 
 
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Chemical Probe    Active    Inactive    Inconclusive    Unspecified   

Total Bioassays: 31    Data Row: 32   Total Pages: 2   Display: Page     
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#SubstanceActivityBioAssayTargetLinks
OutcomeTypeValue [μM]
1
[SID103179179]
IC50 100Cytotoxicity against human SW707 cells after 72 hrs by crystal violet staining method [AID736753, Type: Literature]
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2
[SID103179179]
IC50 100Cytotoxicity against human MeWo cells after 72 hrs by crystal violet staining method [AID736757, Type: Literature]
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3
[SID103179179]
IC50 100Cytotoxicity against human A431 cells after 72 hrs by crystal violet staining method [AID736758, Type: Literature]
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4
[SID103179179]
IC50 100Cytotoxicity against human Flow 2002 cells after 72 hrs by crystal violet staining method [AID736759, Type: Literature]
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5
[SID103179179]
IC50 100Cytotoxicity against human Capan1 cells after 72 hrs by crystal violet staining method [AID736754, Type: Literature]
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6
[SID103179179]
IC50 100Cytotoxicity against human CaSki cells after 72 hrs by crystal violet staining method [AID736755, Type: Literature]
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7
[SID103179179]
IC50 100Cytotoxicity against human Calu6 cells after 72 hrs by crystal violet staining method [AID736756, Type: Literature]
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8
[SID103179179]
IC50 100Cytotoxicity against human HaCaT cells after 72 hrs by crystal violet staining method [AID736760, Type: Literature]
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9
[SID103179179]
Antibacterial activity against methicillin-resistant Staphylococcus aureus NCTC 10442 after 20 to 24 hrs by broth microdilution assay [AID736761, Type: Literature]
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10
[SID103179179]
Antibacterial activity against methicillin-sensitive Staphylococcus aureus ATCC 25923 after 20 to 24 hrs by broth microdilution assay [AID736762, Type: Literature]
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11
[SID103179179]
Antibacterial activity against Escherichia coli ATCC 25922 after 20 to 24 hrs by broth microdilution assay [AID736367, Type: Literature]
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12
[SID103179179]
Aqueous solubility [AID19262, Type: Literature]
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13
[SID103179179]
Partition coefficient (logP) [AID23443, Type: Literature]
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14
[SID103179179]
Toxicity determined using Tadpole Narcosis Test [AID212400, Type: Literature]
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15
[SID103179179]
Octanol-water partition coefficient, log P of the compound [AID343683, Type: Literature]
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16
[SID103179179]
Alkane-water partition coefficient, log P of the compound [AID343684, Type: Literature]
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17
[SID103179179]
Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 20 to 24 hrs by broth microdilution assay [AID736366, Type: Literature]
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18
[SID103179179]
Inhibition of thrombin (unknown origin) expressed in Escherichia coli BL21(lambdaDE3) using Boc-Val-Pro-Arg-AMC as substrate at 25 uM incubated for 15 mins prior to substrate addition measured for 10 mins by fluorometric analysis [AID736764, Type: Literature]Prothrombin [gi:135807]
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19
[SID103179179]
Inhibition of human MetAP2 expressed in Escherichia coli BL21(lambdaDE3) using Met-AMC as substrate at 10 uM incubated for 30 mins prior to substrate addition measured for 15 mins fluorometric analysis [AID736765, Type: Literature]Methionine aminopeptidase 2 [gi:1703273]
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20
[SID103179179]
Inhibition of human MetAP1 expressed in Escherichia coli BL21(lambdaDE3) using Met-AMC as substrate at 10 uM incubated for 30 mins prior to substrate addition measured for 15 mins fluorometric analysis [AID736766, Type: Literature]Methionine aminopeptidase 1 [gi:33302602]
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